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Prof. Dr. rer. nat. habil. Hans-Peter Deigner

Hans-Peter Deigner
  • Fakultät Medical and Life Sciences
  • Villingen-Schwenningen Campus
  • Room B 2.06
  • Phone 07720 307-4232

Office hours

Sprechzeiten: nach Vereinbarung

Field of research and / or teaching


  • Biomarker 
  • Molekulare Diagnostik 
  • Metabolomics 
  • Biobanking 
  • Spezielle Aspekte der Systembiologie
  • Gastwissenschaftler Fraunhofer Gesellschaft, Institut für Zelltherapie und Immunologie (IZI), EXIM, Rostock
  • Gründungsmitglied und Mitglied des Exekutivkomitees der Europäischen Gesellschaft für Biopreservation und Biobanking (ESBB,


Deigner, Hans-Peter

2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988


Benjamin Brandes, Sophie Hoenke, Michael Türk, Björn Weber, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene CsukA unified strategy for the synthesis of amorfrutins A and B and evaluation of their cytotoxicity
Oliver Riester, Max Borgolte, Rene Csuk, Hans-Peter DeignerChallenges in Bone Tissue Regeneration: Stem Cell Therapy, Biofunctionality and Antimicrobial Properties of Novel Materials and Its Evolution
Mostafa Mahmoud, Christoph Ruppert, Simone Rentschler, Stefan Laufer, Hans-Peter DeignerCombining aptamers and antibodies: lateral flow quantification for thrombin and interleukin-6 with smartphone readout
Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Rene Csuk, Hans-Peter DeignerDrugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19
Simone Rentschler, Lars Kaiser, Hans-Peter DeignerEmerging Options for the Diagnosis of Bacterial Infections and the Characterization of Antimicrobial Resistance
Teresa Schätzl, Lars Kaiser, Hans-Peter DeignerFacioscapulohumeral muscular dystrophy: genetics, gene activation and downstream signalling with regard to recent therapeutic approaches: an update
Abid A. Khan, Khanzadi N. Manzoor, Aamir Sultan, Maria Saeed, Mahrukh Rafique, Sameen Noushad, Ayesha Talib, Simone Rentschler, Hans-Peter DeignerPulling the Brakes on Fast and Furious Multiple Drug-Resistant (MDR) Bacteria
Nico Laur, Lars Kaiser, Hans-Peter Deigner, Ralf KinscherfSequential Analysis of Trace Elements in a Micro Volume Urine Sample Using Inductively Coupled Plasma Mass Spectrometry


Sophie Hoenke, Niels V. Heise, Michael Kahnt, Hans-Peter Deigner, Rene CsukBetulinic acid derived amides are highly cytotoxic, apoptotic and selective
Markus Blaess, Lars Kaiser, Martin Sauer, Rene Csuk, Hans-Peter DeignerCOVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks
Christoph Ruppert, Lars Kaiser, Lisa Jacob, Stefan Laufer, Matthias Kohl, Hans-Peter DeignerDuplex Shiny app quantification of the sepsis biomarkers C-reactive protein and interleukin-6 in a fast quantum dot labeled lateral flow assay
Nico Laur, Ralf Kinscherf, Karolina Pomytkin, Lars Kaiser, Otto Knes, Hans-Peter DeignerICP-MS trace element analysis in serum and whole blood
Markus Bläss, Lars Kaiser, Martin Sauer, Hans-Peter DeignerLysosomotropic Active Compounds — Hidden Protection against COVID-19 / SARS-CoV-2 Infection?
Lars Kaiser, Helga Weinschrott, Isabel Quint, Markus Blaess, Rene Csuk, Manfred Jung, Matthias Kohl, Hans-Peter DeignerMetabolite Patterns in Human Myeloid Hematopoiesis Result from Lineage-Dependent Active Metabolic Pathways
Sophie Hoenke, Immo Serbian, Hans-Peter Deigner, Rene CuskMitocanic Di- and Triterpenoid Rhodamine B Conjugates
Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Simone Rentschler, Rene Csuk, Hans-Peter DeignerRational Drug Repurposing: Focus on Lysosomotropism, Targets in Disease Process, Drug Profile, and Pulmonary Tissue Accumulation in SARS-CoV-2 Infection/COVID-19
Benjamin Brandes, Lukas Koch, Sophie Hoenke, Hans-Peter Deigner, Rene CsukThe presence of a cationic center is not alone decisive for the cytotoxicity of triterpene carboxylic acid amides


