Institute of Precision Medicine

zu Forschungsinstitute

Präzision, die Therapien besser macht

Es entspricht dem gesunden Menschenverstand, dass bei der Behandlung von Patientinnen und Patienten individuelle Unterschiede berücksichtigt werden müssen, um die Therapie zu verbessern. Die Anpassung von Therapien an individuelle Bedürfnisse (einschließlich medizinischer Produkte und patientenspezifischer Gewebe) und Reaktionen verbessert nicht nur die Wirksamkeit einer Behandlung, sondern verringert auch unerwünschte Wirkungen. Mit der Sequenzierung der 3. Generation, der Metabolomik und anderen Hochdurchsatztechnologien haben wir nun die Möglichkeit, die Diagnose, die Therapieauswahl und das Behandlungsschema viel präziser an den genauen Gesundheitszustand einer Person anzupassen und eine viel genauere Prognose zu stellen. In diesem Zusammenhang bezeichnet der Begriff Präzisionsmedizin einen neu entstehenden Behandlungsansatz, der individuelle genetische/genomische Merkmale sowie Umwelteinflüsse und Lebensgewohnheiten berücksichtigt, auch mittels Data Mining unter Verwendung aufgezeichneter klinischer Daten. Da eine präzise Diagnose und Prognose auf einer Vielzahl von genomischen und umweltbedingten Parametern beruht, sind ausgefeilte rechnerische und statistische Verfahren ein sehr wichtiger Bestandteil dieses Ansatzes.

Am Institute of Precision Medicine wurde eine Vielzahl von Methoden für die Analyse von Biomarkern etabliert und validiert. Datei herunterladen:Diese Methoden können von Fakultätsmitgliedern und anderen Forschungsgruppen, die mit der HFU verbunden sind, für Lehrzwecke und Forschungsprojekte genutzt werden. 

Forschungsprojekte

CoHMed

Connected Health in Medical Mountains - eine Innovations- und Transferpartnerschaft der Hochschule Furtwangen. Teilprojekt zur Entwicklung von funktionellen Oberflächen und deren Biokompatibilität
Link öffnet sich im gleichen Fenster:Zu CoHMed

Apoptose

Die metabolischen Unterschiede zwischen kompensatorischer Zellproliferation und weiterführender Apoptose
Link öffnet sich im gleichen Fenster:Zu Apoptose

VarioPore

Innovative Technologie für eine schnelle und zuverlässige Diagnose von Infektionskrankheiten
Link öffnet sich im gleichen Fenster:Zu VarioPore

WMP

Analyse von Struktur und Funktion des Mikrobioms in Haushalts-Waschmaschinen und auf Textilien zur Entwicklung nachhaltiger Hygienestrategien im modernen Haushalt.
Link öffnet sich im gleichen Fenster:Zu WMP

immENS

Dieses Projekt untersucht die Interaktion von Mikrobiom, Motilität und Darmnervensystem (ENS) im Gastrointestinaltrakt.
Link öffnet sich im gleichen Fenster:Zu immENS

NASH

Im Projekt werden moderne OMICS-Technologien eingesetzt, um die Wirksamkeit nachhaltiger Strategien für die Wäschehygiene unter praxisnahen Bedingungen zu untersuchen.

Link öffnet sich im gleichen Fenster:Zu NASH

Publikationen

Institute of Precision Medicine

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988

2024

Johanna Dabernig-Heinz, Mara Lohde, Martin Hölzer, Adriana Cabal, Rick Conzemius, Christian Brandt, Matthias Kohl, Sven Halbedel, Patrick Hyden, Martin A. Fischer, Ariane Pietzka, Beatriz Daza, Evgeny A. Idelevich, Anna Stöger, Karsten Becker, Stephan Fuchs, Werner Ruppitsch, Ivo Steinmetz, Christian Kohler, Gabriel E. Wagner A multicenter study on accuracy and reproducibility of nanopore sequencing-based genotyping of bacterial pathogens
Jan Vagedes, Benedikt M. Huber, Mohammad Oli Al Islam, Katrin Vagedes, Matthias Kohl, Tido von Schoen-Angerer Antibiotic Use in a Neonatal Intensive Care Unit Practicing Integrative Medicine — A Retrospective Analysis
Elham Ghazizadeh, Zahra Naseri, Hans-Peter Deigner, Hossein Rahimi, Zeynep Altintas Approaches of wearable and implantable biosensor towards of developing in precision medicine
Weronika Schary, Florian Brockmann, Jonathan Simantzik, Filip Paskali, Matthias Kohl Big Data and Health Analytics explained
Matthias Kohl Comment on: Cytokines (IL1β, IL6, TNFα) and serum cortisol levels may not constitute reliable biomarkers to identify individuals with post-acute sequelae of COVID-19
Lars Saemann, Sven Maier, Matthias Kohl, Andreas Simm, Gabor Szabo Durable versus Temporary Left-Ventricular Assist Devices versus Extracorporeal Membrane Oxygenation for Bridging to Orthotopic Heart Transplantation : A Meta-Analysis
Katrin Vagedes, Silja Kuderer, Rainer Ehmann, Matthias Kohl, Johannes Wildhaber, Rudolf A. Jörres, Jan Vagedes Effect of Buteyko breathing technique on clinical and functional parameters in adult patients with asthma: a randomized, controlled study
Y. H. Le, Matthias Kohl, Simon von Stengel, Michael Uder, Wolfgang Kemmler Effectiveness and Safety of Whole-Body Electromyostimulation on Musculoskeletal Diseases in Middle Aged-Older Adults – A Systematic Review
Sebastian Willert, Simon von Stengel, Matthias Kohl, Michael Uder, Wolfgang Kemmler Effects of Whole-Body Electromyostimulation and Lifestyle Modifications on the Metabolic Syndrome in Premenopausal Overweight Women. A Randomized Controlled Trial
Stephanie Kast, Wolfgang Kemmler, Frank W. Römer, Matthias Kohl, Adam G. Culvenor, Ali Mobasheri, Michael Uder, Simon von Stengel Effects of Whole-body Electromyostimulation on knee pain and physical function in adults with symptomatic knee osteoarthritis: a randomized controlled trial
Kaja Kircher, Oliver Chaudry, Armin M. Nagel, Mansour Ghasemikaram, Michael Uder, Franz Jakob, Matthias Kohl, Wolfgang Kemmler, Klaus Engelke Effects of high-intensity training on fatty infiltration in paraspinal muscles in elderly males with osteosarcopenia – the randomized controlled FrOST study
Wolfgang Kemmler, Matthias Kohl, Simon von Stengel, Sebastian Willert, Stephanie Kast, Michael Uder Effects of whole-body electromyostimulation with different impulse intensity on blood pressure changes in hyper- and normotensive overweight people. A pilot study
Sara Kaiser, Daniel Schoene, Matthias Kohl, Simon von Stengel, Franz Jakob, Katharina Kerschan-Schindl, Uwe Lange, Friederike Thomasius, Michael Uder, Wolfgang Kemmler Efficacy of Physical Activity and Exercise added to Pharmaceutic Therapy with Denosumab, Romosozumab, Abaloparatide, or Teriparatide in Patients with Osteopenia
Folker Wenzel, M. Hauser, Lars Saemann, Luisa J. Toll Erythropoietin and thrombopoietin release kinetics in clinical settings
André Giesbrecht, Christian Klüß, Gerdy Debeuckelaere, Maria A. Bruno, Folker Wenzel, Matthias Kohl, Filip De Somer, Adrian Bauer Evaluation of university and training standards in clinical perfusion, a European-wide survey
Jose Cordoba-Caballero, James R. Perkins, Federico Garcia-Criado, Diana Gallego, Alicia Navarro-Sanchez, Mireia Moreno-Estelles, Concepcion Garces, Fernando Bonet, Carlos Roma-Mateo, Rocio Toro, Belen Perez, Pascual Sanz, Matthias Kohl, Elena Rojano, Pedro Seoane, Juan A. Ranea Exploring miRNA–target gene pair detection in disease with coRmiT
Thilo O. Kromer, Matthias Kohl, Caroline H. Bastiaenen Factors predicting long-term outcomes following physiotherapy in patients with subacromial pain syndrome : a secondary analysis
D. Rother, Johannes Gehron, F. Brenck, H. Hudel, A. Böning, Folker Wenzel Influence of Covid-19 disease on hemostasis dynamics during extracorporeal membrane oxygenation (ECMO)
Laura Vierbaum, Nathalie Weiss, Patricia Kaiser, Marcel Kremser, Folker Wenzel, Mario Thevis, Ingo Schellenberg, Peter B. Luppa Longitudinal analysis of external quality assessment of immunoassay-based steroid hormone measurement indicates potential for improvement in standardization
Luisa J. Toll, Nathalie Weiss, Laura Vierbaum, Ingo Schellenberg, Mario Thevis, Folker Wenzel Longitudinal evaluation of laboratory results and method precision in worldwide erythropoietin external quality assessments
Jessica Jung-Fittkau, Josef Diebold, Andrea Kruse, Hans-Peter Deigner, Magnus S. Schmidt Measurement of the reaction enthalpy of CO2 in aqueous solutions with thermographic and gravimetric methods
Jessica Jung-Fittkau, Josef Diebold, Andrea Kruse, Hans-Peter Deigner, Magnus S. Schmidt Measurement of the reaction enthalpy of CO2 in aqueous solutions with thermographic and gravimetric methods
Teresa Schätzl, Vanessa Todorow, Lars Kaiser, Helga Weinschrott, Benedikt Schoser, Hans-Peter Deigner, Peter Meinke, Matthias Kohl Meta-analysis towards FSHD reveals misregulation of neuromuscular junction, nuclear envelope, and spliceosome
David Kornberger, Tanja Paatsch, Magnus S. Schmidt, Ulrike Salat New combined absorption/1H NMR method for qualitative and quantitative analysis of PET degradation products
Miriam Beier, Daniel Schoene, Matthias Kohl, Simon von Stengel, Michael Uder, Wolfgang Kemmler Non-Athletic Cohorts Enrolled in Longitudinal Whole-Body Electromyostimulation Trials — An Evidence Map
Yen Hai Le, Daniel Schoene, Matthias Kohl, Simon von Stengel, Michael Uder, Wolfgang Kemmler Outcomes Addressed by Longitudinal Whole-Body Electromyostimulation and Belt Electrode-Skeletal Muscle Electrical Stimulation Trials in Middle Aged-Older Adults - an Evidence Map
Matthias Bollinger, Stefan Bushuven, Michael Bentele, Stefanie Bentele, Slatomir Wenske, David Goertz, Alexander D. Shapeton, Matthias Kohl, Patrick Tralls, Bernhard Kumle Preparedness of German emergency departments for chemical, biological, radiological and nuclear (CBRN) incidents
Oliver Riester, Lars Kaiser, Stefan Laufer, Hans-Peter Deigner Rapid Phenotypic Antibiotics Susceptibility Analysis by a 3D Printed Prototype
Isabel Quint, Jonathan Simantzik, Lars Kaiser, Stefan Laufer, Rene Csuk, David Smith, Matthias Kohl, Hans-Peter Deigner Ready-to-use nanopore platform for label-free small molecule quantification: Ethanolamine as first example
Simon Mayer, Felix Fuchs, Gernot Hipp, Ulrich F. Franke, Matthias Kohl, Folker Wenzel, Christian Wunder, Magdalena Rufa Relationship between Low Oxygen Delivery during Extracorporeal Circulation and Postoperative Acute Kidney Injury after Minimally Invasive Cardiac Surgery
Simon von Stengel, Michael Fröhlich, Oliver Ludwig, Christoph Eifler, Joshua Berger, Heinz Kleinöder, Florian Micke, Bernd Wegener, C. Zinner, Frank C. Mooren, Marc Teschler, Andre Filipovic, S. Müller, K. England, J. Vatter, S. Authenrieth, Matthias Kohl, Wolfgang Kemmler Revised contraindications for the use of non-medical WB-electromyostimulation. Evidence-based German consensus recommendations
Oliver Riester, Stefan Laufer, Roland Mertelsmann, Hans-Peter Deigner Sensors for Antibiotics Susceptibility Testing — Recent Advances
Matthias Kohl, Frank Münch Statistik Teil 10 : Wichtige Tests für nominale Merkmale
Matthias Kohl, Frank Münch Statistik Teil 9: Die 1-Weg ANOVA
B. Kelmendi, Stephanie Kast, Simon von Stengel, Matthias Kohl, F. W. Roemer, Michael Uder, Wolfgang Kemmler, Robert Kob The Effect of Whole-Body Electromyostimulation on Inflammatory Biomarkers and Adipokines in Overweight to Obese Adults with Knee Osteoarthritis : a Randomized Controlled Study
Simone Rentschler, Max Borgolte, Rene Csuk, Stefan Laufer, Hans-Peter Deigner Toward more sustainable enzyme reactions: enhancing kinetics by polydimethylacrylamide implementation

