Zur Person
Forschungsfelder und / oder Lehrgebiete
Lehrgebiete:
- Biomarker
- Molekulare Diagnostik
- Metabolomics
- Biobanking
- Spezielle Aspekte der Systembiologie
- Gastwissenschaftler Fraunhofer Gesellschaft, Institut für Zelltherapie und Immunologie (IZI), EXIM, Rostock
- Gründungsmitglied und Mitglied des Exekutivkomitees der Europäischen Gesellschaft für Biopreservation und Biobanking (ESBB, www.esbb.org)
Publikationen
Deigner, Hans-Peter
2024 | |||
| Jessica Jung-Fittkau, Josef Diebold, Andrea Kruse, Hans-Peter Deigner, Magnus S. Schmidt | Measurement of the reaction enthalpy of CO2 in aqueous solutions with thermographic and gravimetric methods | Research Square, 2024 | BibTeX | RIS DOI |
| Isabel Quint, Jonathan Simantzik, Lars Kaiser, Stefan Laufer, Rene Csuk, David Smith, Matthias Kohl, Hans-Peter Deigner | Ready-to-use nanopore platform for label-free small molecule quantification: Ethanolamine as first example | Nanomedicine: Nanotechnology, Biology and Medicine, 55.2024(January), 2024 | BibTeX | RIS DOI |
| Simone Rentschler, Max Borgolte, Rene Csuk, Stefan Laufer, Hans-Peter Deigner | Toward more sustainable enzyme reactions: enhancing kinetics by polydimethylacrylamide implementation | Green Chemistry, 26.2024(3), pp. 1653-1659, 2024 | BibTeX | RIS DOI |
2023 | |||
| Suihong Liu, Lijia Cheng, Yakui Liu, Haiguang Zhang, Yongteng Song, Jeong-Hui Park, Khandmaa Dashnyam, Jung-Hwan Lee, Fouad Al-Hakim Khalak, Oliver Riester, Zheng Shi, Serge Ostrovidov, Hirokazu Kaji, Hans-Peter Deigner, Jose Luis Pedraz, Jonathan C. Knowles, Qingxi Hu, Hae-Won Kim, Murugan Ramalingam | 3D Bioprinting tissue analogs: Current development and translational implications | Journal of Tissue Engineering, 14.2023(Online First), 2023 | BibTeX | RIS DOIURN |
| Benjamin Brandes, Sophie Hoenke, Christian Schultz, Hans-Peter Deigner, Rene Csuk | Converting bile acids into mitocans | Steroids, 189.2023(January), p. 10, 2023 | BibTeX | RIS DOIURN |
| Simone Rentschler, Max Borgolte, Alexander Filbert, Stefan Laufer, Hans-Peter Deigner | Highly efficient β-lactamase assay applying Poly-Dimethylacrylamide-based surface functionalization with β-lactam antibiotics and β-lactamase inhibitors | Lab on a Chip, pp. 5120-5130, 2023 | BibTeX | RIS DOI |
| Murugan Ramalingam, Abinaya Jaisankar, Lijia Cheng, Sasirekha Krishnan, Liang Lan, Anwarul Hassan, Hilal Turkoglu Sasmazel, Hirokazu Kaji, Hans-Peter Deigner, Jose L. Pedraz, Hae-Won Kim, Zheng Shi, Giovanna Marrazza | Impact of nanotechnology on conventional and artificial intelligence-based biosensing strategies for the detection of viruses | Discover Nano, 18.2023(1), 2023 | BibTeX | RIS DOIURN |
| Isabel Quint, Jonathan Simantzik, Lars Kaiser, Stefan Laufer, Rene Csuk, David Smith, Matthias Kohl, Hans-Peter Deigner | Ready-to-use nanopore platform for ethanolamine quantification using an aptamer-based strand displacement assay | bioRXiv: The Preprint Server for Biology, 2023 | BibTeX | RIS DOI |
| Bassam Abu Thaher, Ihab Al-Masri, Kanan Wahedy, Rami Morjan, Saeb Aliwaini, Iman M. Al atter, Aayat A. Elmabhouh, Areej khaled AL ibwaini, Basem Queshta, Claus Jacob, Hans-Peter Deigner, Saba L. Alkhaldi | Synthesis and bioassay of 3-Aryl -1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]- triazin-4(3H)-ones as anti-cancer agents | Naunyn-Schmiedeberg's Archives of Pharmacology, 396.2023(8), pp. 1797-1810, 2023 | BibTeX | RIS DOI |
2022 | |||
| Max Borgolte, Isabel Quint, Lars Kaiser, Rene Csuk, Hans-Peter Deigner | A Fluorescence-Based Competitive Antibody Binding Assay for Kynurenine, a Potential Biomarker of Kidney Transplant Failure | Diagnostics, 12.2022(6), 2022 | BibTeX | RIS DOI |
| Axel Franz, Hacer Yapicioglu-Yildizdas, Erdal Taskin, Akan Yaman, Yalcin Celik, Huseyin Simsek, Serif Hamitoglu, Nesil Aydinol, Elif Keles, Matthias Keller, Manon Benders, Floris Groenendaal, Kim Anninck, Lena Hellström-Westas, Ola Saugstad, Neil Marlow, Hans-Peter Deigner, Matthias Kohl, Ron Meyer, Achim Plum, Carola Steins-Rang, Peter Bartmann | Asphyxia Associated Metabolite Biomarker Investigation (AAMBI). Short-term clinical outcomes and at the age of 22 to 42 months | Journal of Neonatal-Perinatal Medicine, 15.2022(2), pp. 431-432, 2022 | BibTeX | RIS DOIURN |
| Marie Kozubek, Sophie Hoenke, Hans-Peter Deigner, Rene Csuk | Betulinic acid and glycyrrhetinic acid derived piperazinyl spacered rhodamine B conjugates are highly cytotoxic and necrotic | Results in Chemistry, Vol.4.2022, 2022 | BibTeX | RIS DOIURN |
| Angelika Czajkowska, Defne I. Dayi, Helga Weinschrott, Hans-Peter Deigner, Magnus S. Schmidt | Chemical decarboxylation kinetics and identification of amino acid standards by benchtop NMR spectroscopy | Chemical Papers, 76.2022(2), pp. 879-888, 2022 | BibTeX | RIS DOIURN |
| Jessica Jung, Lars Kaiser, Hans-Peter Deigner, Magnus S. Schmidt | Continuous synthesis of bromoalkyl glycosides by Fischer glycosylation in a microreactor | Journal of Flow Chemistry, 12.2022(1), pp. 9-15, 2022 | BibTeX | RIS DOIURN |
| Alexandra Zorin, Lukas Klenk, Tonia Mack, Hans-Peter Deigner, Magnus S. Schmidt | Current Synthetic Approaches to the Synthesis of Carbasugars from Non-Carbohydrate Sources | Topics in Current Chemistry, Vol.380.2022, 2022 | BibTeX | RIS DOIURN |
| Oliver Riester, Stefan Laufer, Hans-Peter Deigner | Direct 3D printed biocompatible microfluidics: assessment of human mesenchymal stem cell differentiation and cytotoxic drug screening in a dynamic culture system | Journal of Nanobiotechnology, Vol.20.2022, 2022 | BibTeX | RIS DOIURN |
| Toni C. Denner, Sophie Hoenke, Oliver Kraft, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | Hydroxyethylamide substituted triterpenoic acids hold good cytotoxicity for human tumor cells | Results in Chemistry, 4.2022(January), 2022 | BibTeX | RIS DOIURN |