Christoph Ruppert, Navneet Phogat, Stefan Laufer, Matthias Kohl, Hans-Peter DeignerA smartphone readout system for gold nanoparticle-based lateral flow assays: application to monitoring of digoxigenin
Mostafa Mahmoud, Stefan Laufer, Hans-Peter DeignerAn aptamer based thermofluorimetric assay for ethanolamine
Mostafa Mahmoud, Stefan Laufer, Hans-Peter DeignerData for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
Markus Blaess, Hans-Peter DeignerDerailed Ceramide Metabolism in Atopic Dermatitis (AD): A Causal Starting Point for a Personalized (Basic) Therapy
Markus Blaess, Hans-Peter DeignerFocusing on derailed cellular ceramide metabolism fosters recovery of atopic dermatitis lesions and psoriasis plaques
Markus Blaess, Folker Wenzel, Hans-Peter DeignerRecovery of derailed ceramide metabolism in atopic dermatitis: a successful topical off-label use of amitriptyline combined with linoleic acid
Rene Csuk, Hans-Peter DeignerThe potential of click reactions for the synthesis of bioactive triterpenes
Mostafa Mahmoud, Stefan Laufer, Hans-Peter DeignerVisual aptamer-based capillary assay for ethanolamine using magnetic particles and strand displacement


Hans-Peter Deigner(Ed.), , Matthias Kohl(Ed.)Precision Medicine: Tools and Quantitative Approaches
Stephan Vilgis, Hans-Peter DeignerSequencing in Precision Medicine
Lars Kaiser, Julia Weisser, Matthias Kohl, Hans-Peter DeignerSmall molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection


Kanan M. Wahedy, Bassam Abu Thaher, Dieter Schollmeyer, Ihab M. Almasri, Rami Y. Morjan, Basem Qeshta, Hans-Peter DeignerCrystal structures of pure 3-(4-bromo-2-chlorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one and contaminated with 3-(4-bromophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one
Hans-Peter Deigner, Matthias Kohl, Christoph Ruppert, Sowmya S. Perumbakkam, Lisa Jacob, Anika SchmidtDiagnostische Schnelltests für die personalisierte Medizin
Markus Bläss, Nelly Bibak, Ralf A. Claus, Matthias Kohl, Gabriel A. Bonaterra, Ralf Kinscherf, Stefan Laufer, Hans-Peter DeignerNB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation


Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Kanan M. Wahedy, Ihab M. Almasri, Rami Y. Morjan, Hans-Peter Deigner1-(Pyridin-4-yl)-3-(2,4,6-trichlorophenyl)benz- [4,5]imidazo[1,2-d ][1,2,4]triazin-4(3H)-one
Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Hans-Peter Deigner3-(2,4-Difluorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one
Ha-Yeun Chung, Daniel C. Hupe, Gordon P. Otto, Marcel Sprenger, Alexander C. Bunck, Michael J. Dorer, Clemens L. Bockmeyer, Hans-Peter Deigner, Markus H. Gräler, Ralf A. ClausAcid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis
Hans-Peter DeignerBimodal imaging and beyond: Editorial
Basri Gülbakan, Riza Köksal Özgül, Ayse Yüzbasioglu, Matthias Kohl, Hans-Peter Deigner, Meral ÖzgücDiscovery of biomarkers in rare diseases: innovative approaches by predictive and personalized medicine
Mario Brameshuber, Eva Sevcsik, Benedikt K. Rossboth, Christina Manner, Hans-Peter Deigner, Begüm Peksel, Mária Péter, Zsolt Török, Albin Hermetter, Gerhard J. SchützOxidized Phospholipids Inhibit the Formation of Cholesterol-Dependent Plasma Membrane Nanoplatforms