2023

Simon von Stengel, Matthias Kohl, Franz Jakob, Katharina Kerschan-Schindl, Uwe Lange, Stefan Peters, Friederike Thomasius, Michael Uder, Mahdieh Shojaa, Wolfgang Kemmler (Trainings-)Methodische Empfehlungen eines körperlichen Trainings zur Verbesserung der Knochenfestigkeit
Suihong Liu, Lijia Cheng, Yakui Liu, Haiguang Zhang, Yongteng Song, Jeong-Hui Park, Khandmaa Dashnyam, Jung-Hwan Lee, Fouad Al-Hakim Khalak, Oliver Riester, Zheng Shi, Serge Ostrovidov, Hirokazu Kaji, Hans-Peter Deigner, Jose Luis Pedraz, Jonathan C. Knowles, Qingxi Hu, Hae-Won Kim, Murugan Ramalingam 3D Bioprinting tissue analogs: Current development and translational implications
Cecile Fischer, Franz Jakob, Matthias Kohl, Stephanie Kast, Simon von Stengel, Katharina Kerschan-Schindl, Uwe Lange, Friederike Thomasius, Stefan Peters, Michael Uder, Wolfgang Kemmler Additive Effects of Exercise and Vitamin D Supplementation (with and without Calcium) on Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis
Benjamin Brandes, Sophie Hoenke, Christian Schultz, Hans-Peter Deigner, Rene Csuk Converting bile acids into mitocans
Leonard A. Jason, Uta Behrends, Svetlana Blitshteyn, Patrick Gerner, Bettina Grande, Tilman Grande, Sabine Hammer, Kathryn Hoffmann, Matthias Kohl, Herbert Renz-Polster, Carmen Scheibenbogen, Michael Stingl, Eva Untersmayr, Mark Vink, Francisco Westermeier, Brian M. Hughes Die Übersicht zur aktuellen Evidenz ignoriert die aktuelle Evidenz : Leserbrief
Matthias Bollinger, Nadja Frere, Alexander D. Shapeton, Weronika Schary, Matthias Kohl, Clemens Kill, Joachim Riße Does Prehospital Suspicion of Sepsis Shorten Time to Administration of Antibiotics in the Emergency Department? A Retrospective Study in One University Hospital
Kira Knauer, Oliver Chaudry, Michael Uder, Matthias Kohl, Wolfgang Kemmler, Sebastian Bickelhaupt, Klaus Engelke Effects of High-Intensity Resistance Training on Visceral Adipose Tissue and Abdominal Aortic Calcifications in Older Men with Osteosarcopenia – Results from the FrOST Study
Mahdieh Shojaa, Isabelle Hoffmann, Matthias Kohl, Simon von Stengel, Clemens Becker, Markus Gosch, Franz Jakob, Katharina Kerschan-Schindl, Bernd Kladny, Uwe Lange, Stefan Peters, Daniel Schöne, Cornel Sieber, Friederike Thomasius, Michael Uder, Wolfgang Kemmler Effektivität eines körperlichen Trainings zur Reduktion niedrig-traumatischer und osteoporotischer Hauptfrakturen in Erwachsenen. Systematische Übersichtsarbeit und Meta-Analyse
Daniel Schoene, Michaela Gross, Simon von Stengel, Matthias Kohl, Bernd Kladny, Markus Gosch, Cornel C. Sieber, Stefan Peters, Eva Kiesswetter, Clemens Becker, Wolfgang Kemmler Empfehlungen für ein körperliches Training zur Sturzprävention bei älteren, selbständig lebenden Menschen
Stephanie Kast, Franz Jakob, Matthias Kohl, Simon von Stengel, Katharina Kerschan-Schindl, Uwe Lange, Friederike Thomasius, Wolfgang Kemmler Exercise effects on glucocorticoid induced bone loss in adults: a systematic review and meta-analysis
Ramin Mohebbi, Mahdieh Shojaa, Matthias Kohl, Simon von Stengel, Franz Jakob, Katharina Kerschan-Schindl, Uwe Lange, Stefan Peters, Friederike Thomasius, Michael Uder, Wolfgang Kemmler Exercise training and bone mineral density in postmenopausal women: an updated systematic review and meta-analysis of intervention studies with emphasis on potential moderators
Sven Kleine Bardenhorst, Emanuele Cereda, Marco Severgnini, Michela Barichella, Gianni Pezzoli, Ali Keshavarzian, Alessandro Desideri, Daniele Pietrucci, Velma T. Aho, Filip Scheperjans, Falk Hildebrand, Severin Weis, Markus Egert, Andre Karch, Marius Vital, Nicole Rübsamen Gut microbiota dysbiosis in Parkinson's disease — a systematic review and pooled analysis
Sophia Jungmann, Michael Hettchen, Matthias Kohl, Wolfgang Kemmler Impact of 3 months of detraining after high intensity exercise on menopause-related symptoms in early postmenopausal women – results of the randomized controlled actlife project
Murugan Ramalingam, Abinaya Jaisankar, Lijia Cheng, Sasirekha Krishnan, Liang Lan, Anwarul Hassan, Hilal Turkoglu Sasmazel, Hirokazu Kaji, Hans-Peter Deigner, Jose L. Pedraz, Hae-Won Kim, Zheng Shi, Giovanna Marrazza Impact of nanotechnology on conventional and artificial intelligence-based biosensing strategies for the detection of viruses
Lars Saemann, Adian-Iustin Georgevici, Fabio Hoorn, Nitin Gharpure, Gabor Veres, Sevil Korkmaz-Icöz, Matthias Karck, Andreas Simm, Folker Wenzel, Gabor Szabo Improving Diastolic and Microvascular Function in Heart Transplantation with Donation after Circulatory Death
Sebastian Willert, Simon von Stengel, Matthias Kohl, Franz Jakob, Katharina Kerschan-Schindl, Uwe Lange, Stefan Peters, Friederike Thomasius, Wolfgang Kemmler Körperliches Training und Frakturprävention. Trainingsinhaltliche Empfehlungen zur Verbesserung der Knochenfestigkeit
Mark Vink, Tilman Grande, Matthias Kohl Letter to the Editor Regarding Fleischer et al. Neurological Study Does Not Provide Any Evidence that Long COVID is Psychosomatic
Isabel Quint, Jonathan Simantzik, Lars Kaiser, Stefan Laufer, Rene Csuk, David Smith, Matthias Kohl, Hans-Peter Deigner Ready-to-use nanopore platform for ethanolamine quantification using an aptamer-based strand displacement assay
Gabriel E. Wagner, Johanna Dabernig-Heinz, Michaela Lipp, Adriana Cabal, Jonathan Simantzik, Matthias Kohl, Martina Scheiber, Sabine Lichtenegger, Ralf Ehricht, Eva Leitner, Werner Ruppitsch, Ivo Steinmetz Real-Time Nanopore Q20+ Sequencing Enables Extremely Fast and Accurate Core Genome MLST Typing and Democratizes Access to High-Resolution Bacterial Pathogen Surveillance
Christoph Kalka, Lisa Lippik, Folker Wenzel, Hanno Hoppe, Hak-Hong Keo, Christian Heiss, Nicolas Diehm Role of Lp(a) in patients with erectile dysfunction undergoing angioplasty for symptomatic pelvic artery disease
Filip Paskali, Jonathan Simantzik, Angela Dieterich, Matthias Kohl Specification of Neck Muscle Dysfunction through Digital Image Analysis Using Machine Learning
Matthias Kohl, Frank Münch Statistik Teil 5: Kontingenzkoeffizienten
Matthias Kohl, Frank Münch Statistik Teil 6: Methodenvergleiche
Matthias Kohl, Frank Münch Statistik Teil 7: Statistische Signifikanztests
Matthias Kohl, Frank Münch Statistik Teil 8: t-Tests und Alternativen
Simon von Stengel, Matthias Kohl, Franz Jakob, Katharina Kerschan-Schindl, Uwe Lange, Stefan Peters, Friederike Thomasius, Michael Uder, Michael Fröhlich, Daniel Schöne, Wolfgang Kemmler, Mahdieh Shojaa Stellenwert ausgewählter Trainingsprinzipien innerhalb eines körperlichen Trainings zur Frakturprophylaxe
Bassam Abu Thaher, Ihab Al-Masri, Kanan Wahedy, Rami Morjan, Saeb Aliwaini, Iman M. Al atter, Aayat A. Elmabhouh, Areej khaled AL ibwaini, Basem Queshta, Claus Jacob, Hans-Peter Deigner, Saba L. Alkhaldi Synthesis and bioassay of 3-Aryl -1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]- triazin-4(3H)-ones as anti-cancer agents
Eileen Schinzel, Stephanie Kast, Matthias Kohl, Simon von Stengel, Franz Jakob, Katharina Kerschan-Schindl, Bernd Kladny, Uwe Lange, Stefan Peters, Friederike Thomasius, Jürgen Clausen, Michael Uder, Wolfgang Kemmler The effect of aquatic exercise on bone mineral density in older adults. A systematic review and meta-analysis
Ramin Mohebbi, Simon von Stengel, Matthias Kohl, Franz Jakob, Katharina Kerschan-Schindl, Uwe Lange, Stefan Peters, Daniel Schöne, Friederike Thomasius, Clemens Becker, Bernd Kladny, Wolfgang Kemmler Trainingsziele und Risikokategorisierung im Spannungsfeld körperliches Training und Frakturprophylaxe: Ansatzpunkte für individualisierte Trainingsprogramme
Simon von Stengel, Daniel Schöne, Matthias Kohl, Clemens Becker, Markus Gosch, Franz Jakob, Katharina Kerschan-Schindl, Bernd Kladny, Uwe Lange, Stefan Peters, Cornel Sieber, Friederike Thomasius, Michael Uder, Mahdieh Shojaa, Wolfgang Kemmler Zusammengefasste Empfehlungen für ein körperliches Training zur Frakturprophylaxe postmenopausaler Frauen und Männer 45 Jahre und älter