| Weronika Schary, Filip Paskali, Simone Rentschler, Christoph Ruppert, Gabriel E. Wagner, Ivo Steinmetz, Hans-Peter Deigner, Matthias Kohl | Open-Source, Adaptable, All-in-One Smartphone-Based System for Quantitative Analysis of Point-of-Care Diagnostics | Diagnostics, 12.2022(3), 2022 | BibTeX | RIS DOIURN |
| Markus Blaess, Oliver Sommerfeld, Rene Csuk, Hans-Peter Deigner | Small molecules targeting endolysosomal acidification and signaling in sepsis and severe SARS-CoV-2 infection/COVID-19 | Exploration of Immunology, 2.2022(4), pp. 484-509, 2022 | BibTeX | RIS DOIURN |
| Oliver Riester, Pia Burkhardtsmaier, Yuna Gurung, Stefan Laufer, Hans-Peter Deigner, Magnus S. Schmidt | Synergy of R‑(–)carvone and cyclohexenone‑based carbasugar precursors with antibiotics to enhance antibiotic potency and inhibit biofilm formation | Scientific Reports, Vol.12.2022, 2022 | BibTeX | RIS DOIURN |
| Benjamin Brandes, Sophie Hoenke, Niclas Starke, Immo Serbian, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | Synthesis and cytotoxicity of apoptosis-inducing N-heterocyclic triterpene amides | European Journal of Medicinal Chemistry Reports, Vol.6.2022, 2022 | BibTeX | RIS DOIURN |
| Marie Kozubek, Sophie Hoenke, Theresa Schmidt, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | Synthesis and cytotoxicity of betulin and betulinic acid derived 30-oxo-amides | Steroids, 182.2022(June), 2022 | BibTeX | RIS DOI |
| Max Borgolte, Oliver Riester, Isabel Quint, Felix Blendinger, Volker Bucher, Stefan Laufer, Rene Csuk, Luca Scotti, Hans-Peter Deigner | Synthesis of a biocompatible benzophenone-substituted chitosan hydrogel as novel coating for PEEK with extraordinary strong antibacterial and anti-biofilm properties | MaterialsToday Chemistry, Vol.26.2022, 2022 | BibTeX | RIS DOIURN |
| Niels V. Heise, Jördis-Ann Schüler, Torje E. Orlamünde, Benjamin Brandes, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | Triterpenoid cholinesterase inhibitors that might improve gait disturbances in Parkinson's disease patients | Mediterranean Journal of Chemistry, 12.2022(2), pp. 188-200, 2022 | BibTeX | RIS |
| Susanne Jacksch, Christoph König, Dominik Kaiser, Lars Kaiser, Mirko Weide, Sylvia Schnell, Hans-Peter Deigner, Markus Egert | Using OMICS-technologies to unravel the mystery of malodour formation in washing machines and on washed laundry | VAAM Jahrestagung, Annual Conference of the Association for General and Applied Microbiology 2022 digital, 21. - 23. Feburuar 2022, Düsseldorf/Jülich, Germany, 2022 | BibTeX | RIS 978-3-948023-22-5, |
2021 | |||
| Benjamin Brandes, Sophie Hoenke, Michael Türk, Björn Weber, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | A unified strategy for the synthesis of amorfrutins A and B and evaluation of their cytotoxicity | Mediterranean Journal of Chemistry, 11.2021(1), pp. 23-31, 2021 | BibTeX | RIS DOI |
| Marie Kozubek, Linda Höhlich, Sophie Hoenke, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | Apoptotic activity of substituted 3-O-acetyl-betulinic acid benzylamides | European Journal of Medicinal Chemistry Reports, 3.2021(December), 2021 | BibTeX | RIS DOIURN |
| Abid A. Khan, Sana Khan, Suhaib Khan, Simone Rentschler, Stefan Laufer, Hans-Peter Deigner | Biosynthesis of iron oxide magnetic nanoparticles using clinically isolated Pseudomonas aeruginosa | Scientific reports, Vol.11.2021, 2021 | BibTeX | RIS DOIURN |
| Oliver Riester, Max Borgolte, Rene Csuk, Hans-Peter Deigner | Challenges in Bone Tissue Regeneration: Stem Cell Therapy, Biofunctionality and Antimicrobial Properties of Novel Materials and Its Evolution | International Journal of Molecular Sciences, 22.2021(1 Article 192), 2021 | BibTeX | RIS DOI |
| Mostafa Mahmoud, Christoph Ruppert, Simone Rentschler, Stefan Laufer, Hans-Peter Deigner | Combining aptamers and antibodies: lateral flow quantification for thrombin and interleukin-6 with smartphone readout | Sensors and Actuators B: Chemical, 333.2021(April), 2021 | BibTeX | RIS DOI |
| Theresa Schmidt, Niels Heise, Kurt Merzweiler, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | Concise Synthesis of Both Enantiomers of Pilocarpine | Molecules, 26.2021(12), 2021 | BibTeX | RIS DOI |
| Saeb Aliwaini, Bassam Abu Thaher, Ihab Al-Masri, Nabil Shurrab, Said El-Kurdi, Dieter Schollmeyer, Basem Qeshta, Mariam Ghunaim, Rene Csuk, Stefan Laufer, Lars Kaiser, Hans-Peter Deigner | Design, Synthesis and Biological Evaluation of Novel Pyrazolo[1,2,4]triazolopyrimidine Derivatives as Potential Anticancer Agents | Molecules, 26.2021(13), 2021 | BibTeX | RIS DOIURN |
| Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Rene Csuk, Hans-Peter Deigner | Drug triggered pruritus, rash, papules, and blisters – is AGEP a clash of an altered sphingolipid-metabolism and lysosomotropism of drugs accumulating in the skin? | Lipids in Health and Disease, Vol.20.2021, 2021 | BibTeX | RIS DOIURN |
| Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Rene Csuk, Hans-Peter Deigner | Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19 | International Journal of Molecular Sciences, 22.2021(4 Article 1797), 2021 | BibTeX | RIS DOI |
| Said El-Kurdi, Bassam Abu Thaher, Kanan M. Wahedy, Dieter Schollmeyer, Levin Nopper, Oliver Riester, Hans-Peter Deigner | Efficient Synthesis and X-ray Structure of [1,2,4]Triazolo[4,3-a]pyridines via Oxidative Cyclization Using N-Chlorosuccinimide (NCS) | Crystals, 11.2021(10), 2021 | BibTeX | RIS DOIURN |
| Simone Rentschler, Lars Kaiser, Hans-Peter Deigner | Emerging Options for the Diagnosis of Bacterial Infections and the Characterization of Antimicrobial Resistance | International Journal of Molecular Sciences, 22.2021(1 Article 456), 2021 | BibTeX | RIS DOI |
| Teresa Schätzl, Lars Kaiser, Hans-Peter Deigner | Facioscapulohumeral muscular dystrophy: genetics, gene activation and downstream signalling with regard to recent therapeutic approaches: an update | Orphanet Journal of Rare Diseases, 16.2021(Artikel 129), 2021 | BibTeX | RIS DOIURN |