Mostafa Mahmoud, Hans-Peter DeignerAptamers in Diagnostics: Replacing or Complementing Antibodies?
Markus Bläss, Ralf A. Claus, Hans-Peter DeignerHPLC separation and ultrasensitive optical quantification of ceramide species applying 7-(diethylamino)coumarin-3-carbonyl azide derivatisation
Christoph Ruppert, Matthias Kohl, Lisa Jacob, Hans-Peter DeignerMultiplexing in Bioassays
Markus Bläss, H.P. Le, Ralf A. Claus, Matthias Kohl, Hans-Peter DeignerStereospecific Induction of Apoptosis in Tumor Cells via Endogenous C16-Ceramide and Distinct Transcripts


Nayla Jbeily, Iris Suckert, Falk A. Gonnert, Benedikt Acht, Clemens L. Bockmeyer, Sascha D. Grossmann, Markus Bläss, Anja Lüth, Hans-Peter Deigner, Michael Bauer, Ralf A. ClausHyperresponsiveness of mice defi cient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response


Martina Weber, Sandro Lambeck, Nadine Ding, Stefanie Henken, Matthias Kohl, Hans-Peter Deigner, David P. Enot, Ignatius E. Igwe, Lucien Frappart, Michael Kiehntopf, Ralf A. Claus, Thomas Kamradt, Debra Weih, Yoram Vodovotz, David E. Briles, Abiodun D. Ogunniyi, James C. Paton, Ulrich A. Maus, Michael BauerHepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia
Ute Stemmer, Zsuzsanna A. Dunai, Daniel Koller, Gabriel Pürstinger, Elfriede Zenzmaier, Hans-Peter Deigner, Elma Aflaki, Dagmar Kratky, Albin HermetterToxicity of oxidized phospholipids in cultured macrophages


Matthias Kohl, S. Koch, Matthias Keller, Hans-Peter DeignerBiochips: Bright Future in Clinical Dx?
Matthias Keller, David P. Enot, Mark P. Hodson, Emeka I. Igwe, Hans-Peter Deigner, Justin Dean, Hayde Bolouri, Hendrik Hagberg, Carina MallardInflammatory-Induced Hibernation in the Fetus: Priming of Fetal Sheep Metabolism Correlates with Developmental Brain Injury
Nigel Francis, See Heng Wong, Peter Hampson, Keqing Wang, Stephen P. Young, Hans-Peter Deigner, Michael Salmon, Dagmar Scheel-Toellner, Janet M. LordLactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events
Hans-Peter Deigner, Michael Bauer, Matthias KohlMethod for in vitro diagnosing sepsis utilizing biomarker composed of more than two different types of endogenous biomolecules
Hans-Peter Deigner, Matthias Kohl, Therese Koal, Ignatius E. Igwe, Guido Dallmann, Michael Bauer, David P. EnotUse of bile acids for prediction of an onset of sepsis