2022

Max Borgolte, Isabel Quint, Lars Kaiser, Rene Csuk, Hans-Peter Deigner A Fluorescence-Based Competitive Antibody Binding Assay for Kynurenine, a Potential Biomarker of Kidney Transplant Failure
Lars Saemann, Sven Maier, Lisa Rösner, Matthias Kohl, Christine Schmucker, Christian Scherer, Georg Trummer, Friedhelm Beyersdorf, Christoph Benk A Systematic Review with Meta-Analysis Investigating the Impact of Targeted Perfusion Parameters during Extracorporeal Cardiopulmonary Resuscitation in Out-of-Hospital and Inhospital Cardiac Arrest
Axel Franz, Hacer Yapicioglu-Yildizdas, Erdal Taskin, Akan Yaman, Yalcin Celik, Huseyin Simsek, Serif Hamitoglu, Nesil Aydinol, Elif Keles, Matthias Keller, Manon Benders, Floris Groenendaal, Kim Anninck, Lena Hellström-Westas, Ola Saugstad, Neil Marlow, Hans-Peter Deigner, Matthias Kohl, Ron Meyer, Achim Plum, Carola Steins-Rang, Peter Bartmann Asphyxia Associated Metabolite Biomarker Investigation (AAMBI). Short-term clinical outcomes and at the age of 22 to 42 months
Marie Kozubek, Sophie Hoenke, Hans-Peter Deigner, Rene Csuk Betulinic acid and glycyrrhetinic acid derived piperazinyl spacered rhodamine B conjugates are highly cytotoxic and necrotic
Angelika Czajkowska, Defne I. Dayi, Helga Weinschrott, Hans-Peter Deigner, Magnus S. Schmidt Chemical decarboxylation kinetics and identification of amino acid standards by benchtop NMR spectroscopy
Jessica Jung, Lars Kaiser, Hans-Peter Deigner, Magnus S. Schmidt Continuous synthesis of bromoalkyl glycosides by Fischer glycosylation in a microreactor
Alexandra Zorin, Lukas Klenk, Tonia Mack, Hans-Peter Deigner, Magnus S. Schmidt Current Synthetic Approaches to the Synthesis of Carbasugars from Non-Carbohydrate Sources
Oliver Riester, Stefan Laufer, Hans-Peter Deigner Direct 3D printed biocompatible microfluidics: assessment of human mesenchymal stem cell differentiation and cytotoxic drug screening in a dynamic culture system
Jan Vagedes, Silja Kuderer, Katrin Vagedes, Henrik Szöke, Matthias Kohl, Stefanie Joos, Florian Beissner, Ursula Wolf Do Chest Compresses with Mustard or Ginger Affect Warmth Regulation in Healthy Adults? A Randomized Controlled Trial
Silja Kuderer, Katrin Vagedes, Henrik Szöke, Matthias Kohl, Stefanie Joos, Peter W. Gündling, Jan Vagedes Do ginger footbaths improve symptoms of insomnia more than footbaths with warm water only? – A randomized controlled study
Severin Weis, Susanne Jacksch, Marius Welkerling, Magnus S. Schmidt, Markus Egert Do it yourself! – Initial experiences with self-synthesized CsTFA for RNA-SIP analyses
Fabienne Flessa, Wolfgang Babel, Alexander Kehl, Gerhard Rambold, Matthias Kohl Effect of sap-feeding insects, plant characteristics, and weather parameters on sooty moulds in the temperate zone
Stephanie Kast, Mahdieh Shojaa, Matthias Kohl, Simon von Stengel, Markus Gosch, Franz Jakob, Katharina Kerschan-Schindl, Bernd Kladny, Nicole Klöckner, Uwe Lange, Stefan Middeldorf, Stefan Peters, Daniel Schoene, Cornel Sieber, Friederike Thomasius, Michael Uder, Wolfgang Kemmler Effects of different exercise intensity on bone mineral density in adults: a comparative systematic review and meta-analysis
Clara Born, Franz Jakob, Mahdieh Shojaa, Matthias Kohl, Simon von Stengel, Katharina Kerschan-Schindl, Uwe Lange, Friederike Thomasius, Wolfgang Kemmler Effects of hormone therapy and exercise on bone mineral density in healthy women – A systematic review and meta-analysis
Christopher Klotz, Franz Jakob, Matthias Kohl, Simon von Stengel, Uwe Lange, Friederike Thomasius, Katharina Kerschan-Schindl, Michael Uder, Wolfgang Kemmler Effekt von additivem körperlichem Training zur Bisphosphonat-Therapie auf die Knochendichte: Eine systematische Übersichtsarbeit und Meta-Analyse
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl Effekte körperlichen Trainings auf osteoporotische Hauptfrakturen bei Menschen in mittlerem-hohen Lebensalter. Eine systematische Übersicht und Meta-Analyse
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl Effekte unterschiedlicher Reizintensität auf den Knochenmineralgehalt bei Erwachsenen – systematischer Review und Meta-Analyse
Matthias Kohl Einführung in die statistische Datenanalyse mit R
Isabelle Hoffmann, Mahdieh Shojaa, Matthias Kohl, Simon von Stengel, Clemens Becker, Markus Gosch, Franz Jakob, Katharina Kerschan-Schindl, Bernd Kladny, Jürgen Clausen, Uwe Lange, Stefan Middeldorf, Stefan Peters, Daniel Schoene, Cornel Sieber, Reina Tholen, Friederike Thomasius, Heike A. Bischoff-Ferrari, Michael Uder, Wolfgang Kemmler Exercise Reduces the Number of Overall and Major Osteoporotic Fractures in Adults. Does Supervision Make a Difference? Systematic Review and Meta-Analysis
Isabelle Hoffmann, Matthias Kohl, Simon von Stengel, Franz Jakob, Katharina Kerschan-Schindl, Uwe Lange, Stefan Peters, Daniel Schoene, Cornel Sieber, Friederike Thomasius, Heike A. Bischoff-Ferrari, Michael Uder, Wolfgang Kemmler Exercise and the prevention of major osteoporotic fractures in adults: a systematic review and meta-analysis with special emphasis on intensity progression and study duration
Toni C. Denner, Sophie Hoenke, Oliver Kraft, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk Hydroxyethylamide substituted triterpenoic acids hold good cytotoxicity for human tumor cells
Matthias Kohl Introduction to statistical data analysis with R
Ahmed A. Salem, Kira Trares, Matthias Kohl, Eugene Jansen, Hermann Brenner, Ben Schöttker Long-term effects of smoking on serum concentrations of oxidative stress biomarkers: Results of a large, population-based cohort study
Prisca Gebrayel, Carole Nicco, Souhaila Al Khodor, Jaroslaw Bilinski, Elisabetta Caselli, Elena M. Comelli, Markus Egert, Cristina Giaroni, Tomasz M. Karpinski, Igor Loniewski, Agata Mulak, Julie Reygner, Paulina Samczuk, Matteo Serino, Mariusz Sikora, Annalisa Terranegra, Marcin Ufnal, Romain Villeger, Chantal Pichon, Peter Konturek, Marvin Edeas Microbiota medicine: towards clinical revolution
Lena Brandau, Susanne Jacksch, Severin Weis, Sylvia Schnell, Markus Egert Minority report: small-scale metagenomic analysis of the non-bacterial kitchen sponge microbiota
Weronika Schary, Filip Paskali, Simone Rentschler, Christoph Ruppert, Gabriel E. Wagner, Ivo Steinmetz, Hans-Peter Deigner, Matthias Kohl Open-Source, Adaptable, All-in-One Smartphone-Based System for Quantitative Analysis of Point-of-Care Diagnostics
Lars Saemann, Matthias Kohl, Gabor Veres, Sevil Korkmaz-Icöz, Anne Großkopf, Matthias Karck, Andreas Simm, Folker Wenzel, Gabor Szabo Prediction Model for Contractile Function of Circulatory Death Donor Hearts Based on Microvascular Flow Shifts During Ex Situ Hypothermic Cardioplegic Machine Perfusion
Lena Brandau, Severin Weis, Maximilian Weyland, Fabian K. Berger, Sylvia Schnell, Karl-Herbert Schäfer, Markus Egert RNA-based stable isotope probing provides no indication for rapid α-synuclein assimilation by murine gut bacteria
Matthias Bollinger, Petra Saile, Alexander D. Shapeton, Matthias Kohl, Bernhard Kumle Sensitivity of severe acute respiratory syndrome coronavirus type 2 rapid antigen point-of-care tests in vaccinated patients
Markus Blaess, Oliver Sommerfeld, Rene Csuk, Hans-Peter Deigner Small molecules targeting endolysosomal acidification and signaling in sepsis and severe SARS-CoV-2 infection/COVID-19
Filip Paskali, Angela Dieterich, Matthias Kohl Specification of neck muscle dysfunction through digital image analysis using machine learning
Matthias Kohl, Frank Münch Statistik Teil 1: Der Box- und Whisker-Plot
Matthias Kohl, Frank Münch Statistik Teil 2: Datenorganisation mit Tabellenkalkulationsprogrammen
Matthias Kohl, Frank Münch Statistik Teil 3: Konfidenzintervalle
Matthias Kohl, Frank Münch Statistik Teil 4: Korrelationen
Oliver Riester, Pia Burkhardtsmaier, Yuna Gurung, Stefan Laufer, Hans-Peter Deigner, Magnus S. Schmidt Synergy of R‑(–)carvone and cyclohexenone‑based carbasugar precursors with antibiotics to enhance antibiotic potency and inhibit biofilm formation
Benjamin Brandes, Sophie Hoenke, Niclas Starke, Immo Serbian, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk Synthesis and cytotoxicity of apoptosis-inducing N-heterocyclic triterpene amides
Marie Kozubek, Sophie Hoenke, Theresa Schmidt, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk Synthesis and cytotoxicity of betulin and betulinic acid derived 30-oxo-amides
Max Borgolte, Oliver Riester, Isabel Quint, Felix Blendinger, Volker Bucher, Stefan Laufer, Rene Csuk, Luca Scotti, Hans-Peter Deigner Synthesis of a biocompatible benzophenone-substituted chitosan hydrogel as novel coating for PEEK with extraordinary strong antibacterial and anti-biofilm properties
Anna-Lena Zitzmann, Mahdieh Shojaa, Stephanie Kast, Matthias Kohl, Simon von Stengel, Diana Borucki, Markus Gosch, Franz Jakob, Katharina Kerschan-Schindl, Bernd Kladny, Uwe Lange, Stefan Middeldorf, Stefan Peters, Daniel Schoene, Cornel Sieber, Friederike Thomasius, Michael Uder, Wolfgang Kemmler The effect of different training frequency on bone mineral density in older adults. A comparative systematic review and meta-analysis
Jan Vagedes, Silja Kuderer, Eduard Helmert, Katrin Vagedes, Matthias Kohl, Henrik Szöke, Florian Beissner, Stefanie Joos, Frank Andrasik The immediate effect of Sinapis nigra and Zingiber officinale as thermogenic substances during footbaths: A Randomized Controlled Cross-over Trial
Niels V. Heise, Jördis-Ann Schüler, Torje E. Orlamünde, Benjamin Brandes, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk Triterpenoid cholinesterase inhibitors that might improve gait disturbances in Parkinson's disease patients
Susanne Jacksch, Christoph König, Dominik Kaiser, Lars Kaiser, Mirko Weide, Sylvia Schnell, Hans-Peter Deigner, Markus Egert Using OMICS-technologies to unravel the mystery of malodour formation in washing machines and on washed laundry
Frank Münch, A. Purbojo, Folker Wenzel, Matthias Kohl, S. Dittrich, M. Rauh, R. Zimmermann, N. Kwapil Verbesserte Qualität gelagerter Erythrozytenkonzentrate durch maschinelle Autotransfusion