| Lars Kaiser, Isabel Quint, Rene Csuk, Manfred Jung, Hans-Peter Deigner | Lineage-Selective Disturbance of Early Human Hematopoietic Progenitor Cell Differentiation by the Commonly Used Plasticizer Di-2-ethylhexyl Phthalate via Reactive Oxygen Species: Fatty Acid Oxidation Makes the Difference | Cells, 10.2021(10), 2021 | BibTeX | RIS DOIURN |
| Max Borgolte, Oliver Riester, Tereza Kacerova, Simone Rentschler, Magnus S. Schmidt, Susanne Jacksch, Markus Egert, Stefan Laufer, Rene Csuk, Hans-Peter Deigner | Methacryloyl-GlcNAc Derivatives Copolymerized with Dimethacrylamide as a Novel Antibacterial and Biocompatible Coating | Pharmaceutics, 10.2021(10), 2021 | BibTeX | RIS DOIURN |
| Weronika Schary, Filip Paskali, Simone Rentschler, Christoph Ruppert, Gabriel Wagner, Ivo Steinmetz, Hans-Peter Deigner, Matthias Kohl | Open-source, Adaptable, All-in-one Smartphone-based System for Quantitative Analysis of Point-of-care Diagnostics | Research Square, 2021 | BibTeX | RIS DOI |
| Abid A. Khan, Khanzadi N. Manzoor, Aamir Sultan, Maria Saeed, Mahrukh Rafique, Sameen Noushad, Ayesha Talib, Simone Rentschler, Hans-Peter Deigner | Pulling the Brakes on Fast and Furious Multiple Drug-Resistant (MDR) Bacteria | International Journal of Molecular Sciences, 22.2021(2 Article 859), 2021 | BibTeX | RIS DOI |
| Nico Laur, Lars Kaiser, Hans-Peter Deigner, Ralf Kinscherf | Sequential Analysis of Trace Elements in a Micro Volume Urine Sample Using Inductively Coupled Plasma Mass Spectrometry | Applied Scienes, 11.2021(9 Article 3740), 2021 | BibTeX | RIS DOI |
| Benjamin Brandes, Jan H. Halz, Kurt Merzweiler, Hans-Peter Deigner, Rene Csuk | Synthesis and structure of azelastine-N-oxides | Journal of Molecular Structure, 2021 | BibTeX | RIS DOIURN |
| Alexander M. König, Ulrich Köhler, Olaf Hildebrandt, Hans Schwarzbach, Lena Hannemann, Raphael Boneberg, Johannes T. Heverhagen, Andreas H. Mahnken, Malte Keller, Peter H. Kann, Hans-Peter Deigner, Nico Laur, Ralf Kinscherf, Wulf Hildebrandt | The Effect of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Skeletal Muscle Lipid Content in Obese and Nonobese Men | Journal of the Endocrine Society, 5.2021(8), 2021 | BibTeX | RIS DOIURN |
| Sophie Hoenke, Martin A. Christoph, Sander Friedrich, Niels Heise, Benjamin Brandes, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | The Presence of a Cyclohexyldiamine Moiety Confers Cytotoxicity to Pentacyclic Triterpenoids | Molecules, 26.2021(7), 2021 | BibTeX | RIS DOIURN |
| Niels Heise, Sophie Hoenke, Vivienne Simon, Hans-Peter Deigner, Ahmed Al-Harrasi, Rene Csuk | Type and position of linkage govern the cytotoxicity of oleanolic acid rhodamine B hybrids | Steroids, 172.2021(August), 2021 | BibTeX | RIS DOI |
| Immo Serbian, Erik Prell, Claudia Fischer, Hans-Peter Deigner, Rene Csuk | n-Propyl 6-amino-2,6-dideoxy-2,2-difluoro-β-D-glucopyranoside is a good inhibitor for the β-galactosidase from E. coli | Medicinal Chemistry Research, 30.2021(5), pp. 1099-1107, 2021 | BibTeX | RIS DOIURN |
2020 | |||
| Sophie Hoenke, Niels V. Heise, Michael Kahnt, Hans-Peter Deigner, Rene Csuk | Betulinic acid derived amides are highly cytotoxic, apoptotic and selective | European Journal of Medicinal Chemistry, 207.2020(December Article 112815), 2020 | BibTeX | RIS DOI |
| Markus Blaess, Lars Kaiser, Martin Sauer, Rene Csuk, Hans-Peter Deigner | COVID-19/SARS-CoV-2 Infection: Lysosomes and Lysosomotropism Implicate New Treatment Strategies and Personal Risks | International Journal of Molecular Sciences, 21.2020(14 Article 4953), 2020 | BibTeX | RIS DOIURN |
| Christoph Ruppert, Lars Kaiser, Lisa Jacob, Stefan Laufer, Matthias Kohl, Hans-Peter Deigner | Duplex Shiny app quantification of the sepsis biomarkers C-reactive protein and interleukin-6 in a fast quantum dot labeled lateral flow assay | Journal of Nanobiotechnology, 18.2020(Artikel 130), 2020 | BibTeX | RIS DOIURN |
| Nico Laur, Ralf Kinscherf, Karolina Pomytkin, Lars Kaiser, Otto Knes, Hans-Peter Deigner | ICP-MS trace element analysis in serum and whole blood | PLOS ONE, 15.2020(5 Article e0233357), 2020 | BibTeX | RIS DOIURN |
| Markus Bläss, Lars Kaiser, Martin Sauer, Hans-Peter Deigner | Lysosomotropic Active Compounds — Hidden Protection against COVID-19 / SARS-CoV-2 Infection? | Preprints, 2020 | BibTeX | RIS DOI |
| Lars Kaiser, Helga Weinschrott, Isabel Quint, Markus Blaess, Rene Csuk, Manfred Jung, Matthias Kohl, Hans-Peter Deigner | Metabolite Patterns in Human Myeloid Hematopoiesis Result from Lineage-Dependent Active Metabolic Pathways | International Journal of Molecular Sciences, 21.2020(17 Article 6092), 2020 | BibTeX | RIS DOIURN |
| Hans-Peter Deigner, Mostafa Mahmoud | Method for the detection and quantification of small Molecules and Fluidic platform for performing the same | 2020 | BibTeX | RIS |
| Sophie Hoenke, Immo Serbian, Hans-Peter Deigner, Rene Csuk | Mitocanic Di- and Triterpenoid Rhodamine B Conjugates | Molecules, 25.2020(22), 2020 | BibTeX | RIS DOIURN |
| Markus Blaess, Lars Kaiser, Oliver Sommerfeld, Simone Rentschler, Rene Csuk, Hans-Peter Deigner | Rational Drug Repurposing: Focus on Lysosomotropism, Targets in Disease Process, Drug Profile, and Pulmonary Tissue Accumulation in SARS-CoV-2 Infection/COVID-19 | Frontiers in Pharmacology, 11.2020(November Article 584881), 2020 | BibTeX | RIS DOIURN |
| Benjamin Brandes, Lukas Koch, Sophie Hoenke, Hans-Peter Deigner, Rene Csuk | The presence of a cationic center is not alone decisive for the cytotoxicity of triterpene carboxylic acid amides | Steroids, 163.2020(November Article 108713), 2020 | BibTeX | RIS DOI |
2019 | |||
| Christoph Ruppert, Navneet Phogat, Stefan Laufer, Matthias Kohl, Hans-Peter Deigner | A smartphone readout system for gold nanoparticle-based lateral flow assays: application to monitoring of digoxigenin | Microchimica Acta, 186.2019(Aufsatz 119), 2019 | BibTeX | RIS DOIURN |
| Mostafa Mahmoud, Stefan Laufer, Hans-Peter Deigner | An aptamer based thermofluorimetric assay for ethanolamine | Biochimie, 158.2019(March), pp. 233-237, 2019 | BibTeX | RIS DOI |
