Publikationen

Institute of Precision Medicine

2018 | 2017 | 2016 | 2015 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988

2018

Steve Przybilla Erotisch, aber nicht hygienisch: Interview des Tages; Markus Egert - der Keimjäger
Elena Herrmann, Wayne Young, Verena Reichert-Grimm, Severin Weis, Christian U. Riedel, Douglas Rosendale, Halina Stoklosinski, Martin Hunt, Markus Egert In Vivo Assessment of Resistant Starch Degradation by the Caecal Microbiota of Mice Using RNA-Based Stable Isotope Probing — A Proof-of-Principle Study
Hans-Peter Deigner (Hrsg.), Matthias Kohl (Hrsg.) Precision Medicine: Tools and Quantitative Approaches
Stephan Vilgis, Hans-Peter Deigner Sequencing in Precision Medicine
Lars Kaiser, Julia Weisser, Matthias Kohl, Hans-Peter Deigner Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection
Simon Schomäcker Weihwasser: Heilig aber nicht keimfrei
Wo lauern die größten Keimfallen im Haushalt, Herr Professor? Mikrobiologe Prof. Dr. Markus Egert verrät, worauf es im Kampf gegen Bakterien und Co. wirklich ankommt

2017

Lars Saemann, Karin Lachner, Folker Wenzel Cardiac frequency and cutaneous microcirculation during and after exercising in the view of physical condition
Hans-Peter Deigner, Matthias Kohl, Christoph Ruppert, Sowmya S. Perumbakkam, Lisa Jacob, Anika Schmidt Diagnostische Schnelltests für die personalisierte Medizin
Severin Weis, Elena Herrmann, Christian U. Riedel, Wayne Young, Sylvia Schnell, Markus Egert Effect of rotor type and formamide concentration on the separation of isotope-labeled and unlabeled Escherichia coli RNA by isopycnic density ultracentrifugation
Elena Herrmann, Wayne Young, Christian Riedel, Markus Egert Funktionelle Mikrobiomik am Beispiel der Verdauung präbiotischer Kohlenhydrate
Markus Egert Gischt aus der Kloschüssel
Markus Egert Leben auf dem Menschen - Struktur und Funktion der humanen Haut-Mikrobiota
Markus Bläss, Nelly Bibak, Ralf A. Claus, Matthias Kohl, Gabriel A. Bonaterra, Ralf Kinscherf, Stefan Laufer, Hans-Peter Deigner NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation
Severin Weis, Stefan Ratering, Andreas Schwiertz, Marcus Unger, Karl-Herbert Schäfer, Sylvia Schnell, Markus Egert Next generation 16S ribosomal RNA gene sequencing revels intestinal bacterial genera with a potential role in Parkinson’s disease
R. Lohmüller, A.-S. Gangloff, Folker Wenzel, W. A. Lagreze Optikushypoplasie und septooptische Dysplasie
Markus Egert RNA-based stable isotope probing to link structure and function of prebiotics-assimilating microbiotas
Wolfgang Kemmler, Anja Weissenfels, Marc Teschler, Sebastian Willert, Michael Bebenek, Mahdieh Shojaa, Matthias Kohl, Ellen Freiberger, Cornel Sieber, Simon von Stengel Whole-body electromyostimulation and protein supplementation favorably affect sarcopenic obesity in community-dwelling older men at risk: the randomized controlled FranSO study

2016

Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Kanan M. Wahedy, Ihab M. Almasri, Rami Y. Morjan, Hans-Peter Deigner 1-(Pyridin-4-yl)-3-(2,4,6-trichlorophenyl)benz- [4,5]imidazo[1,2-d ][1,2,4]triazin-4(3H)-one
Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Hans-Peter Deigner 3-(2,4-Difluorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one
Ha-Yeun Chung, Daniel C. Hupe, Gordon P. Otto, Marcel Sprenger, Alexander C. Bunck, Michael J. Dorer, Clemens L. Bockmeyer, Hans-Peter Deigner, Markus H. Gräler, Ralf A. Claus Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis
Anja Bramhoff, Günther Giers, Frithjof Blessing, Folker Wenzel Using the mean platelet volume MPV for the quality assessment of apheresis procedures

2015

Wolfgang Kemmler, Michael Bebenek, Matthias Kohl, Simon von Stengel Körperliches Training, Fraktur und Knochendichte: Finale Ergebnisse der Erlanger Fitness und Osteoporose-Präventions-Studie (EFOPS)