2021

Jonas Schmidt, Sandro Berghaus, Frithjof Blessing, Folker Wenzel, Holger Herbeck, Josef Blessing, Peter Schierack, Stefan Rödiger, Dirk Roggenbuck A semi-automated, isolation-free, high-throughput SARS-CoV-2 reverse transcriptase (RT) loop-mediated isothermal amplification (LAMP) test
Benjamin Brandes, Sophie Hoenke, Michael Türk, Björn Weber, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk A unified strategy for the synthesis of amorfrutins A and B and evaluation of their cytotoxicity
Marie Kozubek, Linda Höhlich, Sophie Hoenke, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk Apoptotic activity of substituted 3-O-acetyl-betulinic acid benzylamides
Severin Weis, Alexandra Meisner, Andreas Schwiertz, Marcus M. Unger, Anouck Becker, Klaus Faßbender, Sylvia Schnell, Karl-Herbert Schäfer, Markus Egert Association between Parkinson’s disease and the faecal eukaryotic microbiota
Abid A. Khan, Sana Khan, Suhaib Khan, Simone Rentschler, Stefan Laufer, Hans-Peter Deigner Biosynthesis of iron oxide magnetic nanoparticles using clinically isolated Pseudomonas aeruginosa
Oliver Riester, Max Borgolte, Rene Csuk, Hans-Peter Deigner Challenges in Bone Tissue Regeneration: Stem Cell Therapy, Biofunctionality and Antimicrobial Properties of Novel Materials and Its Evolution
Wolfgang Kemmler, Daniel Schoene, Matthias Kohl, Simon von Stengel Changes in Body Composition and Cardiometabolic Health After Detraining in Older Men with Osteosarcopenia: 6-Month Follow-Up of the Randomized Controlled Franconian Osteopenia and Sarcopenia Trial (FrOST) Study
Michael Hettchen, Simon von Stengel, Matthias Kohl, Marie H. Murphy, Mahdieh Shojaa, Mansour Ghasemikaram, Laura Bragonzoni, Francesco Benvenuti, Claudio Ripamonti, Maria G. Benedetti, Mikko Julin, Tapani Risto, Wolfgang Kemmler Changes in Menopausal Risk Factors in Early Postmenopausal Osteopenic Women After 13 Months of High-Intensity Exercise: The Randomized Controlled ACTLIFE-RCT
Jan Vagedes, Silja Kuderer, Katrin Vagedes, Henrik Szöke, Matthias Kohl, Ursula Wolf Chest Compresses with Ginger or Mustard Affect Warmth Regulation in Healthy Adults - A Randomized Co
Mostafa Mahmoud, Christoph Ruppert, Simone Rentschler, Stefan Laufer, Hans-Peter Deigner Combining aptamers and antibodies: lateral flow quantification for thrombin and interleukin-6 with smartphone readout
Birgit Fritz, Edita Paschko, Wayne Young, Daniel Böhringer, Siegfried Wahl, Focke Ziemssen, Markus Egert Comprehensive Compositional Analysis of the Slit Lamp Bacteriota
Theresa Schmidt, Niels Heise, Kurt Merzweiler, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk Concise Synthesis of Both Enantiomers of Pilocarpine
Susanne Jacksch, Huzefa Zohra, Mirko Weide, Sylvia Schnell, Markus Egert Cultivation-Based Quantification and Identification of Bacteria at Two Hygienic Key Sides of Domestic Washing Machines
Weronika Schary, Filip Paskali, Jonathan Simantzik, Matthias Kohl Data Science für die Lebenswissenschaften
Saeb Aliwaini, Bassam Abu Thaher, Ihab Al-Masri, Nabil Shurrab, Said El-Kurdi, Dieter Schollmeyer, Basem Qeshta, Mariam Ghunaim, Rene Csuk, Stefan Laufer, Lars Kaiser, Hans-Peter Deigner Design, Synthesis and Biological Evaluation of Novel Pyrazolo[1,2,4]triazolopyrimidine Derivatives as Potential Anticancer Agents
Mansour Ghasemikaram, Klaus Engelke, Matthias Kohl, Simon von Stengel, Wolfgang Kemmler Detraining Effects on Muscle Quality in Older Men with Osteosarcopenia. Follow-Up of the Randomized Controlled Franconian Osteopenia and Sarcopenia Trial (FrOST)
Wolfgang Kemmler, Michael Hettchen, Matthias Kohl, Marie Murphy, Laura Bragonzoni, Mikko Julin, Tapani Risto, Simon von Stengel Detraining Effects on Musculoskeletal Parameters in Early Postmenopausal Osteopenic Women: 3-Month Follow-Up of the Randomized Controlled ACTLIFE Study
Wolfgang Kemmler, Matthias Kohl, Michael Fröhlich, Daniel Schoene, Simon von Stengel Detraining effects after 18 months of high intensity resistance training on osteosarcopenia in older men—Six-month follow-up of the randomized controlled Franconian Osteopenia and Sarcopenia Trial (FrOST)
Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Rene Csuk, Hans-Peter Deigner Drug triggered pruritus, rash, papules, and blisters – is AGEP a clash of an altered sphingolipid-metabolism and lysosomotropism of drugs accumulating in the skin?
Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Rene Csuk, Hans-Peter Deigner Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19
Mansour Ghasemikaram, Oliver Chaudry, Armin M. Nagel, Michael Uder, Franz Jakob, Wolfgang Kemmler, Matthias Kohl, Klaus Engelke Effects of 16 months of high intensity resistance training on thigh muscle fat infiltration in elderly men with osteosarcopenia
Michael Hettchen, Simon von Stengel, Matthias Kohl, Marie H. Murphy, Mahdieh Shojaa, Mansour Ghasemikaram, Laura Bragonzoni, Francesco Benvenuti, Claudio Ritpamonti, Gracia Benedetti, Mikko Julin, Tapani Risto, Wolfgang Kemmler Effects of High-Intensity Aerobic Exercise and Resistance Training on Cardiometabolic Risk in Early-Postmenopausal Women
Jan Vagedes, Silja Kuderer, Katrin Vagedes, Henrik Szöke, Matthias Kohl Effects of footbaths with ginger powder on sleep quality in insomnia
Wolfgang Kemmler, Mahdieh Shojaa, James Steele, Joshua Berger, Michael Fröhlich, Daniel Schoene, Simon von Stengel, Heinz Kleinöder, Matthias Kohl Efficacy of Whole-Body Electromyostimulation (WB-EMS) on Body Composition and Muscle Strength in Non-athletic Adults. A Systematic Review and Meta-Analysis
Said El-Kurdi, Bassam Abu Thaher, Kanan M. Wahedy, Dieter Schollmeyer, Levin Nopper, Oliver Riester, Hans-Peter Deigner Efficient Synthesis and X-ray Structure of [1,2,4]Triazolo[4,3-a]pyridines via Oxidative Cyclization Using N-Chlorosuccinimide (NCS)
Simone Rentschler, Lars Kaiser, Hans-Peter Deigner Emerging Options for the Diagnosis of Bacterial Infections and the Characterization of Antimicrobial Resistance
Michelle Mages, Mahdieh Shojaa, Matthias Kohl, Simon von Stengel, Clemens Becker, Markus Gosch, Franz Jakob, Katharina Kerschan-Schindl, Bernd Kladny, Nicole Klöckner, Uwe Lange, Stefan Middeldorf, Stefan Peters, Daniel Schoene, Cornel C. Sieber, Reina Tholen, Friederike Thomasius, Michael Uder, Wolfgang Kemmler Exercise Effects on Bone Mineral Density in Men
Teresa Schätzl, Lars Kaiser, Hans-Peter Deigner Facioscapulohumeral muscular dystrophy: genetics, gene activation and downstream signalling with regard to recent therapeutic approaches: an update
Walburga Dieterich, Esther Tietz, Matthias Kohl, Peter C. Konturek, Timo Rath, Markus F. Neurath, Yurdagül Zopf Food Intolerance of Unknown Origin: Caused by Mucosal Inflammation? A Pilot Study
Christian K. Desiderato, Steffen Sachsenmaier, Kirill V. Ovchinnikov, Jonas Stohr, Susanne Jacksch, Dominique N. Desef, Peter Crauwels, Markus Egert, Dzung B. Diep, Oliver Goldbeck, Christian U. Riedel Identification of Potential Probiotics Producing Bacteriocins Active against Listeria monocytogenes by a Combination of Screening Tools
Lars Saemann, Alina Zubarevich, Folker Wenzel, Jasmin Soethoff, Sivakkanan Loganathan, Sevil Korkmaz-Icöz, Matthias Karck, Gabor Szabo, Gabor Veres Impact of skeletonized harvesting of the internal thoracic artery on intrasternal microcirculation considering preparation quality
Lars Kaiser, Isabel Quint, Rene Csuk, Manfred Jung, Hans-Peter Deigner Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference
Max Borgolte, Oliver Riester, Tereza Kacerova, Simone Rentschler, Magnus S. Schmidt, Susanne Jacksch, Markus Egert, Stefan Laufer, Rene Csuk, Hans-Peter Deigner Methacryloyl-GlcNAc Derivatives Copolymerized with Dimethacrylamide as a Novel Antibacterial and Biocompatible Coating
Lars Saemann, Folker Wenzel, Matthias Kohl, Sevil Korkmaz-Icöz, Fabio Hoorn, Sivakkanan Loganathan, Yuxing Guo, Qingwei Ding, Pengyu Zhou, Gabor Veres, Matthias Karck, Gabor Szabo Monitoring of perfusion quality and prediction of donor heart function during ex-vivo machine perfusion by myocardial microcirculation versus surrogate parameters
Carina Zink-Rückel, Oliver Chaudry, Klaus Engelke, Mansour Ghasemikaram, Matthias Kohl, Michael Uder, Wolfgang Kemmler Once Weekly Whole-Body Electromyostimulation Enhances Muscle Quality in Men: Data of the Randomized Controlled Franconian Electromyostimulation and Golf Study
Carina Zink-Rückel, Matthias Kohl, Sebastian Willert, Simon von Stengel, Wolfgang Kemmler Once-Weekly Whole-Body Electromyostimulation Increases Strength, Stability and Body Composition in Amateur Golfers. A Randomized Controlled Study
Weronika Schary, Filip Paskali, Simone Rentschler, Christoph Ruppert, Gabriel Wagner, Ivo Steinmetz, Hans-Peter Deigner, Matthias Kohl Open-source, Adaptable, All-in-one Smartphone-based System for Quantitative Analysis of Point-of-care Diagnostics
Abid A. Khan, Khanzadi N. Manzoor, Aamir Sultan, Maria Saeed, Mahrukh Rafique, Sameen Noushad, Ayesha Talib, Simone Rentschler, Hans-Peter Deigner Pulling the Brakes on Fast and Furious Multiple Drug-Resistant (MDR) Bacteria
Lars Saemann, Sevil Korkmaz-Icöz, Fabio Hoorn, Gabor Veres, Patricia Kraft, Adrian-lustin Georgevici, Maik Brune, Yuxing Guo, Sivakkanan Loganathan, Folker Wenzel, Matthias Karck, Gabor Szabo Reconditioning of circulatory death hearts by ex-vivo machine perfusion with a novel HTK-N preservation solution
Lars Saemann, Anne Großkopf, Fabio Hoorn, Gabor Veres, Yuxing Guo, Sevil Korkmaz-Icöz, Matthias Karck, Andreas Simm, Folker Wenzel, Gabor Szabo Relationship of Laser-Doppler-Flow and coronary perfusion and a concise update on the importance of coronary microcirculation in donor heart machine perfusion
Nico Laur, Lars Kaiser, Hans-Peter Deigner, Ralf Kinscherf Sequential Analysis of Trace Elements in a Micro Volume Urine Sample Using Inductively Coupled Plasma Mass Spectrometry
Jonas Schmidt, Sandro Berghaus, Frithjof Blessing, Folker Wenzel, Holger Herbeck, Josef Blessing, Peter Schierack, Stefan Rödiger, Dirk Roggenbuck Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort—correlation with disease characteristics
Florian Micke, Anja Weissenfels, Nicolas Wirtz, Simon von Stengel, Ulrike Dörmann, Matthias Kohl, Heinz Kleinöder, Lars Donath, Wolfgang Kemmler Similar Pain Intensity Reductions and Trunk Strength Improvements Following Whole-Body Electromyostimulation vs. Whole-Body Vibration vs. Conventional Back-Strengthening Training in Chronic Non-specific Low Back Pain Patients: A Three-Armed Randomized Controlled Trial
Benjamin Brandes, Jan H. Halz, Kurt Merzweiler, Hans-Peter Deigner, Rene Csuk Synthesis and structure of azelastine-N-oxides
Alexander M. König, Ulrich Köhler, Olaf Hildebrandt, Hans Schwarzbach, Lena Hannemann, Raphael Boneberg, Johannes T. Heverhagen, Andreas H. Mahnken, Malte Keller, Peter H. Kann, Hans-Peter Deigner, Nico Laur, Ralf Kinscherf, Wulf Hildebrandt The Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Skeletal Muscle Lipid Content in Obese and Nonobese Men
Sophie Hoenke, Martin A. Christoph, Sander Friedrich, Niels Heise, Benjamin Brandes, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk The Presence of a Cyclohexyldiamine Moiety Confers Cytotoxicity to Pentacyclic Triterpenoids
Niels Heise, Sophie Hoenke, Vivienne Simon, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk Type and position of linkage govern the cytotoxicity of oleanolic acid rhodamine B hybrids
Jan Vagedes, Silja Kuderer, Eduard Helmert, Matthias Kohl, Florian Beissner, Henrik Szöke, Stefanie Joos, Ursula Wolf Warm Footbaths with Sinapis nigra or Zingiber officinale Enhance Self-Reported Vitality in Healthy Adults More than Footbaths with Warm Water Only: A Randomized, Controlled Trial
Immo Serbian, Erik Prell, Claudia Fischer, Hans-Peter Deigner, Rene Csuk n-Propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-D-glucopyranoside is a good inhibitor for the β-galactosidase from E. coli

2020

Sophie Hoenke, Niels V. Heise, Michael Kahnt, Hans-Peter Deigner, Rene Csuk Betulinic acid derived amides are highly cytotoxic, apoptotic and selective
Markus Blaess, Lars Kaiser, Martin Sauer, Rene Csuk, Hans-Peter Deigner COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks
Matthias Kohl COVID-19: Erwartete Anzahl von Toten und Dunkelziffer in Deutschland
Christoph Ruppert, Lars Kaiser, Lisa Jacob, Stefan Laufer, Matthias Kohl, Hans-Peter Deigner Duplex Shiny app quantification of the sepsis biomarkers C-reactive protein and interleukin-6 in a fast quantum dot labeled lateral flow assay
Wolfgang Kemmler, Mahdieh Shojaa, Matthias Kohl, Daniel Schoene, Simon von Stengel Dynamisches Krafttraining und Knochendichte an der Lendenwirbelsäule postmenopausaler Frauen : Eine Meta-Analyse unter besonderer Berücksichtigung trainingswissenschaftlicher Kriterien
Mahdieh Shojaa, Simon von Stengel, Daniel Schoene, Matthias Kohl, Giuseppe Barone, Laura Bragonzoni, Laura Dallolio, Sofia Marini, Marie H. Murphy, Aoife Stephenson, Minna Mänty, Mikko Julin, Tapani Risto, Wolfgang Kemmler Effect of Exercise Training on Bone Mineral Density in Post-menopausal Women: A Systematic Review and Meta-Analysis of Intervention Studies
Mahdieh Shojaa, Simon von Stengel, Daniel Schoene, Matthias Kohl, Wolfgang Kemmler Effect of different types of exercise on bone mineral density in postmenopausal women: A systematic review and meta-analysis
Wolfgang Kemmler, Matthias Kohl, Simon von Stengel, Daniel Schoene Effect of high-intensity resistance exercise on cardiometabolic health in older men with osteosarcopenia: the randomised controlled Franconian Osteopenia and Sarcopenia Trial (FrOST)
Wolfgang Kemmler, Mahdieh Shojaa, Matthias Kohl, Simon von Stengel Effects of Different Types of Exercise on Bone Mineral Density in Postmenopausal Women: A Systematic Review and Meta-analysis
Wolfgang Kemmler, Matthias Kohl, Franz Jakob, Klaus Engelke, Simon von Stengel Effects of High Intensity Dynamic Resistance Exercise and Whey Protein Supplements on Osteosarcopenia in Older Men with Low Bone and Muscle Mass. Final Results of the Randomized Controlled FrOST Study
Wolfgang Kemmler, Michael Hettchen, Matthias Kohl, Marie H. Murphy, Mahdieh Shojaa, Mansour Ghasemikaram, Laura Bragonzoni, Francesco Benvenuti, Claudio Ripamonti, Gracia Benedetti, Mikko Julin, Tapani Risto, Simon von Stengel Effects of High Intensity Exercise during Early Postmenopause-the Randomized Controlled ACTLIFE-Study
Wolfgang Kemmler, Matthias Kohl, Michael Fröhlich, Franz Jakob, Klaus Engelke, Simon von Stengel, Daniel Schoene Effects of High Intensity Resistance Training on Osteopenia and Sarcopenia parameters in Older Men with Osteosarcopenia – One‐year results of the randomized controlled Franconian Osteopenia and Sarcopenia Trial (FrOST)
Wolfgang Kemmler, Matthias Kohl, Michael Fröhlich, Klaus Engelke, Simon von Stengel, Daniel Schoene Effects of High-Intensity Resistance Training on Fitness and Fatness in Older Men With Osteosarcopenia
Mahdieh Shojaa, Simon von Stengel, Matthias Kohl, Daniel Schoene, Wolfgang Kemmler Effects of dynamic resistance exercise on bone mineral density in postmenopausal women: a systematic review and meta-analysis with special emphasis on exercise parameters
Lars Saemann, Matthias Karck, Sevil Korkmaz-Icöz, Folker Wenzel, Gabor Szabo Ethical Decision Diagrams on Donation After Cardiocirculatory Death Heart Transplantation Considering Organ Preservation Techniques
Birgit Fritz, Karin Schäfer, Melanie März, Siegfried Wahl, Focke Ziemssen, Markus Egert Eye-Catching Microbes—Polyphasic Analysis of the Microbiota on Microscope Oculars Verifies Their Role as Fomites
Wolfgang Kemmler, Markus Weineck, Matthias Kohl, Simon von Stengel, Jürgen Giessing, Michael Fröhlich, Daniel Schoene High Intensity Resistance Exercise Training to Improve Body Composition and Strength in Older Men With Osteosarcopenia. Results of the Randomized Controlled Franconian Osteopenia and Sarcopenia Trial (FrOST)
Michael Tuttor, Simon von Stengel, Matthias Kohl, Michael Lell, Michael Scharf, Michael Uder, Andreas Wittke, Wolfgang Kemmler High Intensity Resistance Exercise Training vs. High Intensity (Endurance) Interval Training to Fight Cardiometabolic Risk Factors in Overweight Men 30–50 Years Old
Nico Laur, Ralf Kinscherf, Karolina Pomytkin, Lars Kaiser, Otto Knes, Hans-Peter Deigner ICP-MS trace element analysis in serum and whole blood
Silja Kuderer, E. Helmert, H. Szöke, Stefanie Joos, Matthias Kohl, J. Svaldi, Florian Beissner, F. Andrasik, Jan Vagedes Increasing Warmth in Adolescents with Anorexia Nervosa: A Randomized Controlled Crossover Trial Examining the Efficacy of Mustard and Ginger Footbaths
Susanne Jacksch, Dominik Kaiser, Severin Weis, Mirko Weide, Stefan Ratering, Sylvia Schnell, Markus Egert Influence of Sampling Site and other Environmental Factors on the Bacterial Community Composition of Domestic Washing Machines
Markus Bläss, Lars Kaiser, Martin Sauer, Hans-Peter Deigner Lysosomotropic Active Compounds — Hidden Protection against COVID-19 / SARS-CoV-2 Infection?
Matthias Kohl MKclass: Statistical Classification
Matthias Kohl MKomics: Omics Data Analysis
Matthias Kohl MKpower: Power Analysis and Sample Size Calculation
Lars Saemann, Yuxing Guo, Qingwei Ding, Pengyu Zhou, Matthias Karck, Gabor Szabo, Folker Wenzel Machine perfusion of circulatory determined death hearts: A scoping review
Lars Kaiser, Helga Weinschrott, Isabel Quint, Markus Blaess, Rene Csuk, Manfred Jung, Matthias Kohl, Hans-Peter Deigner Metabolite Patterns in Human Myeloid Hematopoiesis Result from Lineage-Dependent Active Metabolic Pathways
Susanne Jacksch, Jyothi Thota, Sudarshan Shetty, Hauke Smidt, Sylvia Schnell, Markus Egert Metagenomic Analysis of Regularly Microwave-Treated and Untreated Domestic Kitchen Sponges
Hans-Peter Deigner, Mostafa Mahmoud Method for the detection and quantification of small Molecules and Fluidic platform for performing the same
Sophie Hoenke, Immo Serbian, Hans-Peter Deigner, Rene Csuk Mitocanic Di- and Triterpenoid Rhodamine B Conjugates
Angela Dieterich, Matthias Kohl Nackenschmerzen verstehen mit KI
Folker Wenzel Notions of "coronavirus" from the perspective of a clinical immunologist and medical historian
Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Simone Rentschler, Rene Csuk, Hans-Peter Deigner Rational Drug Repurposing: Focus on Lysosomotropism, Targets in Disease Process, Drug Profile, and Pulmonary Tissue Accumulation in SARS-CoV-2 Infection/COVID-19
Mustafa K. Özcürümez, Andreas Ambrosch, Oliver Frey, Verena Haselmann, Stefan Holdenrieder, Michael Kiehntopf, Michael Neumaier, Michael Walter, Folker Wenzel, Roman Wölfel, Harald Renz SARS-CoV-2 antibody testing—questions to be asked
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl, Nicolas Rohleder, Thomas Bertsch, Cornel C. Sieber, Ellen Freiberger, Robert Kob Safety of a Combined WB-EMS and High-Protein Diet Intervention in Sarcopenic Obese Elderly Men
Birgit Fritz, Melanie März, Severin Weis, Siegfried Wahl, Focke Ziemssen, Markus Egert Site-specific molecular analysis of the bacteriota on worn spectacles
Benjamin Brandes, Lukas Koch, Sophie Hoenke, Hans-Peter Deigner, Rene Csuk The presence of a cationic center is not alone decisive for the cytotoxicity of triterpene carboxylic acid amides
Severin Weis, Sylvia Schnell, Markus Egert Towards Safer-SIP - Effect of formamide on the separation of isotope-labeled and unlabeled Escherichia coli RNA by isopycnic density ultracentrifugation
Susanne Jacksch, Markus Egert Welcome to the jungle : Das Küchenschwamm-Mikrobiom