| Mostafa Mahmoud, Stefan Laufer, Hans-Peter Deigner | Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument | Data in Brief, 24.2019(Aufsatz 103946), 2019 | BibTeX | RIS DOIURN |
| Markus Blaess, Hans-Peter Deigner | Derailed Ceramide Metabolism in Atopic Dermatitis (AD): A Causal Starting Point for a Personalized (Basic) Therapy | International Journal of Molecular Sciences, 20.2019(16 Article 3967), 2019 | BibTeX | RIS DOIURN |
| Markus Blaess, Hans-Peter Deigner | Focusing on derailed cellular ceramide metabolism fosters recovery of atopic dermatitis lesions and psoriasis plaques | Journal der Deutschen Dermatologischen Gesellschaft, 17.2019(S3), p. 176, 2019 | BibTeX | RIS DOI |
| Markus Blaess, Folker Wenzel, Hans-Peter Deigner | Recovery of derailed ceramide metabolism in atopic dermatitis: a successful topical off-label use of amitriptyline combined with linoleic acid | Journal der Deutschen Dermatologischen Gesellschaft, 17.2019(S3), p. 145, 2019 | BibTeX | RIS DOI |
| Rene Csuk, Hans-Peter Deigner | The potential of click reactions for the synthesis of bioactive triterpenes | Bioorganic & Medicinal Chemistry Letters, 29.2019(8), pp. 949-958, 2019 | BibTeX | RIS DOI |
| Mostafa Mahmoud, Stefan Laufer, Hans-Peter Deigner | Visual aptamer-based capillary assay for ethanolamine using magnetic particles and strand displacement | Microchimica Acta, 186.2019(Artikel 690), 2019 | BibTeX | RIS DOI |
2018 | |||
| Hans-Peter Deigner(Ed.), , Matthias Kohl(Ed.) | Precision Medicine: Tools and Quantitative Approaches | Academic Press: London, 978-0-12-805364-5, 2018 | BibTeX | RIS 978-0-12-805364-5, |
| Stephan Vilgis, Hans-Peter Deigner | Sequencing in Precision Medicine | Precision Medicine: Tools and Quantitative Approaches, Academic Press: London, pp. 79-102, 2018 | BibTeX | RIS 978-0-12-805364-5, |
| Lars Kaiser, Julia Weisser, Matthias Kohl, Hans-Peter Deigner | Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection | Scientific Reports, 8.2018(5628), 2018 | BibTeX | RIS DOIURN |
2017 | |||
| Kanan M. Wahedy, Bassam Abu Thaher, Dieter Schollmeyer, Ihab M. Almasri, Rami Y. Morjan, Basem Qeshta, Hans-Peter Deigner | Crystal structures of pure 3-(4-bromo-2-chlorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one and contaminated with 3-(4-bromophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one | Acta Crystallographica Section E: Crystallographic Communications, 73.2017(9), pp. 1341-1343, 2017 | BibTeX | RIS DOIURN |
| Hans-Peter Deigner, Matthias Kohl, Christoph Ruppert, Sowmya S. Perumbakkam, Lisa Jacob, Anika Schmidt | Diagnostische Schnelltests für die personalisierte Medizin | 2017 | BibTeX | RIS |
| Markus Bläss, Nelly Bibak, Ralf A. Claus, Matthias Kohl, Gabriel A. Bonaterra, Ralf Kinscherf, Stefan Laufer, Hans-Peter Deigner | NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation | European Journal of Medicinal Chemistry, pp. 1-32, 2017 | BibTeX | RIS DOI |
2016 | |||
| Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Kanan M. Wahedy, Ihab M. Almasri, Rami Y. Morjan, Hans-Peter Deigner | 1-(Pyridin-4-yl)-3-(2,4,6-trichlorophenyl)benz- [4,5]imidazo[1,2-d ][1,2,4]triazin-4(3H)-one | IUCr Data, 1.2016(10), 2016 | BibTeX | RIS DOIURN |
| Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Hans-Peter Deigner | 3-(2,4-Difluorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one | IUCr Data, 1.2016(9), 2016 | BibTeX | RIS DOIURN |
| Ha-Yeun Chung, Daniel C. Hupe, Gordon P. Otto, Marcel Sprenger, Alexander C. Bunck, Michael J. Dorer, Clemens L. Bockmeyer, Hans-Peter Deigner, Markus H. Gräler, Ralf A. Claus | Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis | Molecular Medicine, Vol.22.2016, pp. 412-423, 2016 | BibTeX | RIS DOIURN |
| Hans-Peter Deigner | Bimodal imaging and beyond: Editorial | Atherosclerosis, 254.2016(November), pp. 278-279, 2016 | BibTeX | RIS DOI |
| Basri Gülbakan, Riza Köksal Özgül, Ayse Yüzbasioglu, Matthias Kohl, Hans-Peter Deigner, Meral Özgüc | Discovery of biomarkers in rare diseases: innovative approaches by predictive and personalized medicine | The EPMA Journal, 7.2016(1), 2016 | BibTeX | RIS DOIURN |
| Mario Brameshuber, Eva Sevcsik, Benedikt K. Rossboth, Christina Manner, Hans-Peter Deigner, Begüm Peksel, Mária Péter, Zsolt Török, Albin Hermetter, Gerhard J. Schütz | Oxidized Phospholipids Inhibit the Formation of Cholesterol-Dependent Plasma Membrane Nanoplatforms | Biophysical Journal, 110.2016(1), pp. 205-213, 2016 | BibTeX | RIS DOI |
2015 | |||
| Mostafa Mahmoud, Hans-Peter Deigner | Aptamers in Diagnostics: Replacing or Complementing Antibodies? | Journal of Biochips & Tissue Chips, 5.2015(1), 2015 | BibTeX | RIS DOI |
| Markus Bläss, Ralf A. Claus, Hans-Peter Deigner | HPLC separation and ultrasensitive optical quantification of ceramide species applying 7-(diethylamino)coumarin-3-carbonyl azide derivatisation | Journal of Chromatography B, pp. 123-128, 2015 | BibTeX | RIS DOI |
| Christoph Ruppert, Matthias Kohl, Lisa Jacob, Hans-Peter Deigner | Multiplexing in Bioassays | Biosensors Journal, 4.2015(2), 2015 | BibTeX | RIS URN |
| Markus Bläss, H.P. Le, Ralf A. Claus, Matthias Kohl, Hans-Peter Deigner | Stereospecific Induction of Apoptosis in Tumor Cells via Endogenous C16-Ceramide and Distinct Transcripts | Cell Death Discovery, 1.2015(15013), 2015 | BibTeX | RIS DOIURN |
2013 | |||
| Nayla Jbeily, Iris Suckert, Falk A. Gonnert, Benedikt Acht, Clemens L. Bockmeyer, Sascha D. Grossmann, Markus Bläss, Anja Lüth, Hans-Peter Deigner, Michael Bauer, Ralf A. Claus | Hyperresponsiveness of mice defi cient in plasma-secreted sphingomyelinase reveals its pivotal role in early phase of host response | Journal of Lipid Research, 54.2013(2), pp. 410-424, 2013 | BibTeX | RIS DOIURN |
2012 | |||