2013

Nayla Jbeily, Iris Suckert, Falk A. Gonnert, Benedikt Acht, Clemens L. Bockmeyer, Sascha D. Grossmann, Markus Bläss, Anja Lüth, Hans-Peter Deigner, Michael Bauer, Ralf A. Claus Hyperresponsiveness of mice defi cient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response

2012

Ute Stemmer, Zsuzsanna A. Dunai, Daniel Koller, Gabriel Pürstinger, Elfriede Zenzmaier, Hans-Peter Deigner, Elma Aflaki, Dagmar Kratky, Albin Hermetter Toxicity of oxidized phospholipids in cultured macrophages

2011

Matthias Keller, David P. Enot, Mark P. Hodson, Emeka I. Igwe, Hans-Peter Deigner, Justin Dean, Hayde Bolouri, Hendrik Hagberg, Carina Mallard Inflammatory-Induced Hibernation in the Fetus: Priming of Fetal Sheep Metabolism Correlates with Developmental Brain Injury
Nigel Francis, See Heng Wong, Peter Hampson, Keqing Wang, Stephen P. Young, Hans-Peter Deigner, Michael Salmon, Dagmar Scheel-Toellner, Janet M. Lord Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events
Hans-Peter Deigner, Michael Bauer, Matthias Kohl Method for in vitro diagnosing sepsis utilizing biomarker composed of more than two different types of endogenous biomolecules
Hans-Peter Deigner, Matthias Kohl, Therese Koal, Ignatius E. Igwe, Guido Dallmann, Michael Bauer, David P. Enot Use of bile acids for prediction of an onset of sepsis

2010

Julien B. Landré, Markus Bläss, Matthias Kohl, Tina Schlicksbier, Andriy Ruryk, Ralf Kinscherf, Ralf A. Claus, Albin Hermetter, Matthias Keller, Michael Bauer, Hans-Peter Deigner Addressable bipartite molecular hook (ABMH): Immobilized hairpin probes with sensitivity below 50 fM
Ralf A. Claus, Gordon P. Otto, Hans-Peter Deigner, Michael Bauer Approaching Clinical Reality: Markers for Monitoring Systemic Inflammation and Sepsis
Michael Urban, David P. Enot, Guido Dallmann, Lisa Körner, Verena Forcher, Peter Enoh, Therese Koal, Matthias Keller, Hans-Peter Deigner Complexity and pitfalls of mass spectrometry-based targeted metabolomics in brain research
Ronnaug Solberg, David P. Enot, Hans-Peter Deigner, Therese Koal, Sabine Scholl-Bürgi, Ola D. Saugstad, Matthias Keller Metabolomic Analyses of Plasma Reveals New Insights into Asphyxia and Resuscitation in Pigs
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal, Klaus Weinberger Method for In Vitro Diagnosing a Complex Disease
Hans-Peter Deigner, Matthias Kohl, David P. Enot, Therese Koal, Matthias Keller Method for Predicting the Likelihood of an Onset of an Inflammation Associated Organ Failure
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal Method for normalization in metabolomics analysis methods with endogenous reference metabolites
Matthias Keller, Hans-Peter Deigner, David P. Enot, Matthias Kohl, Ronnaug Solberg, Ola D. Saugstad, Therese Koal Method of Diagnosing Asphyxia
Matthias Kohl, Hans-Peter Deigner Preprocessing of gene expression data by optimally robust estimators

2009

Johannes Winning, Julia Reichel, Yvonne Eisenhut, Jürg Hamacher, Matthias Kohl, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Wolfgang Lösche Anti-platelet drugs and outcome in severe infection: Clinical impact and underlying mechanisms
Ralf A. Claus, Michael J. Dorer, Alexander C. Bunck, Hans-Peter Deigner Inhibition of Sphingomyelin Hydrolysis: Targeting the Lipid Mediator Ceramide as a Key Regulator of Cellular Fate
Salvatore Cuzzocrea, Hans-Peter Deigner, Tiziana Genovese, Emanuela Mazzon, Emanuela Esposito, Concetta Crisafulli, Rosanna Di Paola, Placido Bramanti, George Matuschak, Daniela Salvemini Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury

2008

Hans-Peter Deigner, Albin Hermetter Oxidized phospholipids: emerging lipid mediators in pathophysiology
Eleonora Feist, Matthias Kohl, Peter Ruckdeschel, Anja Hueller distrTeach: Extensions of Package distr for Teaching Stochastics/Statistics in Secondary School