2019

Janina Herber, Franziska Klotz, Benjamin Frommeyer, Severin Weis, Dietmar Straile, Allison Kolar, Johannes Sikorski, Markus Egert, Michael Dannenmann, Michael Pester A single Thaumarchaeon drives nitrification in deep oligotrophic Lake Constance
Christoph Ruppert, Navneet Phogat, Stefan Laufer, Matthias Kohl, Hans-Peter Deigner A smartphone readout system for gold nanoparticle-based lateral flow assays: application to monitoring of digoxigenin
Mostafa Mahmoud, Stefan Laufer, Hans-Peter Deigner An aptamer based thermofluorimetric assay for ethanolamine
Anja Weissenfels, Nicolas Wirtz, Ulrike Dörmann, Heinz Kleinöder, Lars Donath, Matthias Kohl, Michael Fröhlich, Simon von Stengel, Wolfgang Kemmler Comparison of Whole-Body Electromyostimulation versus Recognized Back-Strengthening Exercise Training on Chronic Nonspecific Low Back Pain: A Randomized Controlled Study
Mostafa Mahmoud, Stefan Laufer, Hans-Peter Deigner Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
Markus Blaess, Hans-Peter Deigner Derailed Ceramide Metabolism in Atopic Dermatitis (AD): A Causal Starting Point for a Personalized (Basic) Therapy
Severin Weis, Andreas Schwiertz, Marcus M. Unger, Anouck Becker, Klaus Faßbender, Stefan Ratering, Matthias Kohl, Sylvia Schnell, Karl-Herbert Schäfer, Markus Egert Effect of Parkinson’s disease and related medications on the composition of the fecal bacterial microbiota
Josefine Hantschel, Severin Weis, Karl-Herbert Schäfer, Michael D. Menger, Matthias Kohl, Markus Egert, Matthias W. Laschke Effect of endometriosis on the fecal bacteriota composition of mice during the acute phase of lesion formation
Michael Hettchen, Katharina Glöckler, Simon von Stengel, Andrea Piechele, Helmut Lötzerich, Matthias Kohl, Wolfgang Kemmler Effects of Compression Tights on Recovery Parameters after Exercise Induced Muscle Damage: A Randomized Controlled Crossover Study
Sebastian Willert, Anja Weissenfels, Matthias Kohl, Simon von Stengel, Michael Fröhlich, Heinz Kleinöder, Daniel Schöne, Marc Teschler, Wolfgang Kemmler Effects of Whole-Body Electromyostimulation on the Energy-Restriction-Induced Reduction of Muscle Mass During Intended Weight Loss
Saskia Mayer, Marie Prechtl, Pia Liebfried, Ron-Patrick Cadeddu, Fabian Stuhldreier, Matthias Kohl, Folker Wenzel, Björn Stork, Sebastian Wesselborg, Peter Proksch, Ulrich Germing, Rainer Haas, Paul Jäger First Results from a Screening of 300 Naturally Occurring Compounds: 4,6-dibromo-2-(2′,4′-dibromophenoxy)phenol, 4,5,6-tribromo-2-(2′,4′-dibromophenoxy)phenol, and 5-epi-nakijinone Q as Substances with the Potential for Anticancer Therapy
Markus Blaess, Hans-Peter Deigner Focusing on derailed cellular ceramide metabolism fosters recovery of atopic dermatitis lesions and psoriasis plaques
Wolfgang Kemmler, Matthias Kohl, Klaus Engelke, Simon von Stengel Körperliches Training zur Frakturprophylaxe des älteren Menschen
Matthias Kohl MKdescr: Descriptive Statistics
Matthias Kohl MKinfer: Inferential Statistics
Markus Blaess, Folker Wenzel, Hans-Peter Deigner Recovery of derailed ceramide metabolism in atopic dermatitis: a successful topical off-label use of amitriptyline combined with linoleic acid
Riccardo Sfriso, Markus Egert, Mathias Gempeler, Rainer Voegeli, Remo Campiche Revealing the secret life of skin : With the microbiome you never walk alone
Rene Csuk, Hans-Peter Deigner The potential of click reactions for the synthesis of bioactive triterpenes
Adrian Monteleone, Weronika Schary, Andreas Fath, Folker Wenzel Validation of an extraction method for microplastics from human materials
Mostafa Mahmoud, Stefan Laufer, Hans-Peter Deigner Visual aptamer-based capillary assay for ethanolamine using magnetic particles and strand displacement
David Scheinost, Maren Lickert, Steven Oettinger, Filip Paskali, Yannik Ehlers, Matthias Kohl, Angela Dieterich Was sind Muskelverspannungen? Annäherung durch ein interdisziplinäres Forschungsprojekt am Beispiel 'chronischer Nackenschmerz'
Wolfgang Kemmler, Regina Straub, Matthias Kohl, Simon von Stengel Zusammenhang zwischen Sarkopenie und Knochendichte – eine Querschnittsuntersuchung mit Männern 72 Jahre + mit Sarkopenie

2018

Birgit Fritz, Anne Jenner, Siegfried Wahl, Christian Lappe, Achim Zehender, Christian Horn, Frithjof Blessing, Matthias Kohl, Focke Ziemssen, Markus Egert A view to a kill? – Ambient bacterial load of frames and lenses of spectacles and evaluation of different cleaning methods
Wolfgang Kemmler, Simon von Stengel, Daniel Schöne, Matthias Kohl Changes of Maximum Leg Strength Indices During Adulthood a Cross-Sectional Study With Non-athletic Men Aged 19–91
Lars Saemann, Folker Wenzel Cutaneous microcirculation during operations with a cardiopulmonary bypass
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl Developing sarcopenia criteria and cutoffs for an older Caucasian cohort – a strictly biometrical approach
Wolfgang Kemmler, Matthias Kohl, Ellen Freiberger, Cornel Sieber, Simon von Stengel Effect of whole-body electromyostimulation and / or protein supplementation on obesity and cardiometabolic risk in older men with sarcopenic obesity: the randomized controlled FranSO trial
Wolfgang Kemmler, Alexander Grimm, Michael Bebenek, Matthias Kohl, Simon von Stengel Effects of Combined Whole-Body Electromyostimulation and Protein Supplementation on Local and Overall Muscle/Fat Distribution in Older Men with Sarcopenic Obesity: The Randomized Controlled Franconia Sarcopenic Obesity (FranSO) Study
J. Vagedes, E. Helmert, S. Kuderer, V. Müller, P. Voege, H. Szőke, J. Valentini, S. Joos, Matthias Kohl, F. Andrasik Effects of Footbaths with Mustard, Ginger, or Warm Water Only on Objective and Subjective Warmth Distribution in Healthy Subjects: A Randomized Controlled Trial
Anja Weissenfels, Marc Teschler, Sebastian Willert, Michael Hettchen, Michael Fröhlich, Heinz Kleinöder, Matthias Kohl, Simon von Stengel, Wolfgang Kemmler Effects of whole-body electromyostimulation on chronic nonspecific low back pain in adults: a randomized controlled study
Wolfgang Kemmler, M. Shojaa, Matthias Kohl, Simon von Stengel Exercise effects on bone mineral density in older men: a systematic review with special emphasis on study interventions
Markus Egert Honor Thy Lodgers? – Structure and Function of the Human Built Environment Microbiome
Elena Herrmann, Wayne Young, Verena Reichert-Grimm, Severin Weis, Christian U. Riedel, Douglas Rosendale, Halina Stoklosinski, Martin Hunt, Markus Egert In Vivo Assessment of Resistant Starch Degradation by the Caecal Microbiota of Mice Using RNA-Based Stable Isotope Probing — A Proof-of-Principle Study
P. Schalk, Matthias Kohl, H. J. Herrmann, R. Schwappacher, M. E. Rimmele, A. Buettner, J. Siebler, M. F. Neurath, Y. Zopf Influence of cancer and acute inflammatory disease on taste perception: a clinical pilot study
Nacneet Phogat, Matthias Kohl, Imran Uddin Interaction of Nanoparticles With Biomolecules, Protein, Enzymes, and Its Applications
Hans-Peter Deigner(Ed.), , Matthias Kohl(Ed.) Precision Medicine: Tools and Quantitative Approaches
Markus Egert, Severin Weis, Sylvia Schnell RNA-based stable isotope probing (RNA-SIP) to unravel intestinal host-microbe interactions
Matthias Kohl, Bernhard Spangl, Sascha Desmettre, Eugen Massini, Mykhailo Pupashenko, Daria Pupashenko, Gerald Kroisandt, Peter Ruckdeschel RobAStRDA: Interpolation Grids for Packages of the 'RobASt' - Family of Packages
Nataliya Horbenko, Bernhard Spangl, Sascha Desmettre, Eugen Massini, Daria Pupashenko, Gerald Kroisandt, Matthias Kohl, Peter Ruckdeschel RobExtremes: Optimally Robust Estimation for Extreme Value Distributions
Stephan Vilgis, Hans-Peter Deigner Sequencing in Precision Medicine
Lars Kaiser, Julia Weisser, Matthias Kohl, Hans-Peter Deigner Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection
Sowmya S. Perumbakkam, Matthias Kohl Statistical Learning in Precision Medicine