| Martina Weber, Sandro Lambeck, Nadine Ding, Stefanie Henken, Matthias Kohl, Hans-Peter Deigner, David P. Enot, Ignatius E. Igwe, Lucien Frappart, Michael Kiehntopf, Ralf A. Claus, Thomas Kamradt, Debra Weih, Yoram Vodovotz, David E. Briles, Abiodun D. Ogunniyi, James C. Paton, Ulrich A. Maus, Michael Bauer | Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia | The FASEB journal, 26.2012(6), pp. 2424-2436, 2012 | BibTeX | RIS DOI |
| Ute Stemmer, Zsuzsanna A. Dunai, Daniel Koller, Gabriel Pürstinger, Elfriede Zenzmaier, Hans-Peter Deigner, Elma Aflaki, Dagmar Kratky, Albin Hermetter | Toxicity of oxidized phospholipids in cultured macrophages | Lipids in Health and Disease, 110.2012(11), 2012 | BibTeX | RIS DOIURN |
2011 | |||
| Matthias Kohl, S. Koch, Matthias Keller, Hans-Peter Deigner | Biochips: Bright Future in Clinical Dx? | Journal of Biochips & Tissue Chips, 2011 | BibTeX | RIS DOI |
| Matthias Keller, David P. Enot, Mark P. Hodson, Emeka I. Igwe, Hans-Peter Deigner, Justin Dean, Hayde Bolouri, Hendrik Hagberg, Carina Mallard | Inflammatory-Induced Hibernation in the Fetus: Priming of Fetal Sheep Metabolism Correlates with Developmental Brain Injury | PLOS ONE, 6.2011(12), 2011 | BibTeX | RIS DOIURN |
| Nigel Francis, See Heng Wong, Peter Hampson, Keqing Wang, Stephen P. Young, Hans-Peter Deigner, Michael Salmon, Dagmar Scheel-Toellner, Janet M. Lord | Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1813.2011(10), pp. 1822-1826, 2011 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Michael Bauer, Matthias Kohl | Method for in vitro diagnosing sepsis utilizing biomarker composed of more than two different types of endogenous biomolecules | 2011 | BibTeX | RIS |
| Hans-Peter Deigner, Matthias Kohl, Therese Koal, Ignatius E. Igwe, Guido Dallmann, Michael Bauer, David P. Enot | Use of bile acids for prediction of an onset of sepsis | 2011 | BibTeX | RIS |
2010 | |||
| Julien B. Landré, Markus Bläss, Matthias Kohl, Tina Schlicksbier, Andriy Ruryk, Ralf Kinscherf, Ralf A. Claus, Albin Hermetter, Matthias Keller, Michael Bauer, Hans-Peter Deigner | Addressable bipartite molecular hook (ABMH): Immobilized hairpin probes with sensitivity below 50 fM | Analytical Biochemistry, 397.2010(1), pp. 60-66, 2010 | BibTeX | RIS DOI |
| Ralf A. Claus, Gordon P. Otto, Hans-Peter Deigner, Michael Bauer | Approaching Clinical Reality: Markers for Monitoring Systemic Inflammation and Sepsis | Current Molecular Medicine, 10.2010(2), pp. 227-235, 2010 | BibTeX | RIS |
| Therese Koal, Hans-Peter Deigner | Challenges in Mass Spectrometry Based Targeted Metabolomics | Current Molecular Medicine, 10.2010(2), pp. 216-226, 2010 | BibTeX | RIS |
| Michael Urban, David P. Enot, Guido Dallmann, Lisa Körner, Verena Forcher, Peter Enoh, Therese Koal, Matthias Keller, Hans-Peter Deigner | Complexity and pitfalls of mass spectrometry-based targeted metabolomics in brain research | Analytical Biochemistry, 406.2010(2), pp. 124-131, 2010 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Ancha Baranova | Current Methods and Perspectives in Biomarker Discovery: Editorial | Current Molecular Medicine, 10.2010(2), pp. 113-114, 2010 | BibTeX | RIS DOI |
| Ronnaug Solberg, David P. Enot, Hans-Peter Deigner, Therese Koal, Sabine Scholl-Bürgi, Ola D. Saugstad, Matthias Keller | Metabolomic Analyses of Plasma Reveals New Insights into Asphyxia and Resuscitation in Pigs | PLOS ONE, 5.2010(3), 2010 | BibTeX | RIS DOIURN |
| Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal, Klaus Weinberger | Method for In Vitro Diagnosing a Complex Disease | 2010 | BibTeX | RIS |
| Hans-Peter Deigner, Matthias Kohl, David P. Enot, Therese Koal, Matthias Keller | Method for Predicting the Likelihood of an Onset of an Inflammation Associated Organ Failure | 2010 | BibTeX | RIS |
| Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal | Method for normalization in metabolomics analysis methods with endogenous reference metabolites | 2010 | BibTeX | RIS |
| Matthias Keller, Hans-Peter Deigner, David P. Enot, Matthias Kohl, Ronnaug Solberg, Ola D. Saugstad, Therese Koal | Method of Diagnosing Asphyxia | 2010 | BibTeX | RIS |
| Matthias Kohl, Hans-Peter Deigner | Preprocessing of gene expression data by optimally robust estimators | BMC Bioinformatics, 11.2010(1), 2010 | BibTeX | RIS DOIURN |
| William J. Griffiths, Therese Koal, Yuqin Wang, Matthias Kohl, David P. Enot, Hans-Peter Deigner | Targeted Metabolomics for Biomarker Discovery | Angewandte Chemie: International Edition, 49.2010(32), pp. 5426-5445, 2010 | BibTeX | RIS DOI |
| Hans-Peter Deigner, David P. Enot, Matthias Kohl, Ignatius E. Igwe, Therese Koal, Michael Bauer, Guido Dallmann | Use of Endogenous Metabolites for Early Diagnosing Sepsis | 2010 | BibTeX | RIS |
2009 | |||
| Johannes Winning, Julia Reichel, Yvonne Eisenhut, Jürg Hamacher, Matthias Kohl, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Wolfgang Lösche | Anti-platelet drugs and outcome in severe infection: Clinical impact and underlying mechanisms | Platelets, 20.2009(1), pp. 50-57, 2009 | BibTeX | RIS DOI |
| Ralf A. Claus, Michael J. Dorer, Alexander C. Bunck, Hans-Peter Deigner | Inhibition of Sphingomyelin Hydrolysis: Targeting the Lipid Mediator Ceramide as a Key Regulator of Cellular Fate | Current Medicinal Chemistry, 16.2009(16), pp. 1978-2000, 2009 | BibTeX | RIS |
| Salvatore Cuzzocrea, Hans-Peter Deigner, Tiziana Genovese, Emanuela Mazzon, Emanuela Esposito, Concetta Crisafulli, Rosanna Di Paola, Placido Bramanti, George Matuschak, Daniela Salvemini | Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury | Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, 31.2009(6), pp. 634-644, 2009 | BibTeX | RIS |
| Hans-Peter Deigner, Matthias Kohl | The molecular sepsis signature | Critical Care Medicine, 37.2009(3), pp. 1137-1138, 2009 | BibTeX | RIS DOI |
2008 | |||
| Ralf Kinscherf, Hans-Peter Deigner | Apoptogenic Signal Transduction in Arteriosclerosis-Associated Cells – Opportunities for Future Therapy? | Vascular Disease Prevention, 05.2008(2), pp. 116-128, 2008 | BibTeX | RIS |