Julien B. Landré, Markus Bläss, Matthias Kohl, Tina Schlicksbier, Andriy Ruryk, Ralf Kinscherf, Ralf A. Claus, Albin Hermetter, Matthias Keller, Michael Bauer, Hans-Peter DeignerAddressable bipartite molecular hook (ABMH): Immobilized hairpin probes with sensitivity below 50 fM
Ralf A. Claus, Gordon P. Otto, Hans-Peter Deigner, Michael BauerApproaching Clinical Reality: Markers for Monitoring Systemic Inflammation and Sepsis
Therese Koal, Hans-Peter DeignerChallenges in Mass Spectrometry Based Targeted Metabolomics
Michael Urban, David P. Enot, Guido Dallmann, Lisa Körner, Verena Forcher, Peter Enoh, Therese Koal, Matthias Keller, Hans-Peter DeignerComplexity and pitfalls of mass spectrometry-based targeted metabolomics in brain research
Hans-Peter Deigner, Ancha BaranovaCurrent Methods and Perspectives in Biomarker Discovery: Editorial
Ronnaug Solberg, David P. Enot, Hans-Peter Deigner, Therese Koal, Sabine Scholl-Bürgi, Ola D. Saugstad, Matthias KellerMetabolomic Analyses of Plasma Reveals New Insights into Asphyxia and Resuscitation in Pigs
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal, Klaus WeinbergerMethod for In Vitro Diagnosing a Complex Disease
Hans-Peter Deigner, Matthias Kohl, David P. Enot, Therese Koal, Matthias KellerMethod for Predicting the Likelihood of an Onset of an Inflammation Associated Organ Failure
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese KoalMethod for normalization in metabolomics analysis methods with endogenous reference metabolites
Matthias Keller, Hans-Peter Deigner, David P. Enot, Matthias Kohl, Ronnaug Solberg, Ola D. Saugstad, Therese KoalMethod of Diagnosing Asphyxia
Matthias Kohl, Hans-Peter DeignerPreprocessing of gene expression data by optimally robust estimators
William J. Griffiths, Therese Koal, Yuqin Wang, Matthias Kohl, David P. Enot, Hans-Peter DeignerTargeted Metabolomics for Biomarker Discovery
Hans-Peter Deigner, David P. Enot, Matthias Kohl, Ignatius E. Igwe, Therese Koal, Michael Bauer, Guido DallmannUse of Endogenous Metabolites for Early Diagnosing Sepsis


Johannes Winning, Julia Reichel, Yvonne Eisenhut, Jürg Hamacher, Matthias Kohl, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Wolfgang LöscheAnti-platelet drugs and outcome in severe infection: Clinical impact and underlying mechanisms
Ralf A. Claus, Michael J. Dorer, Alexander C. Bunck, Hans-Peter DeignerInhibition of Sphingomyelin Hydrolysis: Targeting the Lipid Mediator Ceramide as a Key Regulator of Cellular Fate
Salvatore Cuzzocrea, Hans-Peter Deigner, Tiziana Genovese, Emanuela Mazzon, Emanuela Esposito, Concetta Crisafulli, Rosanna Di Paola, Placido Bramanti, George Matuschak, Daniela SalveminiInhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury
Hans-Peter Deigner, Matthias KohlThe molecular sepsis signature


Ralf Kinscherf, Hans-Peter DeignerApoptogenic Signal Transduction in Arteriosclerosis-Associated Cells – Opportunities for Future Therapy?
Hans-Peter Deigner, Albin HermetterOxidized phospholipids: emerging lipid mediators in pathophysiology


Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Dan Turcanu, Helmut Heinle, Wulf Dröge, Jürgen Metz, Ralf KinscherfIncreased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males
Hans-Peter Deigner, E. Gulbins, Ralf A. ClausSphingolipid Metabolism in Systemic Inflammation


Florian Setzer, Volker Oberle, Markus Bläss, Eva Möller, Stefan Rußwurm, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Konrad Reinhart, Wolfgang LöschePlatelet-derived microvesicles induce differential gene expression in monocytic cells: A DNA microarray study
M. Harz, Ralf A. Claus, Clemens L. Bockmeyer, M. Baum, P. Rösch, Karim Kentouche, Hans-Peter Deigner, Jürgen PoppUV-Resonance Raman Spectroscopic Study of Human Plasma of Healthy Donors and Patients with Thrombotic Microangiopathy


Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Wulf Dröge, Jürgen Metz, Ralf KinscherfIncreased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects
Ralf A. Claus, Alexander C. Bunck, Clemens L. Bockmeyer, Frank M. Brunkhorst, Wolfgang Lösche, Ralf Kinscherf, Hans-Peter DeignerRole of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis
Ralf A. Claus, Annette Wüstholz, Stefan Müller, Clemens L. Bockmeyer, Norman H. Riedel, Ralf Kinscherf, Hans-Peter DeignerSynthesis and Antiapoptotic Activity of a Novel Analogue of the Neutral Sphingomyelinase Inhibitor Scyphostatin
Thomas Hilberg, Hans-Peter Deigner, Eva Möller, Ralf A. Claus, Andriy Ruryk, Doreen Gläser, Julien Landre, Frank M. Brunkhorst, Konrad Reinhart, Holger H. Gabriel, Stefan RußwurmTranscription in response to physical stress - clues to the molecular mechanisms of exercise-induced asthma
Ralf A. Claus, Clemens L. Bockmeyer, Karim Kentouche, Matthias W. Sieber, Volker Oberle, Roland Kaufmann, Hans-Peter Deigner, Wolfgang LöscheTranscriptional regulation of ADAMTS13
V. Tomic, Stefan Rußwurm, Eva Möller, Ralf A. Claus, Markus Bläss, Frank M. Brunkhorst, M. Brügel, K. Bode, F. Bloos, J. Wippermann, T. Wahlers, Hans-Peter Deigner, J. Thiery, Konrad Reinhart, Michael BauerTranscriptomic and Proteomic Patterns of Systemic Inflammation in On-Pump and Off-Pump Coronary Artery Bypass Grafting


Miroslav Prucha, Andriy Ruryk, Hinnerk Boriss, Eva Möller, Roman Zazula, Ivan Herold, Ralf A. Claus, Konrad Reinhart, Hans-Peter Deigner, Stefan RußwurmExpression profiling: toward an application in sepsis diagnostics
Alexandra Loidl, Ralf A. Claus, Elisabeth Ingolic, Hans-Peter Deigner, Albin HermetterRole of ceramide in activation of stress-associated MAP kinases by minimally modified LDL in vascular smooth muscle cells


Ralf Kinscherf, Konstantinos Cafaltzis, Falk Röder, Wulf Hildebrandt, Lutz Edler, Hans-Peter Deigner, Raoul Breitkreutz, Giso Feussner, Jörg Kreuzer, Egon Werle, Gerd Michel, Jürgen Metz, Wulf DrögeCholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox status in hyperlipidemic subjects
Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Jürgen MetzHypercholesterolemia-Induced Long-Term Increase of Macrophages in the Myocardium of New Zealand White Rabbits
Stefan Rußwurm, Hans-Peter Deigner, Konrad ReinhartMicroarray technology in sepsis: tool or toy?
Alexandra Loidl, Eva Sevcsik, Gernot Riesenhuber, Hans-Peter Deigner, Albin HermetterOxidized Phospholipids in Minimally Modified Low Density Lipoprotein Induce Apoptotic Signaling via Activation of Acid Sphingomyelinase in Arterial Smooth Muscle Cells


Alexandra Loidl, Ralf A. Claus, Hans-Peter Deigner, Albin HermetterHigh-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates


Hans-Peter Deigner, Ralf A. Claus, Gabriel A. Bonaterra, Christof Gehrke, Nilofar Bibak, Markus Bläss, Michael Cantz, Jürgen Metz, Ralf KinscherfCeramide induces aSMase expression: implications for oxLDL-induced apoptosis
Helmut Weicker, Ralf Kinscherf, Karin Diserens, Hans-Peter Deigner, Heiko StrüderPhysiology and pathophysiology of basalganglia: impact on motor system function
Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Matthias Wiederhold, Andrea Luber, Peter F. Zipfel, Hans-Peter Deigner, Konrad ReinhartProcalcitonin and CGRP-I mRNA expression in various human tissues
Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Peter F. Zipfel, Hans-Peter Deigner, Konrad ReinhartVarious human tissues express procalcitonin and CGRP-I mRNA


Ralf A. Claus, Ralf Kinscherf, Christof Gehrke, Gabriel A. Bonaterra, Purusotam Basnet, Jürgen Metz, Hans-Peter DeignerAntiapoptotic Effects of Propolis Extract and Propol on Human Macrophages Exposed to Minimally Modified Low Density Lipoprotein
Hans-Peter Deigner, Uwe Haberkorn, Ralf KinscherfApoptosis modulators in the therapy of neurodegenerative diseases
Ralf A. Claus, Stefan Rußwurm, M. Meisner, Ralf Kinscherf, Hans-Peter DeignerModulation of the ceramide level, a novel therapeutic concept?