2017

Wayne Dawson, Jens Hör, Markus Egert, Mark van Kleunen, Michael Pester A small number of low-abundance bacteria dominate plant species-specific responses during rhizosphere colonisation
Ha-Yeun Chung, Anna S. Kollmey, Andrea Schrepper, Matthias Kohl, Markus Bläss, Sebastian N. Stehr, Amelie Lupp, Markus H. Gräler, Ralf A. Claus Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction
Lars Saemann, Karin Lachner, Folker Wenzel Cardiac frequency and cutaneous microcirculation during and after exercising in the view of physical condition
Elena Herrmann, Wayne Young, Douglas Rosendale, Ralf Conrad, Christian U. Riedel, Markus Egert Determination of Resistant Starch Assimilating Bacteria in Fecal Samples of Mice by In vitro RNA-Based Stable Isotope Probing
Elena Herrmann, Patrick Koch, Christian U. Riedel, Wayne Young, Markus Egert Effect of rotor type on the separation of isotope-labeled and unlabeled Escherichia coli RNA by isopycnic density ultracentrifugation
Wolfgang Kemmler, Anja Weissenfels, Michael Bebenek, Michael Fröhlich, Heinz Kleinöder, Matthias Kohl, Simon von Stengel Effects of Whole-Body Electromyostimulation on Low Back Pain in People with Chronic Unspecific Dorsal Pain: A Meta-Analysis of Individual Patient Data from Randomized Controlled WB-EMS Trials
Anja Weissenfels, Marc Teschler, Simon von Stengel, Matthias Kohl, Wolfgang Kemmler Effects of Whole-Body-Electromyostimulation on Low Back Pain – a Review of the Evidence
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl Exercise Frequency and Fracture Risk in Older Adults—How Often Is Enough?
Wolfgang Kemmler, Matthias Kohl, Simon von Stengel Long-term effects of exercise in postmenopausal women: 16-year results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)
Massimiliano Cardinale, Dominik Kaiser, Tillmann Lüders, Sylvia Schnell, Markus Egert Microbiome analysis and confocal microscopy of used kitchen sponges reveal massive colonization by Acinetobacter, Moraxella and Chryseobacterium species
Markus Bläss, Nelly Bibak, Ralf A. Claus, Matthias Kohl, Gabriel A. Bonaterra, Ralf Kinscherf, Stefan Laufer, Hans-Peter Deigner NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation
R. Lohmüller, A.-S. Gangloff, Folker Wenzel, W. A. Lagreze Optikushypoplasie und septooptische Dysplasie
Matthias Kohl Package mpe: Multiple Primary Endpoints
Andreas Wittke, Simon von Stengel, Michael Hettchen, Michael Fröhlich, Jürgen Giessing, Michael Lell, Michael Scharf, Michael Bebenek, Matthias Kohl, Wolfgang Kemmler Protein Supplementation to Augment the Effects of High Intensity Resistance Training in Untrained Middle-Aged Males: The Randomized Controlled PUSH Trial
Christoph König, Stephanie Tauchnitz, Heike Kunzelmann, Christian Horn, Frithjof Blessing, Matthias Kohl, Markus Egert Quantification and identification of aerobic bacteria in holy water samples from a German environment
Elena Herrmann, Wayne Young, Douglas Rosendale, Verena Reichert-Grimm, Christian U. Riedel, Ralf Conrad, Markus Egert RNA-Based Stable Isotope Probing Suggests Allobaculum spp. as Particularly Active Glucose Assimilators in a Complex Murine Microbiota Cultured In Vitro
Marc Teschler, Alfred Wassermann, Anja Weissenfels, Michael Fröhlich, Matthias Kohl, Michael Bebenek, Simon von Stengel, Wolfgang Kemmler Short-time effect of a single session of intense whole-body electromyostimulation on energy expenditure. A contribution to fat reduction?
Markus Egert, Rainer Simmering, Christian U. Riedel The association of the skin microbiota with health, immunity and disease
David Grundmann, Victor Zevallos, Sarah Lehnerts, Anne Braun, Stephanie Tauchnitz, Severin Weis, Markus Egert, Detlef Schuppan, Karl-Herbert Schäfer The influence of gluten free diet on the enteric nervous system and intestinal microbiota of mice
Wolfgang Kemmler, Anja Weissenfels, Marc Teschler, Sebastian Willert, Michael Bebenek, Mahdieh Shojaa, Matthias Kohl, Ellen Freiberger, Cornel Sieber, Simon von Stengel Whole-body electromyostimulation and protein supplementation favorably affect sarcopenic obesity in community-dwelling older men at risk: the randomized controlled FranSO study

2016

Marc Teschler, Anja Weissenfels, Michael Fröhlich, Matthias Kohl, Michael Bebenek, Simon von Stengel, Wolfgang Kemmler (Very) high creatine kinase (CK) levels after Whole-Body Electromyostimulation. Are there implications for health?
Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Kanan M. Wahedy, Ihab M. Almasri, Rami Y. Morjan, Hans-Peter Deigner 1-(Pyridin-4-yl)-3-(2,4,6-trichlorophenyl)benz- [4,5]imidazo[1,2-d ][1,2,4]triazin-4(3H)-one
Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Hans-Peter Deigner 3-(2,4-Difluorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one
Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Andreas Kortgen, Eva Möller, Karen Felsmann, Jean M. Cavaillon, Orlando Guntinas-Lichius, Olivier Rutschmann, Andriy Ruryk, Matthias Kohl, Britta Wlotzka, Stefan Rußwurm, John C. Marshall, Konrad Reinhart A Transcriptomic Biomarker to Quantify Systemic Inflammation in Sepsis — A Prospective Multicenter Phase II Diagnostic Study
Ha-Yeun Chung, Daniel C. Hupe, Gordon P. Otto, Marcel Sprenger, Alexander C. Bunck, Michael J. Dorer, Clemens L. Bockmeyer, Hans-Peter Deigner, Markus H. Gräler, Ralf A. Claus Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis
Hans-Peter Deigner Bimodal imaging and beyond: Editorial
Basri Gülbakan, Riza Köksal Özgül, Ayse Yüzbasioglu, Matthias Kohl, Hans-Peter Deigner, Meral Özgüc Discovery of biomarkers in rare diseases: innovative approaches by predictive and personalized medicine
Wolfgang Kemmler, Matthias Kohl, Simon von Stengel Effects Of High Intensity Resistance Training Versus Whole-Body Electromyostimulation On Cardio-Metabolic Risk Factors In Untrained Middle Aged Males. A Randomized Controlled Trail
Wolfgang Kemmler, Marc Teschler, Anja Weissenfels, Michael Bebenek, Michael Fröhlich, Matthias Kohl, Simon von Stengel Effects of Whole-Body Electromyostimulation versus High-Intensity Resistance Exercise on Body Composition and Strength: A Randomized Controlled Study
Matthias Kohl Einführung in das Programmieren mit R
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl Exercise frequency and bone mineral density development in exercising postmenopausal osteopenic women. Is there a critical dose of exercise for affecting bone? Results of the Erlangen Fitness and Osteoporosis Prevention Study
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl, Julia Bauer Impact of exercise changes on body composition during the college years - a five year randomized controlled study
Katharina Wittmann, Cornel Sieber, Simon von Stengel, Matthias Kohl, Ellen Freiberger, Franz Jakob, Michael Lell, Klaus Engelke, Wolfgang Kemmler Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: the randomized controlled FORMOsA sarcopenic obesity study
Christoph Sponholz, Katja Matthes, Dina Rupp, Wolf Backaus, Sebastian Klammt, Diana Karailieva, Astrid Bauschke, Utz Settmacher, Matthias Kohl, Mark G. Clemens, Steffen Mitzner, Michael Bauer, Andreas Kortgen Molecular adsorbent recirculating system and single pass albumin dialysis in liver failure -- a prospective randomized cross-over study
Mario Brameshuber, Eva Sevcsik, Benedikt K. Rossboth, Christina Manner, Hans-Peter Deigner, Begüm Peksel, Mária Péter, Zsolt Török, Albin Hermetter, Gerhard J. Schütz Oxidized Phospholipids Inhibit the Formation of Cholesterol-Dependent Plasma Membrane Nanoplatforms
Wolfgang Kemmler, Michael Bebenek, Matthias Kohl, Simon von Stengel Possible different roles of exercise in preventing vertebral and hip fractures: response to comments by Sugiyama et al.
Anja Bramhoff, Günther Giers, Frithjof Blessing, Folker Wenzel Using the mean platelet volume MPV for the quality assessment of apheresis procedures
Wolfgang Kemmler, Simon von Stengel, Marc Teschler, Anja Weissenfels, Michael Bebenek, Matthias Kohl, Ellen Freiberger, C. Bollheimer, S. Goisser, Cornel Sieber, L. Seefried, Franz Jakob, Klaus Engelke Whole-body Electromyostimulation and Sarcopenic Obesity: Results of the randomized controlled FORMOsA-Sarcopenic Obesity Study
Wolfgang Kemmler, Marc Teschler, Anja Weissenfels, Michael Bebenek, Simon von Stengel, Matthias Kohl, Ellen Freiberger, S. Goisser, Franz Jakob, Cornel Sieber, Klaus Engelke Whole-body electromyostimulation to fight sarcopenic obesity in community-dwelling older women at risk. Results of the randomized controlled FORMOsA-sarcopenic obesity study

2015

Mostafa Mahmoud, Hans-Peter Deigner Aptamers in Diagnostics: Replacing or Complementing Antibodies?
Markus Egert, Kerstin Späth, Karoline Weik, Heike Kunzelmann, Christian Horn, Matthias Kohl, Frithjof Blessing Bacteria on smartphone touchscreens in a German university setting and evaluation of two popular cleaning methods using commercially available cleaning products
Wayne Young, Markus Egert, Shalome A. Bassett, Rodrigo Bibiloni Detection of sialic acid-utilising bacteria in a caecal community in culture using RNA-based stable isotope probing
Matthias Kohl Einführung in die statistische Datenanalyse mit R
Wolfgang Kemmler, Matthias Kohl, Michael Bebenek, Simon von Stengel Entwicklung von Übergewicht und Adipositas im jungen Erwachsenenalter – Stellenwert berufsbedingter Veränderungen des Sporttreibens auf Fettmasse, fettfreie Masse und Körpermasse bei Studenten
Wolfgang Kemmler, Michael Bebenek, Matthias Kohl, Simon von Stengel Exercise and fractures in postmenopausal women. Final results of the controlled Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)
Wolfgang Kemmler, Marc Teschler, Anja Weissenfels, Michael Fröhlich, Matthias Kohl, Simon von Stengel Ganzkörper Elektromyostimulation versus HIT-Krafttraining – Einfluss auf Körperzusammensetzung und Muskelkraft
Markus Bläss, Ralf A. Claus, Hans-Peter Deigner HPLC separation and ultrasensitive optical quantification of ceramide species applying 7-(diethylamino)coumarin-3-carbonyl azide derivatisation
Wolfgang Kemmler, Michael Bebenek, Simon von Stengel, Matthias Kohl, Julia Bauer Increases of Cardiometabolic Risk in Young Adults. Impact of Exercise Reductions during the College Years
Matthias Kohl Introduction to statistical data analysis with R
Wolfgang Kemmler, Matthias Kohl, Michael Bebenek, Simon von Stengel Körperliche Belastung und kardiometabolisches Risiko bei jungen Erwachsenen
Wolfgang Kemmler, Michael Bebenek, Matthias Kohl, Simon von Stengel Körperliches Training, Fraktur und Knochendichte: Finale Ergebnisse der Erlanger Fitness und Osteoporose-Präventions-Studie (EFOPS)
Daria Pupashenko, Peter Ruckdeschel, Matthias Kohl L2 Differentiability of Generalized Linear Models
Christoph Ruppert, Matthias Kohl, Lisa Jacob, Hans-Peter Deigner Multiplexing in Bioassays
Gordon P. Otto, Jorge Hurtado-Oliverso, Ha-Yeun Chung, Kristin Knoll, Thomas Neumann, Hans J. Müller, Marco Herbsleb, Matthias Kohl, Maik Sossdorf, Ralf A. Claus, Martin Busch Plasma neutrophil gelatinase-associated lipocalin is primarily related to inflammation during sepsis: A translational approach
Markus Bläss, H.P. Le, Ralf A. Claus, Matthias Kohl, Hans-Peter Deigner Stereospecific Induction of Apoptosis in Tumor Cells via Endogenous C16-Ceramide and Distinct Transcripts

2014

James R. Perkins, Ana Antunes-Martins, Margarita Calvo, John Grist, Werner Rust, Ramona Schmid, Tobias Hildebrandt, Matthias Kohl, Christine Orengo, Stephen B. McMahon, David L. Bennett A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat
Matthias W. Sieber, Madlen Guenther, Nadine Jaenisch, Daniela Albrecht-Eckardt, Matthias Kohl, Otto W. Witte, Christiane Frahm Age-specific transcriptional response to stroke
Torsten Burkholz, Markus Egert, Claus Jacob Elektrochemische Dekontamination leitender Oberflächen: Von grundlegenden Ideen zu neuen Ansätzen
Peter Ruckdeschel, Matthias Kohl General Purpose Convolution Algorithm in S4-Classes by Means of FFT

2013

Matthias Kohl Analyse von Genexpressionsdaten mit R und Bioconductor
Fabienne Flessa, Alexandra Kehl, Matthias Kohl Analysing diversity and community structures using PCR-RFLP: a new software application
T. Peters, A. Ghadiri, Matthias Kohl Betriebliches Gesundheitsmanagement: audiovisuelle Entspannung kann Krankenstand senken
Nayla Jbeily, Iris Suckert, Falk A. Gonnert, Benedikt Acht, Clemens L. Bockmeyer, Sascha D. Grossmann, Markus Bläss, Anja Lüth, Hans-Peter Deigner, Michael Bauer, Ralf A. Claus Hyperresponsiveness of mice defi cient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response
Markus Egert, Heide-Marie Höhne, T. Weber, Rainer Simmering, Bernhard Banowski, Roland Breves Identification of compounds inhibiting the C-S lyase activity of a cell extract from a Staphylococcus sp. isolated from human skin
Ole Bayer, Daniel Schwarzkopf, Torsten Doenst, Deborah Cook, Björn Kabisch, Christoph Schelenz, Michael Bauer, Niels C. Riedemann, Yasser Sakr, Matthias Kohl, Konrad Reinhart, Christiane S. Hartog Perioperative Fluid Therapy With Tetrastarch and Gelatin in Cardiac Surgery — A Prospective Sequential Analysis
Maik Sossdorf, Gordon P. Otto, Katja Menge, Ralf A. Claus, Wolfgang Lösche, Björn Kabisch, Matthias Kohl, Ulrich C. Smolenski, Peter Schlattmann, Konrad Reinhart, Johannes Winning Potential effect of physiotherapeutic treatment on mortality rate in patients with severe sepsis and septic shock: A retrospective cohort analysis
Klaus Pöttgen, Matthias Kohl Propriozeption im Fußball