| Hans-Peter Deigner, Albin Hermetter | Oxidized phospholipids: emerging lipid mediators in pathophysiology | Current Opinion in Lipidology, 19.2008(3), pp. 289-294, 2008 | BibTeX | RIS DOI |
2007 | |||
| Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Dan Turcanu, Helmut Heinle, Wulf Dröge, Jürgen Metz, Ralf Kinscherf | Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males | Journal of Molecular Medicine, 85.2007(2), pp. 181-190, 2007 | BibTeX | RIS DOI |
| Hans-Peter Deigner, E. Gulbins, Ralf A. Claus | Sphingolipid Metabolism in Systemic Inflammation | Intensive Care Medicine: 2007 Annual Update, Springer: Berlin, pp. 249-266, 2007 | BibTeX | RIS DOI 978-3-540-49433-1, |
2006 | |||
| Florian Setzer, Volker Oberle, Markus Bläss, Eva Möller, Stefan Rußwurm, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Konrad Reinhart, Wolfgang Lösche | Platelet-derived microvesicles induce differential gene expression in monocytic cells: A DNA microarray study | Platelets, 17.2006(8), pp. 571-576, 2006 | BibTeX | RIS DOI |
| M. Harz, Ralf A. Claus, Clemens L. Bockmeyer, M. Baum, P. Rösch, Karim Kentouche, Hans-Peter Deigner, Jürgen Popp | UV-Resonance Raman Spectroscopic Study of Human Plasma of Healthy Donors and Patients with Thrombotic Microangiopathy | Biopolymers, 82.2006(4), pp. 317-324, 2006 | BibTeX | RIS DOI |
2005 | |||
| Gabriel A. Bonaterra, Wulf Hildebrandt, Anne Bodens, Roland Sauer, Klaus A. Dugi, Hans-Peter Deigner, Wulf Dröge, Jürgen Metz, Ralf Kinscherf | Increased cyclooxygenase-2 expression in peripheral blood mononuclear cells of smokers and hyperlipidemic subjects | Free Radical Biology and Medicine, 38.2005(2), pp. 235-242, 2005 | BibTeX | RIS DOI |
| Ralf A. Claus, Alexander C. Bunck, Clemens L. Bockmeyer, Frank M. Brunkhorst, Wolfgang Lösche, Ralf Kinscherf, Hans-Peter Deigner | Role of increased sphingomyelinase activity in apoptosis and organ failure of patients with severe sepsis | The FASEB Journal, 19.2005(12), pp. 1719-1721, 2005 | BibTeX | RIS DOI |
| Ralf A. Claus, Annette Wüstholz, Stefan Müller, Clemens L. Bockmeyer, Norman H. Riedel, Ralf Kinscherf, Hans-Peter Deigner | Synthesis and Antiapoptotic Activity of a Novel Analogue of the Neutral Sphingomyelinase Inhibitor Scyphostatin | ChemBioChem, 6.2005(4), pp. 726-737, 2005 | BibTeX | RIS DOI |
| Thomas Hilberg, Hans-Peter Deigner, Eva Möller, Ralf A. Claus, Andriy Ruryk, Doreen Gläser, Julien Landre, Frank M. Brunkhorst, Konrad Reinhart, Holger H. Gabriel, Stefan Rußwurm | Transcription in response to physical stress - clues to the molecular mechanisms of exercise-induced asthma | The FASEB Journal, 19.2005(11), pp. 1492-1494, 2005 | BibTeX | RIS DOI |
| Ralf A. Claus, Clemens L. Bockmeyer, Karim Kentouche, Matthias W. Sieber, Volker Oberle, Roland Kaufmann, Hans-Peter Deigner, Wolfgang Lösche | Transcriptional regulation of ADAMTS13 | Thrombosis and Haemostasis, 94.2005(1), pp. 41-45, 2005 | BibTeX | RIS DOI |
| V. Tomic, Stefan Rußwurm, Eva Möller, Ralf A. Claus, Markus Bläss, Frank M. Brunkhorst, M. Brügel, K. Bode, F. Bloos, J. Wippermann, T. Wahlers, Hans-Peter Deigner, J. Thiery, Konrad Reinhart, Michael Bauer | Transcriptomic and Proteomic Patterns of Systemic Inflammation in On-Pump and Off-Pump Coronary Artery Bypass Grafting | Circulation, 112.2005(19), pp. 2912-2920, 2005 | BibTeX | RIS DOI |
2004 | |||
| Miroslav Prucha, Andriy Ruryk, Hinnerk Boriss, Eva Möller, Roman Zazula, Ivan Herold, Ralf A. Claus, Konrad Reinhart, Hans-Peter Deigner, Stefan Rußwurm | Expression profiling: toward an application in sepsis diagnostics | Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, 22.2004(1), pp. 29-33, 2004 | BibTeX | RIS DOI |
| Alexandra Loidl, Ralf A. Claus, Elisabeth Ingolic, Hans-Peter Deigner, Albin Hermetter | Role of ceramide in activation of stress-associated MAP kinases by minimally modified LDL in vascular smooth muscle cells | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1690.2004(2), pp. 150-158, 2004 | BibTeX | RIS DOI |
2003 | |||
| Ralf Kinscherf, Konstantinos Cafaltzis, Falk Röder, Wulf Hildebrandt, Lutz Edler, Hans-Peter Deigner, Raoul Breitkreutz, Giso Feussner, Jörg Kreuzer, Egon Werle, Gerd Michel, Jürgen Metz, Wulf Dröge | Cholesterol levels linked to abnormal plasma thiol concentrations and thiol/disulfide redox status in hyperlipidemic subjects | Free Radical Biology & Medicine, 35.2003(10), pp. 1286-1292, 2003 | BibTeX | RIS DOI |
| Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Jürgen Metz | Hypercholesterolemia-Induced Long-Term Increase of Macrophages in the Myocardium of New Zealand White Rabbits | Cells Tissues Organs, 174.2003(4), pp. 184-193, 2003 | BibTeX | RIS DOI |
| Stefan Rußwurm, Hans-Peter Deigner, Konrad Reinhart | Microarray technology in sepsis: tool or toy? | Yearbook of Intensive Care and Emergency Medicine 2003, pp. 55-64, Springer: Berlin, 2003 | BibTeX | RIS 3-540-44382-7, |
| Alexandra Loidl, Eva Sevcsik, Gernot Riesenhuber, Hans-Peter Deigner, Albin Hermetter | Oxidized Phospholipids in Minimally Modified Low Density Lipoprotein Induce Apoptotic Signaling via Activation of Acid Sphingomyelinase in Arterial Smooth Muscle Cells | Journal of Biological Chemistry, 278.2003(35), pp. 32921-32928, 2003 | BibTeX | RIS DOI |
2002 | |||
| Alexandra Loidl, Ralf A. Claus, Hans-Peter Deigner, Albin Hermetter | High-precision fluorescence assay for sphingomyelinase activity of isolated enzymes and cell lysates | The Journal of Lipid Research, 43.2002(5), pp. 815-823, 2002 | BibTeX | RIS |
2001 | |||
| Hans-Peter Deigner, Ralf A. Claus, Gabriel A. Bonaterra, Christof Gehrke, Nilofar Bibak, Markus Bläss, Michael Cantz, Jürgen Metz, Ralf Kinscherf | Ceramide induces aSMase expression: implications for oxLDL-induced apoptosis | The FASEB Journal, 15.2001(3), pp. 807-814, 2001 | BibTeX | RIS |