2007

Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Dan Turcanu, Helmut Heinle, Wulf Dröge, Jürgen Metz, Ralf Kinscherf Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males

2006

Florian Setzer, Volker Oberle, Markus Bläss, Eva Möller, Stefan Rußwurm, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Konrad Reinhart, Wolfgang Lösche Platelet-derived microvesicles induce differential gene expression in monocytic cells: A DNA microarray study
M. Harz, Ralf A. Claus, Clemens L. Bockmeyer, M. Baum, P. Rösch, Karim Kentouche, Hans-Peter Deigner, Jürgen Popp UV-Resonance Raman Spectroscopic Study of Human Plasma of Healthy Donors and Patients with Thrombotic Microangiopathy

2005

Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Wulf Dröge, Jürgen Metz, Ralf Kinscherf Increased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects
Ralf A. Claus, Alexander C. Bunck, Clemens L. Bockmeyer, Frank M. Brunkhorst, Wolfgang Lösche, Ralf Kinscherf, Hans-Peter Deigner Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis
Ralf A. Claus, Annette Wüstholz, Stefan Müller, Clemens L. Bockmeyer, Norman H. Riedel, Ralf Kinscherf, Hans-Peter Deigner Synthesis and Antiapoptotic Activity of a Novel Analogue of the Neutral Sphingomyelinase Inhibitor Scyphostatin
Thomas Hilberg, Hans-Peter Deigner, Eva Möller, Ralf A. Claus, Andriy Ruryk, Doreen Gläser, Julien Landre, Frank M. Brunkhorst, Konrad Reinhart, Holger H. Gabriel, Stefan Rußwurm Transcription in response to physical stress - clues to the molecular mechanisms of exercise-induced asthma
Ralf A. Claus, Clemens L. Bockmeyer, Karim Kentouche, Matthias W. Sieber, Volker Oberle, Roland Kaufmann, Hans-Peter Deigner, Wolfgang Lösche Transcriptional regulation of ADAMTS13
V. Tomic, Stefan Rußwurm, Eva Möller, Ralf A. Claus, Markus Bläss, Frank M. Brunkhorst, M. Brügel, K. Bode, F. Bloos, J. Wippermann, T. Wahlers, Hans-Peter Deigner, J. Thiery, Konrad Reinhart, Michael Bauer Transcriptomic and Proteomic Patterns of Systemic Inflammation in On-Pump and Off-Pump Coronary Artery Bypass Grafting

2004

Miroslav Prucha, Andriy Ruryk, Hinnerk Boriss, Eva Möller, Roman Zazula, Ivan Herold, Ralf A. Claus, Konrad Reinhart, Hans-Peter Deigner, Stefan Rußwurm Expression profiling: toward an application in sepsis diagnostics
Alexandra Loidl, Ralf A. Claus, Elisabeth Ingolic, Hans-Peter Deigner, Albin Hermetter Role of ceramide in activation of stress-associated MAP kinases by minimally modified LDL in vascular smooth muscle cells

2003

Ralf Kinscherf, Konstantinos Cafaltzis, Falk Röder, Wulf Hildebrandt, Lutz Edler, Hans-Peter Deigner, Raoul Breitkreutz, Giso Feussner, Jörg Kreuzer, Egon Werle, Gerd Michel, Jürgen Metz, Wulf Dröge Cholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox status in hyperlipidemic subjects
Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Jürgen Metz Hypercholesterolemia-Induced Long-Term Increase of Macrophages in the Myocardium of New Zealand White Rabbits
Stefan Rußwurm, Hans-Peter Deigner, Konrad Reinhart Microarray technology in sepsis: tool or toy?
Alexandra Loidl, Eva Sevcsik, Gernot Riesenhuber, Hans-Peter Deigner, Albin Hermetter Oxidized Phospholipids in Minimally Modified Low Density Lipoprotein Induce Apoptotic Signaling via Activation of Acid Sphingomyelinase in Arterial Smooth Muscle Cells

2002

Alexandra Loidl, Ralf A. Claus, Hans-Peter Deigner, Albin Hermetter High-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates

2001

Hans-Peter Deigner, Ralf A. Claus, Gabriel A. Bonaterra, Christof Gehrke, Nilofar Bibak, Markus Bläss, Michael Cantz, Jürgen Metz, Ralf Kinscherf Ceramide induces aSMase expression: implications for oxLDL-induced apoptosis
Helmut Weicker, Ralf Kinscherf, Karin Diserens, Hans-Peter Deigner, Heiko Strüder Physiology and pathophysiology of basalganglia: impact on motor system function
Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Matthias Wiederhold, Andrea Luber, Peter F. Zipfel, Hans-Peter Deigner, Konrad Reinhart Procalcitonin and CGRP-I mRNA expression in various human tissues
Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Peter F. Zipfel, Hans-Peter Deigner, Konrad Reinhart Various human tissues express procalcitonin and CGRP-I mRNA

2000

Ralf A. Claus, Ralf Kinscherf, Christof Gehrke, Gabriel A. Bonaterra, Purusotam Basnet, Jürgen Metz, Hans-Peter Deigner Antiapoptotic Effects of Propolis Extract and Propol on Human Macrophages Exposed to Minimally Modified Low Density Lipoprotein
Hans-Peter Deigner, Uwe Haberkorn, Ralf Kinscherf Apoptosis modulators in the therapy of neurodegenerative diseases
Ralf A. Claus, Stefan Rußwurm, M. Meisner, Ralf Kinscherf, Hans-Peter Deigner Modulation of the ceramide level, a novel therapeutic concept?

1999

Ralf Kinscherf, Martin Wagner, Huse Kamencic, Gabriel A. Bonaterra, Dongming Hou, Rainer A. Schiele, Hans-Peter Deigner, Jürgen Metz Characterization of apoptotic macrophages in atheromatous tissue of humans and heritable hyperlipidemic rabbits
Ilmars Stonans, Elita Stonane, Stefan Rußwurm, Hans-Peter Deigner, Konrad J. Böhm, Matthias Wiederhold, Lothar Jäger, Konrad Reinhart HepG2 Human Hepatoma Cells Express Multiple Cytokine Genes
Hans-Peter Deigner, Ralf Kinscherf Modulating apoptosis: current applications and prospects for future drug development
Hans-Peter Deigner, Ralf Kinscherf, Ralf A. Claus, Beatrix Fyrnys, Christopher Blencowe, Albin Hermetter Novel reversible, irreversible and fluorescent inhibitors of platelet-activating factor acetylhydrolase as mechanistic probes

1998

Walther Schmiedt, Ralf Kinscherf, Hans-Peter Deigner, Huse Kamencic, Olaf Nauen, Juliane Kilo, Hellmut Oelert, Jürgen Metz, Sucharit Bhakdi Complement C6 Deficiency Protects Against Diet-Induced Atherosclerosis in Rabbits

1997

Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Jürgen Metz Der Einfluß von Veränderungen des Blut-Cholesterinspiegels auf Makrophagen im Myokard von Kaninchen
Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Michael Schrader, Jürgen Metz Effect of alterations of blood cholesterol levels on macrophages in the myocardium of New Zealand White rabbits
Ralf Kinscherf, Hans-Peter Deigner, Claus Usinger, Johannes Pill, Martin Wagner, Huse Kamencic, Dongming Hou, Min Chen, Walther Schmiedt, Michael Schrader, Gyula Kovacs, Kanefusa Kato, Jürgen Metz Induction of mitochondrial manganese superoxide dismutase in macrophages by oxidized LDL: its relevance in atherosclerosis of humans and heritable hyperlipidemic rabbits
Ralf Kinscherf, Walther Schmiedt, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, S. Bhakdi, Jürgen Metz Komplement C6-Defizienz führt zu einem signifikant geringeren Anstieg von Makrophagen (CR3/43) und arteriosklerotischen Plaques in Cholesterin-gefütterten Kaninchen
Ralf Kinscherf, Ralf A. Claus, Hans-Peter Deigner, Olaf Nauen, Christoph Gehrke, Albin Hermetter, Stefan Rußwurm, Volker Daniel, Volker Hack, Jürgen Metz Modified low density lipoprotein delivers substrate for ceramide formation and stimulates the sphingomyelin-ceramide pathway in human macrophages
Hans-Peter Deigner, Ralf A. Claus, Ralf Kinscherf Modifiziertes LDL als Substratquelle für die Bildung von Ceramid
Beatrix Fyrnys, Ralf A. Claus, Gert Wolf, Hans-Peter Deigner Oxidized Low Density Lipoprotein Stimulates Protein Kinase C (PKC) Activity and Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Cells