2012

Matthias Kohl Analysis of Microarray Data
James R. Perkins, Nor Izayu Abdul Rahman, Matthias Kohl Analysis of RT-qPCR data
Matthias Kohl Bounded influence estimation for regression and scale
Ole Bayer, Konrad Reinhart, Matthias Kohl, Björn Kabisch, John Marshall, Yasser Sakr, Michael Bauer, Christiane S. Hartog, Daniel Schwarzkopf, Niels Riedemann Effects of fluid resuscitation with synthetic colloids or crystalloids alone on shock reversal, fluid balance, and patient outcomes in patients with severe sepsis: A prospective sequential analysis
Matthias Kohl Feature Selection in Statistical Classification
Martina Weber, Sandro Lambeck, Nadine Ding, Stefanie Henken, Matthias Kohl, Hans-Peter Deigner, David P. Enot, Ignatius E. Igwe, Lucien Frappart, Michael Kiehntopf, Ralf A. Claus, Thomas Kamradt, Debra Weih, Yoram Vodovotz, David E. Briles, Abiodun D. Ogunniyi, James C. Paton, Ulrich A. Maus, Michael Bauer Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia
Matthias Kohl Performance Measures in Binary Classification
Uwe Kern, Volker Busch, Ruben Müller, Matthias Kohl, Frank Birklein Phantom Limb Pain in Daily Practice—Still a Lot of Work to Do!
James R. Perkins, John M. Dawes, Steve B. McMahon, David L. Bennett, Christine Orengo, Matthias Kohl ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
Ute Stemmer, Zsuzsanna A. Dunai, Daniel Koller, Gabriel Pürstinger, Elfriede Zenzmaier, Hans-Peter Deigner, Elma Aflaki, Dagmar Kratky, Albin Hermetter Toxicity of oxidized phospholipids in cultured macrophages
K.-U. Kern, Matthias Kohl, U. Seifert, T. Schlereth Wirkung von Botulinumtoxin Typ B auf Stumpfschwitzen und Stumpfschmerzen

2011

Christiane S. Hartog, Matthias Kohl, Konrad Reinhart A Systematic Review of Third-Generation Hydroxyethyl Starch (HES 130/0.4) in Resuscitation: Safety Not Adequately Addressed
Matthias Kohl, S. Koch, Matthias Keller, Hans-Peter Deigner Biochips: Bright Future in Clinical Dx?
James Perkins, Matthias Kohl Bioconductor-Package NormqPCR: Functions for normalisation of RT-qPCR data
James Perkins, Matthias Kohl, Nor Izayu Abdul Rahman Bioconductor-Package ReadqPCR: Read qPCR data
Uwe Kern, Matthias Kohl, Ulrich Seifert, Tanja Schlereth Botulinum toxin type B in the treatment of residual limb hyperhidrosis for lower limb amputees: a pilot study.
Matthias Keller, David P. Enot, Mark P. Hodson, Emeka I. Igwe, Hans-Peter Deigner, Justin Dean, Hayde Bolouri, Hendrik Hagberg, Carina Mallard Inflammatory-Induced Hibernation in the Fetus: Priming of Fetal Sheep Metabolism Correlates with Developmental Brain Injury
Nigel Francis, See Heng Wong, Peter Hampson, Keqing Wang, Stephen P. Young, Hans-Peter Deigner, Michael Salmon, Dagmar Scheel-Toellner, Janet M. Lord Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events
Suzanne Perz, Thomas Uhlig, Matthias Kohl, Donald L. Bredle, Konrad Reinhart, Michael Bauer, Andreas Kortgen Low and “supranormal” central venous oxygen saturation and markers of tissue hypoxia in cardiac surgery patients – a prospective observational study.
Hans-Peter Deigner, Michael Bauer, Matthias Kohl Method for in vitro diagnosing sepsis utilizing biomarker composed of more than two different types of endogenous biomolecules
Ole Bayer, Konrad Reinhart, Yasser Sakr, Björn Kabisch, Matthias Kohl, Niels C. Riedemann, Michael Bauer, Utz Settmacher, Khosro Hekmat, Christiane S. Hartog Renal effects of synthetic colloids and crystalloids in patients with severe sepsis – a prospective sequential comparison
Hans-Peter Deigner, Matthias Kohl, Therese Koal, Ignatius E. Igwe, Guido Dallmann, Michael Bauer, David P. Enot Use of bile acids for prediction of an onset of sepsis
Markus Egert, Inke Schmidt, Heide-Marie Höhne, Tim Lachnit, Ruth A. Schmitz, Roland Breves rRNA-based profiling of bacteria in the axilla of healthy males suggests right left asymmetry in bacterial activity

2010

Markus Egert, Irmgard Schmidt, Kevin Bussey, Roland Breves A glimpse under the rim – the composition of microbial biofilm communities in domestic toilets
Julien B. Landré, Markus Bläss, Matthias Kohl, Tina Schlicksbier, Andriy Ruryk, Ralf Kinscherf, Ralf A. Claus, Albin Hermetter, Matthias Keller, Michael Bauer, Hans-Peter Deigner Addressable bipartite molecular hook (ABMH): Immobilized hairpin probes with sensitivity below 50 fM
Ralf A. Claus, Gordon P. Otto, Hans-Peter Deigner, Michael Bauer Approaching Clinical Reality: Markers for Monitoring Systemic Inflammation and Sepsis
Therese Koal, Hans-Peter Deigner Challenges in Mass Spectrometry Based Targeted Metabolomics
Michael Urban, David P. Enot, Guido Dallmann, Lisa Körner, Verena Forcher, Peter Enoh, Therese Koal, Matthias Keller, Hans-Peter Deigner Complexity and pitfalls of mass spectrometry-based targeted metabolomics in brain research
Hans-Peter Deigner, Ancha Baranova Current Methods and Perspectives in Biomarker Discovery: Editorial
Matthias Kohl Development and Validation of Predictive Molecular Signatures
Uwe Kern, Matthias Kohl, Ralph T. Kiefer Lidocain-Pflaster zur Therapie neuropathischer und nichtneuropathischer Schmerzen
Ronnaug Solberg, David P. Enot, Hans-Peter Deigner, Therese Koal, Sabine Scholl-Bürgi, Ola D. Saugstad, Matthias Keller Metabolomic Analyses of Plasma Reveals New Insights into Asphyxia and Resuscitation in Pigs
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal, Klaus Weinberger Method for In Vitro Diagnosing a Complex Disease
Hans-Peter Deigner, Matthias Kohl, David P. Enot, Therese Koal, Matthias Keller Method for Predicting the Likelihood of an Onset of an Inflammation Associated Organ Failure
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal Method for normalization in metabolomics analysis methods with endogenous reference metabolites
Matthias Keller, Hans-Peter Deigner, David P. Enot, Matthias Kohl, Ronnaug Solberg, Ola D. Saugstad, Therese Koal Method of Diagnosing Asphyxia
Fabienne Flessa, Alexandra Kehl, Mohamed A. Imtiaz, Matthias Kohl Package RFLPtools: Tools to analyse RFLP data
Matthias Kohl, Hans-Peter Deigner Preprocessing of gene expression data by optimally robust estimators
Matthias Kohl, Peter Ruckdeschel R Package distrMod:S4 Classes and Methods for Probability Models
William J. Griffiths, Therese Koal, Yuqin Wang, Matthias Kohl, David P. Enot, Hans-Peter Deigner Targeted Metabolomics for Biomarker Discovery
Hans-Peter Deigner, David P. Enot, Matthias Kohl, Ignatius E. Igwe, Therese Koal, Michael Bauer, Guido Dallmann Use of Endogenous Metabolites for Early Diagnosing Sepsis

2009

Johannes Winning, Julia Reichel, Yvonne Eisenhut, Jürg Hamacher, Matthias Kohl, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Wolfgang Lösche Anti-platelet drugs and outcome in severe infection: Clinical impact and underlying mechanisms
Ralf A. Claus, Michael J. Dorer, Alexander C. Bunck, Hans-Peter Deigner Inhibition of Sphingomyelin Hydrolysis: Targeting the Lipid Mediator Ceramide as a Key Regulator of Cellular Fate
Salvatore Cuzzocrea, Hans-Peter Deigner, Tiziana Genovese, Emanuela Mazzon, Emanuela Esposito, Concetta Crisafulli, Rosanna Di Paola, Placido Bramanti, George Matuschak, Daniela Salvemini Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury
Petia Kovatcheva-Datchary, Markus Egert, Annet Maathuis, Mirjana Rajilic-Stojanovic, Albert A. de Graaf, Hauke Smidt, Willem M. de Vos, Koen Venema Linking phylogenetic identities of bacteria to starch fermentation in an in-vitro model of the large intestine by RNA-based stable isotope probing
Matthias Kohl Package ROptEstOld: Optimally robust estimation - old version
Matthias Kohl Package RobLoxBioC: Infinitesimally robust estimators for preprocessing omics data
Uwe Kern, Volker Busch, M. Rockland, Matthias Kohl, Frank Birklein Prävalenz und Risikofaktoren von Phantomschmerzen und Phantomwahrnehmungen in Deutschland
Hans-Peter Deigner, Matthias Kohl The molecular sepsis signature

2008

Susana Fuentes, Markus Egert, Maria Jimenez-Valera, Alberto Ramos-Cormenzana, Alfonso Ruiz-Bravo, Hauke Smidt, Mercedes Monteoliva-Sanchez Administration of Lactobacillus casei and Lactobacillus plantarum affects the diversity of murine intestinal lactobacilli, but not the overall bacterial community structure
Ralf Kinscherf, Hans-Peter Deigner Apoptogenic Signal Transduction in Arteriosclerosis-Associated Cells – Opportunities for Future Therapy?
Hans-Peter Deigner, Albin Hermetter Oxidized phospholipids: emerging lipid mediators in pathophysiology
Matthias Kohl Package MKmisc: Miscellaneous Functions from M. Kohl
Matthias Kohl, Peter Ruckdeschel, Myhailo Pupashenko, Gerald Kroisandt Package RobAStBase: Robust Asymptotic Statistics
Matthias Kohl, Peter Ruckdeschel Package distrMod: Object orientated implementation of probability models.
Eleonora Feist, Matthias Kohl, Peter Ruckdeschel, Anja Hueller distrTeach: Extensions of Package distr for Teaching Stochastics/Statistics in Secondary School

2007

Susana Fuentes, Markus Egert, Maria Jimenez-Valera, Mercedes Monteoliva-Sanchez, Alfonso Ruiz-Bravo, Hauke Smidt A strain of Lactobacillus plantarum affects segmented filamentous bacteria in the intestine of immunosuppressed mice
Matthias Kohl Bioconductor-Package SLqPCR: Functions for analysis of real-time quantitative PCR data at SIRS-Lab GmbH
Markus Egert, Albert A. de Graaf, Annet Maathuis, Pieter de Waard, Caroline M. Plugge, Hauke Smidt, Nicolaas E. Deutz, Cor Dijkema, Willem M. de Vos, Koen Venema Identification of glucose-fermenting bacteria present in an in vitro model of the human intestine by RNA-stable isotope probing
Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Dan Turcanu, Helmut Heinle, Wulf Dröge, Jürgen Metz, Ralf Kinscherf Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males
Matthias Kohl Package ROptEst: Optimally robust estimation
Matthias Kohl, Peter Ruckdeschel Package ROptRegTS: Optimally robust estimation for regressiontype models
Matthias Kohl Package RobRex: Optimally robust influence curves for regression and scale
Matthias Kohl Package SLmisc: Miscellaneous Functions for analysis of gene expression data at SIRS-Lab GmbH
Hans-Peter Deigner, E. Gulbins, Ralf A. Claus Sphingolipid Metabolism in Systemic Inflammation

2006

Markus Egert, Albert A. de Graaf, Hauke Smidt, Willem M. de Vos, Koen Venema Beyond diversity: Functional microbiomics of the human colon
Uwe Kern, Bernd Altkemper, Matthias Kohl Management of Phantom Pain with a Textile, Electromagnetically-Acting Stump Liner: A Randomized, Double-Blind, Crossover Study
Florian Setzer, Volker Oberle, Markus Bläss, Eva Möller, Stefan Rußwurm, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Konrad Reinhart, Wolfgang Lösche Platelet-derived microvesicles induce differential gene expression in monocytic cells: A DNA microarray study
Peter Ruckdeschel, Matthias Kohl, Thomas Stabla, Florian Camphausen S4Classes for Distributions
M. Harz, Ralf A. Claus, Clemens L. Bockmeyer, M. Baum, P. Rösch, Karim Kentouche, Hans-Peter Deigner, Jürgen Popp UV-Resonance Raman Spectroscopic Study of Human Plasma of Healthy Donors and Patients with Thrombotic Microangiopathy
Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla distrDoc: Documentation for packages distr, distrEx, distrSim, distrTEst, distrTeach, distrMod and distrEllipse