| Helmut Weicker, Ralf Kinscherf, Karin Diserens, Hans-Peter Deigner, Heiko Strüder | Physiology and pathophysiology of basalganglia: impact on motor system function | European Journal of Sport Science, 1.2001(2), pp. 1-46, 2001 | BibTeX | RIS |
| Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Matthias Wiederhold, Andrea Luber, Peter F. Zipfel, Hans-Peter Deigner, Konrad Reinhart | Procalcitonin and CGRP-I mRNA expression in various human tissues | Shock: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, 16.2001(2), pp. 109-112, 2001 | BibTeX | RIS DOI |
| Stefan Rußwurm, Ilmars Stonans, Elita Stonane, Peter F. Zipfel, Hans-Peter Deigner, Konrad Reinhart | Various human tissues express procalcitonin and CGRP-I mRNA | Journal für Anästhesie und Intensivbehandlung, pp. 55-58, 2001 | BibTeX | RIS |
2000 | |||
| Ralf A. Claus, Ralf Kinscherf, Christof Gehrke, Gabriel A. Bonaterra, Purusotam Basnet, Jürgen Metz, Hans-Peter Deigner | Antiapoptotic Effects of Propolis Extract and Propol on Human Macrophages Exposed to Minimally Modified Low Density Lipoprotein | Arzneimittel-Forschung = Drug research, 50.2000(4), pp. 373-379, 2000 | BibTeX | RIS |
| Hans-Peter Deigner, Uwe Haberkorn, Ralf Kinscherf | Apoptosis modulators in the therapy of neurodegenerative diseases | Expert Opinion on Investigational Drugs, 9.2000(4), pp. 747-764, 2000 | BibTeX | RIS DOI |
| Ralf A. Claus, Stefan Rußwurm, M. Meisner, Ralf Kinscherf, Hans-Peter Deigner | Modulation of the ceramide level, a novel therapeutic concept? | Current Drug Targets, 01.2000(2), pp. 185-205, 2000 | BibTeX | RIS |
1999 | |||
| Ralf Kinscherf, Martin Wagner, Huse Kamencic, Gabriel A. Bonaterra, Dongming Hou, Rainer A. Schiele, Hans-Peter Deigner, Jürgen Metz | Characterization of apoptotic macrophages in atheromatous tissue of humans and heritable hyperlipidemic rabbits | Atherosclerosis, 144.1999(1), pp. 33-39, 1999 | BibTeX | RIS DOI |
| Ilmars Stonans, Elita Stonane, Stefan Rußwurm, Hans-Peter Deigner, Konrad J. Böhm, Matthias Wiederhold, Lothar Jäger, Konrad Reinhart | HepG2 Human Hepatoma Cells Express Multiple Cytokine Genes | Cytokine, 11.1999(2), pp. 151-156, 1999 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Ralf Kinscherf | Modulating apoptosis: current applications and prospects for future drug development | Current Medicinal Chemistry, 06.1999(5), pp. 399-414, 1999 | BibTeX | RIS |
| Hans-Peter Deigner, Ralf Kinscherf, Ralf A. Claus, Beatrix Fyrnys, Christopher Blencowe, Albin Hermetter | Novel reversible, irreversible and fluorescent inhibitors of platelet-activating factor acetylhydrolase as mechanistic probes | Atherosclerosis, 144.1999(1), pp. 79-90, 1999 | BibTeX | RIS DOI |
1998 | |||
| Ralf Kinscherf, Ralf A. Claus, Martin Wagner, Christof Gehrke, Huse Kamencic, Dongming Hou, Olaf Nauen, Walther Schmiedt, Gyula Kovacs, Johannes Pill, Jürgen Metz, Hans-Peter Deigner | Apoptosis caused by oxidized LDL is manganese superoxide dismutase and p53 dependent | The FASEB Journal, 12.1998(6), pp. 461-467, 1998 | BibTeX | RIS DOI |
| Walther Schmiedt, Ralf Kinscherf, Hans-Peter Deigner, Huse Kamencic, Olaf Nauen, Juliane Kilo, Hellmut Oelert, Jürgen Metz, Sucharit Bhakdi | Complement C6 Deficiency Protects Against Diet-Induced Atherosclerosis in Rabbits | Arteriosclerosis, Thrombosis, and Vascular Biology, 18.1998(11), pp. 1790-1795, 1998 | BibTeX | RIS DOI |
1997 | |||
| Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Jürgen Metz | Der Einfluß von Veränderungen des Blut-Cholesterinspiegels auf Makrophagen im Myokard von Kaninchen | Adhäsionsmoleküle, Zytokine und Apoptose bei der Gefäßumgestaltung: 11. Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung 1997, pp. 230-234, 1997 | BibTeX | RIS 3-9804191-4-2, |
| Ralf Kinscherf, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, Walther Schmiedt, Michael Schrader, Jürgen Metz | Effect of alterations of blood cholesterol levels on macrophages in the myocardium of New Zealand White rabbits | Journal of Leukocyte Biology, 62.1997(6), pp. 719-725, 1997 | BibTeX | RIS DOI |
| Ralf Kinscherf, Hans-Peter Deigner, Claus Usinger, Johannes Pill, Martin Wagner, Huse Kamencic, Dongming Hou, Min Chen, Walther Schmiedt, Michael Schrader, Gyula Kovacs, Kanefusa Kato, Jürgen Metz | Induction of mitochondrial manganese superoxide dismutase in macrophages by oxidized LDL: its relevance in atherosclerosis of humans and heritable hyperlipidemic rabbits | The FASEB Journal, 11.1997(14), pp. 1317-1328, 1997 | BibTeX | RIS DOI |
| Ralf Kinscherf, Walther Schmiedt, Huse Kamencic, Hans-Peter Deigner, Johannes Pill, S. Bhakdi, Jürgen Metz | Komplement C6-Defizienz führt zu einem signifikant geringeren Anstieg von Makrophagen (CR3/43) und arteriosklerotischen Plaques in Cholesterin-gefütterten Kaninchen | Adhäsionsmoleküle, Zytokine und Apoptose bei der Gefäßumgestaltung: 11. Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung 1997, pp. 111-115, 1997 | BibTeX | RIS 3-9804191-4-2, |
| Ralf Kinscherf, Ralf A. Claus, Hans-Peter Deigner, Olaf Nauen, Christoph Gehrke, Albin Hermetter, Stefan Rußwurm, Volker Daniel, Volker Hack, Jürgen Metz | Modified low density lipoprotein delivers substrate for ceramide formation and stimulates the sphingomyelin-ceramide pathway in human macrophages | FEBS Letters, 405.1997(1), pp. 55-59, 1997 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Ralf A. Claus, Ralf Kinscherf | Modifiziertes LDL als Substratquelle für die Bildung von Ceramid | Adhäsionsmoleküle, Zytokine und Apoptose bei der Gefäßumgestaltung: 11. Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung 1997, pp. 45-50, 1997 | BibTeX | RIS 3-9804191-4-2, |
| Beatrix Fyrnys, Ralf A. Claus, Gert Wolf, Hans-Peter Deigner | Oxidized Low Density Lipoprotein Stimulates Protein Kinase C (PKC) Activity and Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Cells | Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 3, Springer US: Boston, pp. 93-98, 1997 | BibTeX | RIS 978-1-4899-1813-0, |
1996 | |||