1996

Ralf A. Claus, Beatrix Fyrnys, Hans-Peter Deigner, Gert Wolf Oxidized Low-Density Lipoprotein Stimulates Protein Kinase C (PKC) and Induces Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Macrophage-Like Cells
M. A. Pajares, L. Alvarez, B. Gil Perez, M. L. Martinez Chantar, J. Mingorance, E. Sanchez Gongora, Hans-Peter Deigner, M. Avila, J. M. Mato Regulation and structure of rat liver S-adenosylmethionine synthethase, a target enzyme for studies in liver injury
Hans-Peter Deigner, Ralf A. Claus Stimulation of mitogen activated protein kinase by LDL and oxLDL in human U-937 macrophage-like cells
Hans-Peter Deigner, Ralf A. Claus ox LDL induzierte Tyrosinkinase-Aktivität

1995

Hans-Peter Deigner, Christian E. Freyberg, S. Laufer Distribution and excretion of [14C]-labelled [2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5- yl]- [2'-14C]-acetic acid in rats
Christopher Blencowe, Albin Hermetter, Gert M. Kostner, Hans-Peter Deigner Enhanced Association of Platelet-activating Factor Acetylhydrolase with Lipoprotein (a) in Comparison with Low Density Lipoprotein
Hans-Peter Deigner, Christopher Blencowe, Christian E. Freyberg Prevalence of steric restrictions in enzymatic nitrile-hydrolysis of a preparation from Rhodococcus sp. 409
Hans-Peter Deigner, Jose M. Mato, Maria A. Pajares Study of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP
Beatrix Fyrnys, Christopher Blencowe, Hans-Peter Deigner Susceptibility of phospholipids of oxidizing LDL to enzymatic hydrolysis modulates uptake by P388D1 macrophage-like cells

1994

Hans-Peter Deigner, G. Wolf, U. Ohlenmacher, J. Reichling 1'-Hydroxyeugenol- and coniferyl alcohol derivatives as effective inhibitors of 5-lipoxygenase and Cu(2+)-mediated low density lipoprotein oxidation. Evidence for a dual mechanism
Hans-Peter Deigner, G. Wolf Oxidativ modifiziertes LDL und seine mögliche Rolle in der Atherogenese

1993

Hans-Peter Deigner, Christian E. Freyberg, R. Heck Chemoenzymatic synthesis of carbon-14 labelled antioxidants
Hans-Peter Deigner, Hans A. Dresel Effect of platelet activating factor on the kinetics of LDL oxidation in vitro
Hans-Peter Deigner, Beatrix Fyrnys Synthesis of [32P]labelled 1-O-alkyl-2-desoxy-2-amino-sn′-glycero-3-phosphocholines

1992

Hans-Peter Deigner, Beatrix Fyrnys Rapid synthesis of 2-desoxy-2-amino-3-phosphocholine-glycerinic-acid-alkylester, 1-alkyl-1-desoxy- and 1-O-alkyl-2-desoxy-2-amino-sn-glycero-3-phosphocholines, -3-phospho-N,N′-dimethylethanolamine and -3-phospho-Fmoc-serine-methylester
Hans-Peter Deigner, E. Friedrich, H. Sinn, Hans A. Dresel Scavenging of lipid peroxidation products from oxidizing LDL by albumin alters the plasma half-life of a fraction of oxidized LDL particles

1991

Hans-Peter Deigner Über eine mögliche Rolle von Proteinen bei der LDL-Oxidation

1990

Richard Neidlein, Take Constantinescu, Claus Krieger, Hans-Peter Deigner A Convenient Solid-Support Procedure for the Synthesis of Symmetric Disulphides. The Configuration of Aromatic Carben Atoms in the 1,6-Methano[10]annulene Framework

1989

Hans-Peter Deigner, Wing C. Law, Francisco J. Canada, Robert R. Rando Membranes as the energy source in the endergonic transformation of vitamin A to 11-cis-retinols

1988

Richard Neidlein, Hans-Peter Deigner Biotransformation of 4-Oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[5.2.1.0 2,6endo]dec-8-en-3on an der Ratte
Richard Neidlein, Hans-Peter Deigner, W. Kramer In vivo- und in vitro-Untersuchung von synthetischem Vergleichsmaterial zu Stoffwechselprodukten von 4-0xa-5-exo-(N-methylcarbamoyloxy-tricyclo[5.2.1.0.2,6endo]dec-8-en-3d-oenr Ratte
Richard Neidlein, Hans-Peter Deigner Pharmakokinetik von 4-oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[5:2.1.0. 2,6-endo]dec-8-en-3on an der Ratte