Ralf Kinscherf, Martin Wagner, Huse Kamencic, Gabriel A. Bonaterra, Dongming Hou, Rainer A. Schiele, Hans-Peter Deigner, Jürgen MetzCharacterization of apoptotic macrophages in atheromatous tissue of humans and heritable hyperlipidemic rabbits
Ilmars Stonans, Elita Stonane, Stefan Rußwurm, Hans-Peter Deigner, Konrad J. Böhm, Matthias Wiederhold, Lothar Jäger, Konrad ReinhartHepG2 Human Hepatoma Cells Express Multiple Cytokine Genes
Hans-Peter Deigner, Ralf KinscherfModulating apoptosis: current applications and prospects for future drug development
Hans-Peter Deigner, Ralf Kinscherf, Ralf A. Claus, Beatrix Fyrnys, Christopher Blencowe, Albin HermetterNovel reversible, irreversible and fluorescent inhibitors of platelet-activating factor acetylhydrolase as mechanistic probes


Ralf Kinscherf, Ralf A. Claus, Martin Wagner, Christof Gehrke, Huse Kamencic, Dongming Hou, Olaf Nauen, Walther Schmiedt, Gyula Kovacs, Johannes Pill, Jürgen Metz, Hans-Peter DeignerApoptosis caused by oxidized LDL is manganese superoxide dismutase and p53 dependent
Walther Schmiedt, Ralf Kinscherf, Hans-Peter Deigner, Huse Kamencic, Olaf Nauen, Juliane Kilo, Hellmut Oelert, Jürgen Metz, Sucharit BhakdiComplement C6 Deficiency Protects Against Diet-Induced Atherosclerosis in Rabbits


Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Jürgen MetzDer Einfluß von Veränderungen des Blut-Cholesterinspiegels auf Makrophagen im Myokard von Kaninchen
Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Michael Schrader, Jürgen MetzEffect of alterations of blood cholesterol levels on macrophages in the myocardium of New Zealand White rabbits
Ralf Kinscherf, Hans-Peter Deigner, Claus Usinger, Johannes Pill, Martin Wagner, Huse Kamencic, Dongming Hou, Min Chen, Walther Schmiedt, Michael Schrader, Gyula Kovacs, Kanefusa Kato, Jürgen MetzInduction of mitochondrial manganese superoxide dismutase in macrophages by oxidized LDL: its relevance in atherosclerosis of humans and heritable hyperlipidemic rabbits
Ralf Kinscherf, Walther Schmiedt, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, S. Bhakdi, Jürgen MetzKomplement C6-Defizienz führt zu einem signifikant geringeren Anstieg von Makrophagen (CR3/43) und arteriosklerotischen Plaques in Cholesterin-gefütterten Kaninchen
Ralf Kinscherf, Ralf A. Claus, Hans-Peter Deigner, Olaf Nauen, Christoph Gehrke, Albin Hermetter, Stefan Rußwurm, Volker Daniel, Volker Hack, Jürgen MetzModified low density lipoprotein delivers substrate for ceramide formation and stimulates the sphingomyelin-ceramide pathway in human macrophages
Hans-Peter Deigner, Ralf A. Claus, Ralf KinscherfModifiziertes LDL als Substratquelle für die Bildung von Ceramid
Beatrix Fyrnys, Ralf A. Claus, Gert Wolf, Hans-Peter DeignerOxidized Low Density Lipoprotein Stimulates Protein Kinase C (PKC) Activity and Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Cells


Ralf A. Claus, Beatrix Fyrnys, Hans-Peter Deigner, Gert WolfOxidized Low-Density Lipoprotein Stimulates Protein Kinase C (PKC) and Induces Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Macrophage-Like Cells
M. A. Pajares, L. Alvarez, B. Gil Perez, M. L. Martinez Chantar, J. Mingorance, E. Sanchez Gongora, Hans-Peter Deigner, M. Avila, J. M. MatoRegulation and structure of rat liver S-adenosylmethionine synthethase, a target enzyme for studies in liver injury
Hans-Peter Deigner, Ralf A. ClausStimulation of mitogen activated protein kinase by LDL and oxLDL in human U-937 macrophage-like cells
Hans-Peter Deigner, Ralf A. Clausox LDL induzierte Tyrosinkinase-Aktivität