2005

Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Wulf Dröge, Jürgen Metz, Ralf Kinscherf Increased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects
Matthias Kohl Numerical Contributions to the Asymptotic Theory of Robustness
Matthias Kohl, Peter Ruckdeschel Package RandVar: Implementation of random variables by means of S4 classes and methods
Matthias Kohl, Peter Ruckdeschel Package distrEx: Extensions of package distr
Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla Package distrSim: Simulation classes based on package distr
Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla Package distrTEst: Estimation and testing classes based on package distr.
Markus Egert, Michael W. Friedrich Post-amplification Klenow fragment treatment alleviates PCR bias caused by partially single-stranded amplicons
Ralf A. Claus, Alexander C. Bunck, Clemens L. Bockmeyer, Frank M. Brunkhorst, Wolfgang Lösche, Ralf Kinscherf, Hans-Peter Deigner Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis
Markus Egert, Ulrich Stingl, Lars Dyhrberg Bruun, Bianca Pommerenke, Andreas Brune, Michael W. Friedrich Structure and Topology of Microbial Communities in the Major Gut Compartments of Melolontha melolontha Larvae (Coleoptera: Scarabaeidae)
Ralf A. Claus, Annette Wüstholz, Stefan Müller, Clemens L. Bockmeyer, Norman H. Riedel, Ralf Kinscherf, Hans-Peter Deigner Synthesis and Antiapoptotic Activity of a Novel Analogue of the Neutral Sphingomyelinase Inhibitor Scyphostatin
Thomas Hilberg, Hans-Peter Deigner, Eva Möller, Ralf A. Claus, Andriy Ruryk, Doreen Gläser, Julien Landre, Frank M. Brunkhorst, Konrad Reinhart, Holger H. Gabriel, Stefan Rußwurm Transcription in response to physical stress - clues to the molecular mechanisms of exercise-induced asthma
Ralf A. Claus, Clemens L. Bockmeyer, Karim Kentouche, Matthias W. Sieber, Volker Oberle, Roland Kaufmann, Hans-Peter Deigner, Wolfgang Lösche Transcriptional regulation of ADAMTS13
V. Tomic, Stefan Rußwurm, Eva Möller, Ralf A. Claus, Markus Bläss, Frank M. Brunkhorst, M. Brügel, K. Bode, F. Bloos, J. Wippermann, T. Wahlers, Hans-Peter Deigner, J. Thiery, Konrad Reinhart, Michael Bauer Transcriptomic and Proteomic Patterns of Systemic Inflammation in On-Pump and Off-Pump Coronary Artery Bypass Grafting

2004

Miroslav Prucha, Andriy Ruryk, Hinnerk Boriss, Eva Möller, Roman Zazula, Ivan Herold, Ralf A. Claus, Konrad Reinhart, Hans-Peter Deigner, Stefan Rußwurm Expression profiling: toward an application in sepsis diagnostics
Markus Egert, Sven Marhan, Bianca Wagner, Stefan Scheu, Michael W. Friedrich Molecular profiling of 16S rRNA genes reveals diet-related differences of microbial communities in soil, gut, and casts of Lumbricus terrestris L. (Oligochaeta: Lumbricidae)
Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla Package distr: Object orientated implementation of distributions
Alexandra Loidl, Ralf A. Claus, Elisabeth Ingolic, Hans-Peter Deigner, Albin Hermetter Role of ceramide in activation of stress-associated MAP kinases by minimally modified LDL in vascular smooth muscle cells

2003

Ralf Kinscherf, Konstantinos Cafaltzis, Falk Röder, Wulf Hildebrandt, Lutz Edler, Hans-Peter Deigner, Raoul Breitkreutz, Giso Feussner, Jörg Kreuzer, Egon Werle, Gerd Michel, Jürgen Metz, Wulf Dröge Cholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox status in hyperlipidemic subjects
Markus Egert, Michael W. Friedrich Formation of Pseudo-Terminal Restriction Fragments, a PCR-Related Bias Affecting Terminal Restriction Fragment Length Polymorphism Analysis of Microbial Community Structure
Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Jürgen Metz Hypercholesterolemia-Induced Long-Term Increase of Macrophages in the Myocardium of New Zealand White Rabbits
Markus Egert, Manfred Tevini Influence of Ultraviolet-B Radiation on Peroxidase Activity of Allium schoenoprasum Leaves
Stefan Rußwurm, Hans-Peter Deigner, Konrad Reinhart Microarray technology in sepsis: tool or toy?
Markus Egert, Bianca Wagner, Thorsten Lemke, Andreas Brune, Michael W. Friedrich Microbial Community Structure in Midgut and Hindgut of the Humus-Feeding Larva of Pachnoda ephippiata (Coleoptera: Scarabaeidae)
Alexandra Loidl, Eva Sevcsik, Gernot Riesenhuber, Hans-Peter Deigner, Albin Hermetter Oxidized Phospholipids in Minimally Modified Low Density Lipoprotein Induce Apoptotic Signaling via Activation of Acid Sphingomyelinase in Arterial Smooth Muscle Cells
Thorsten Lemke, Ulrich Stingl, Markus Egert, Michael W. Friedrich, Andreas Brune Physicochemical Conditions and Microbial Activities in the Highly Alkaline Gut of the Humus-Feeding Larva of Pachnoda ephippiata (Coleoptera: Scarabaeidae)

2002

Alexandra Loidl, Ralf A. Claus, Hans-Peter Deigner, Albin Hermetter High-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates
Markus Egert, Manfred Tevini Influence of drought on some physiological parameters symptomatic for oxidative stress in leaves of chives (Allium schoenoprasum)

2001

Hans-Peter Deigner, Ralf A. Claus, Gabriel A. Bonaterra, Christof Gehrke, Nilofar Bibak, Markus Bläss, Michael Cantz, Jürgen Metz, Ralf Kinscherf Ceramide induces aSMase expression: implications for oxLDL-induced apoptosis
Helmut Weicker, Ralf Kinscherf, Karin Diserens, Hans-Peter Deigner, Heiko Strüder Physiology and pathophysiology of basalganglia: impact on motor system function
Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Matthias Wiederhold, Andrea Luber, Peter F. Zipfel, Hans-Peter Deigner, Konrad Reinhart Procalcitonin and CGRP-I mRNA expression in various human tissues
Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Peter F. Zipfel, Hans-Peter Deigner, Konrad Reinhart Various human tissues express procalcitonin and CGRP-I mRNA

2000

Ralf A. Claus, Ralf Kinscherf, Christof Gehrke, Gabriel A. Bonaterra, Purusotam Basnet, Jürgen Metz, Hans-Peter Deigner Antiapoptotic Effects of Propolis Extract and Propol on Human Macrophages Exposed to Minimally Modified Low Density Lipoprotein
Hans-Peter Deigner, Uwe Haberkorn, Ralf Kinscherf Apoptosis modulators in the therapy of neurodegenerative diseases
Ralf A. Claus, Stefan Rußwurm, M. Meisner, Ralf Kinscherf, Hans-Peter Deigner Modulation of the ceramide level, a novel therapeutic concept?

1999

Ralf Kinscherf, Martin Wagner, Huse Kamencic, Gabriel A. Bonaterra, Dongming Hou, Rainer A. Schiele, Hans-Peter Deigner, Jürgen Metz Characterization of apoptotic macrophages in atheromatous tissue of humans and heritable hyperlipidemic rabbits
Ilmars Stonans, Elita Stonane, Stefan Rußwurm, Hans-Peter Deigner, Konrad J. Böhm, Matthias Wiederhold, Lothar Jäger, Konrad Reinhart HepG2 Human Hepatoma Cells Express Multiple Cytokine Genes
Hans-Peter Deigner, Ralf Kinscherf Modulating apoptosis: current applications and prospects for future drug development
Hans-Peter Deigner, Ralf Kinscherf, Ralf A. Claus, Beatrix Fyrnys, Christopher Blencowe, Albin Hermetter Novel reversible, irreversible and fluorescent inhibitors of platelet-activating factor acetylhydrolase as mechanistic probes

1998

Walther Schmiedt, Ralf Kinscherf, Hans-Peter Deigner, Huse Kamencic, Olaf Nauen, Juliane Kilo, Hellmut Oelert, Jürgen Metz, Sucharit Bhakdi Complement C6 Deficiency Protects Against Diet-Induced Atherosclerosis in Rabbits

1997

Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Jürgen Metz Der Einfluß von Veränderungen des Blut-Cholesterinspiegels auf Makrophagen im Myokard von Kaninchen
Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Michael Schrader, Jürgen Metz Effect of alterations of blood cholesterol levels on macrophages in the myocardium of New Zealand White rabbits
Ralf Kinscherf, Hans-Peter Deigner, Claus Usinger, Johannes Pill, Martin Wagner, Huse Kamencic, Dongming Hou, Min Chen, Walther Schmiedt, Michael Schrader, Gyula Kovacs, Kanefusa Kato, Jürgen Metz Induction of mitochondrial manganese superoxide dismutase in macrophages by oxidized LDL: its relevance in atherosclerosis of humans and heritable hyperlipidemic rabbits
Ralf Kinscherf, Walther Schmiedt, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, S. Bhakdi, Jürgen Metz Komplement C6-Defizienz führt zu einem signifikant geringeren Anstieg von Makrophagen (CR3/43) und arteriosklerotischen Plaques in Cholesterin-gefütterten Kaninchen
Ralf Kinscherf, Ralf A. Claus, Hans-Peter Deigner, Olaf Nauen, Christoph Gehrke, Albin Hermetter, Stefan Rußwurm, Volker Daniel, Volker Hack, Jürgen Metz Modified low density lipoprotein delivers substrate for ceramide formation and stimulates the sphingomyelin-ceramide pathway in human macrophages
Hans-Peter Deigner, Ralf A. Claus, Ralf Kinscherf Modifiziertes LDL als Substratquelle für die Bildung von Ceramid
Beatrix Fyrnys, Ralf A. Claus, Gert Wolf, Hans-Peter Deigner Oxidized Low Density Lipoprotein Stimulates Protein Kinase C (PKC) Activity and Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Cells

1996

Ralf A. Claus, Beatrix Fyrnys, Hans-Peter Deigner, Gert Wolf Oxidized Low-Density Lipoprotein Stimulates Protein Kinase C (PKC) and Induces Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Macrophage-Like Cells
M. A. Pajares, L. Alvarez, B. Gil Perez, M. L. Martinez Chantar, J. Mingorance, E. Sanchez Gongora, Hans-Peter Deigner, M. Avila, J. M. Mato Regulation and structure of rat liver S-adenosylmethionine synthethase, a target enzyme for studies in liver injury
Hans-Peter Deigner, Ralf A. Claus Stimulation of mitogen activated protein kinase by LDL and oxLDL in human U-937 macrophage-like cells
Hans-Peter Deigner, Ralf A. Claus ox LDL induzierte Tyrosinkinase-Aktivität

1995

Hans-Peter Deigner, Christian E. Freyberg, S. Laufer Distribution and excretion of [14C]-labelled [2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5- yl]- [2'-14C]-acetic acid in rats
Christopher Blencowe, Albin Hermetter, Gert M. Kostner, Hans-Peter Deigner Enhanced Association of Platelet-activating Factor Acetylhydrolase with Lipoprotein (a) in Comparison with Low Density Lipoprotein
Hans-Peter Deigner, Christopher Blencowe, Christian E. Freyberg Prevalence of steric restrictions in enzymatic nitrile-hydrolysis of a preparation from Rhodococcus sp. 409
Hans-Peter Deigner, Jose M. Mato, Maria A. Pajares Study of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP
Beatrix Fyrnys, Christopher Blencowe, Hans-Peter Deigner Susceptibility of phospholipids of oxidizing LDL to enzymatic hydrolysis modulates uptake by P388D1 macrophage-like cells

1994

Hans-Peter Deigner, G. Wolf, U. Ohlenmacher, J. Reichling 1'-Hydroxyeugenol- and coniferyl alcohol derivatives as effective inhibitors of 5-lipoxygenase and Cu(2+)-mediated low density lipoprotein oxidation. Evidence for a dual mechanism
Hans-Peter Deigner, G. Wolf Oxidativ modifiziertes LDL und seine mögliche Rolle in der Atherogenese

1993

Hans-Peter Deigner, Christian E. Freyberg, R. Heck Chemoenzymatic synthesis of carbon-14 labelled antioxidants
Hans-Peter Deigner, Hans A. Dresel Effect of platelet activating factor on the kinetics of LDL oxidation in vitro
Hans-Peter Deigner, Beatrix Fyrnys Synthesis of [32P]labelled 1-O-alkyl-2-desoxy-2-amino-sn′-glycero-3-phosphocholines

1992

Hans-Peter Deigner, Beatrix Fyrnys Rapid synthesis of 2-desoxy-2-amino-3-phosphocholine-glycerinic-acid-alkylester, 1-alkyl-1-desoxy- and 1-O-alkyl-2-desoxy-2-amino-sn-glycero-3-phosphocholines, -3-phospho-N,N′-dimethylethanolamine and -3-phospho-Fmoc-serine-methylester
Hans-Peter Deigner, E. Friedrich, H. Sinn, Hans A. Dresel Scavenging of lipid peroxidation products from oxidizing LDL by albumin alters the plasma half-life of a fraction of oxidized LDL particles

1991

Hans-Peter Deigner Über eine mögliche Rolle von Proteinen bei der LDL-Oxidation

1990

Richard Neidlein, Take Constantinescu, Claus Krieger, Hans-Peter Deigner A Convenient Solid-Support Procedure for the Synthesis of Symmetric Disulphides. The Configuration of Aromatic Carben Atoms in the 1,6-Methano[10]annulene Framework
Hans A. Dresel, Hans-Peter Deigner, J. Frübis, K. Strein, G. Schettler LDL-metabolism of the arterial wall-new implications for atherogenesis

1989

Hans-Peter Deigner, Wing C. Law, Francisco J. Canada, Robert R. Rando Membranes as the energy source in the endergonic transformation of vitamin A to 11-cis-retinols

1988

Richard Neidlein, Hans-Peter Deigner Biotransformation of 4-Oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[5.2.1.0 2,6endo]dec-8-en-3on an der Ratte
Richard Neidlein, Hans-Peter Deigner, W. Kramer In vivo- und in vitro-Untersuchung von synthetischem Vergleichsmaterial zu Stoffwechselprodukten von 4-0xa-5-exo-(N-methylcarbamoyloxy-tricyclo[5.2.1.0.2,6endo]dec-8-en-3d-oenr Ratte
Richard Neidlein, Hans-Peter Deigner Pharmakokinetik von 4-oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[5:2.1.0. 2,6-endo]dec-8-en-3on an der Ratte