Hans-Peter Deigner, Christian E. Freyberg, S. LauferDistribution and excretion of [14C]-labelled [2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5- yl]- [2'-14C]-acetic acid in rats
Christopher Blencowe, Albin Hermetter, Gert M. Kostner, Hans-Peter DeignerEnhanced Association of Platelet-activating Factor Acetylhydrolase with Lipoprotein (a) in Comparison with Low Density Lipoprotein
Hans-Peter Deigner, Christopher Blencowe, Christian E. FreybergPrevalence of steric restrictions in enzymatic nitrile-hydrolysis of a preparation from Rhodococcus sp. 409
Hans-Peter Deigner, Jose M. Mato, Maria A. PajaresStudy of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP
Beatrix Fyrnys, Christopher Blencowe, Hans-Peter DeignerSusceptibility of phospholipids of oxidizing LDL to enzymatic hydrolysis modulates uptake by P388D1 macrophage-like cells


Hans-Peter Deigner, G. Wolf, U. Ohlenmacher, J. Reichling1'-Hydroxyeugenol- and coniferyl alcohol derivatives as effective inhibitors of 5-lipoxygenase and Cu(2+)-mediated low density lipoprotein oxidation. Evidence for a dual mechanism
Hans-Peter Deigner, G. WolfOxidativ modifiziertes LDL und seine mögliche Rolle in der Atherogenese


Hans-Peter Deigner, Christian E. Freyberg, R. HeckChemoenzymatic synthesis of carbon-14 labelled antioxidants
Hans-Peter Deigner, Hans A. DreselEffect of platelet activating factor on the kinetics of LDL oxidation in vitro
Hans-Peter Deigner, Beatrix FyrnysSynthesis of [32P]labelled 1-O-alkyl-2-desoxy-2-amino-sn′-glycero-3-phosphocholines


Hans-Peter Deigner, Beatrix FyrnysRapid synthesis of 2-desoxy-2-amino-3-phosphocholine-glycerinic-acid-alkylester, 1-alkyl-1-desoxy- and 1-O-alkyl-2-desoxy-2-amino-sn-glycero-3-phosphocholines, -3-phospho-N,N′-dimethylethanolamine and -3-phospho-Fmoc-serine-methylester
Hans-Peter Deigner, E. Friedrich, H. Sinn, Hans A. DreselScavenging of lipid peroxidation products from oxidizing LDL by albumin alters the plasma half-life of a fraction of oxidized LDL particles


Hans-Peter DeignerÜber eine mögliche Rolle von Proteinen bei der LDL-Oxidation


Richard Neidlein, Take Constantinescu, Claus Krieger, Hans-Peter DeignerA Convenient Solid-Support Procedure for the Synthesis of Symmetric Disulphides. The Configuration of Aromatic Carben Atoms in the 1,6-Methano[10]annulene Framework
Hans A. Dresel, Hans-Peter Deigner, J. Frübis, K. Strein, G. SchettlerLDL-metabolism of the arterial wall-new implications for atherogenesis


Hans-Peter Deigner, Wing C. Law, Francisco J. Canada, Robert R. RandoMembranes as the energy source in the endergonic transformation of vitamin A to 11-cis-retinols


Richard Neidlein, Hans-Peter DeignerBiotransformation of 4-Oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[ 2,6endo]dec-8-en-3on an der Ratte
Richard Neidlein, Hans-Peter Deigner, W. KramerIn vivo- und in vitro-Untersuchung von synthetischem Vergleichsmaterial zu Stoffwechselprodukten von 4-0xa-5-exo-(N-methylcarbamoyloxy-tricyclo[,6endo]dec-8-en-3d-oenr Ratte
Richard Neidlein, Hans-Peter DeignerPharmakokinetik von 4-oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[5:2.1.0. 2,6-endo]dec-8-en-3on an der Ratte