| Ralf A. Claus, Beatrix Fyrnys, Hans-Peter Deigner, Gert Wolf | Oxidized Low-Density Lipoprotein Stimulates Protein Kinase C (PKC) and Induces Expression of PKC-Isotypes via Prostaglandin-H-Synthase in P388D1 Macrophage-Like Cells | Biochemistry, 35.1996(15), pp. 4911-4922, 1996 | BibTeX | RIS |
| M. A. Pajares, L. Alvarez, B. Gil Perez, M. L. Martinez Chantar, J. Mingorance, E. Sanchez Gongora, Hans-Peter Deigner, M. Avila, J. M. Mato | Regulation and structure of rat liver S-adenosylmethionine synthethase, a target enzyme for studies in liver injury | Methionine metabolism : molecular mechanism and clinical implications : proceedings of a workshop held at Sierra Nevada (Granada) on March 3-7-1996, pp. 2-10, 1996 | BibTeX | RIS |
| Hans-Peter Deigner, Ralf A. Claus | Stimulation of mitogen activated protein kinase by LDL and oxLDL in human U-937 macrophage-like cells | FEBS Letters, 385.1996(3), pp. 149-153, 1996 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Ralf A. Claus | ox LDL induzierte Tyrosinkinase-Aktivität | Endokrine und zellbiologische Aspekte der Arteriosklerose: 10. Jahrestagung der Deutschen Gesellschaft für Arterioskleroseforschung 1996, pp. 308-312, 1996 | BibTeX | RIS 3-9804191-2-6, |
1995 | |||
| Hans-Peter Deigner, Christian E. Freyberg, S. Laufer | Distribution and excretion of [14C]-labelled [2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5- yl]- [2'-14C]-acetic acid in rats | Arzneimittel-Forschung = Drug research, 45.1995(3), pp. 272-276, 1995 | BibTeX | RIS |
| Christopher Blencowe, Albin Hermetter, Gert M. Kostner, Hans-Peter Deigner | Enhanced Association of Platelet-activating Factor Acetylhydrolase with Lipoprotein (a) in Comparison with Low Density Lipoprotein | Journal of Biological Chemistry, 270.1995(52), pp. 31151-31157, 1995 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Christopher Blencowe, Christian E. Freyberg | Prevalence of steric restrictions in enzymatic nitrile-hydrolysis of a preparation from Rhodococcus sp. 409 | Journal of Molecular Catalysis B: Enzymatic, 01.1996(2), pp. 61-70, 1995 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Jose M. Mato, Maria A. Pajares | Study of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP | Biochemical Journal, 308.1995(2), pp. 565-571, 1995 | BibTeX | RIS |
| Beatrix Fyrnys, Christopher Blencowe, Hans-Peter Deigner | Susceptibility of phospholipids of oxidizing LDL to enzymatic hydrolysis modulates uptake by P388D1 macrophage-like cells | FEBS Letters, 357.1995(1), pp. 7-12, 1995 | BibTeX | RIS DOI |
1994 | |||
| Hans-Peter Deigner, G. Wolf, U. Ohlenmacher, J. Reichling | 1'-Hydroxyeugenol- and coniferyl alcohol derivatives as effective inhibitors of 5-lipoxygenase and Cu(2+)-mediated low density lipoprotein oxidation. Evidence for a dual mechanism | Arzneimittel-Forschung = Drug research, 44.1994(8), pp. 956-961, 1994 | BibTeX | RIS |
| Hans-Peter Deigner, G. Wolf | Oxidativ modifiziertes LDL und seine mögliche Rolle in der Atherogenese | Bioforum, Vol.17.1994, pp. 83-87, 1994 | BibTeX | RIS |
1993 | |||
| Hans-Peter Deigner, Christian E. Freyberg, R. Heck | Chemoenzymatic synthesis of carbon-14 labelled antioxidants | Journal of Labelled Compounds and Radiopharmaceuticals, 33.1993(3), pp. 171-180, 1993 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Hans A. Dresel | Effect of platelet activating factor on the kinetics of LDL oxidation in vitro | FEBS Letters, 317.1993(3), pp. 202-206, 1993 | BibTeX | RIS DOI |
| Hans-Peter Deigner, Beatrix Fyrnys | Synthesis of [32P]labelled 1-O-alkyl-2-desoxy-2-amino-sn′-glycero-3-phosphocholines | Journal of Labelled Compounds and Radiopharmaceuticals, 34.1994(2), pp. 185-189, 1993 | BibTeX | RIS DOI |
1992 | |||
| Hans-Peter Deigner, Beatrix Fyrnys | Rapid synthesis of 2-desoxy-2-amino-3-phosphocholine-glycerinic-acid-alkylester, 1-alkyl-1-desoxy- and 1-O-alkyl-2-desoxy-2-amino-sn-glycero-3-phosphocholines, -3-phospho-N,N′-dimethylethanolamine and -3-phospho-Fmoc-serine-methylester | Chemistry and Physics of Lipids, 61.1992(2), pp. 199-208, 1992 | BibTeX | RIS DOI |
| Hans-Peter Deigner, E. Friedrich, H. Sinn, Hans A. Dresel | Scavenging of lipid peroxidation products from oxidizing LDL by albumin alters the plasma half-life of a fraction of oxidized LDL particles | Free radical research communications, 16.1992(4), pp. 239-246, 1992 | BibTeX | RIS DOI |
1991 | |||
| Hans-Peter Deigner | Über eine mögliche Rolle von Proteinen bei der LDL-Oxidation | Pharmazeutische Zeitung, 136.1991(5/6), p. 269, 1991 | BibTeX | RIS |
1990 | |||
| Richard Neidlein, Take Constantinescu, Claus Krieger, Hans-Peter Deigner | A Convenient Solid-Support Procedure for the Synthesis of Symmetric Disulphides. The Configuration of Aromatic Carben Atoms in the 1,6-Methano[10]annulene Framework | Zeitschrift für Naturforschung B, 45.1990(11), pp. 1582-1588, 1990 | BibTeX | RIS DOI |
| Hans A. Dresel, Hans-Peter Deigner, J. Frübis, K. Strein, G. Schettler | LDL-metabolism of the arterial wall-new implications for atherogenesis | Zeitschrift für Kardiologie, 79.1990(Suppl. 3), pp. 9-16, 1990 | BibTeX | RIS |
1989 | |||
| Hans-Peter Deigner, Wing C. Law, Francisco J. Canada, Robert R. Rando | Membranes as the energy source in the endergonic transformation of vitamin A to 11-cis-retinols | Science, 244.1989(4907), pp. 968-971, 1989 | BibTeX | RIS DOI |
1988 | |||
| Richard Neidlein, Hans-Peter Deigner | Biotransformation of 4-Oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[5.2.1.0 2,6endo]dec-8-en-3on an der Ratte | Arzneimittel-Forschung = Drug research, 38.1988(2), pp. 260-266, 1988 | BibTeX | RIS |
| Richard Neidlein, Hans-Peter Deigner, W. Kramer | In vivo- und in vitro-Untersuchung von synthetischem Vergleichsmaterial zu Stoffwechselprodukten von 4-0xa-5-exo-(N-methylcarbamoyloxy-tricyclo[5.2.1.0.2,6endo]dec-8-en-3d-oenr Ratte | Archiv der Pharmazie, 321.1988(3), pp. 125-130, 1988 | BibTeX | RIS DOI |
| Richard Neidlein, Hans-Peter Deigner | Pharmakokinetik von 4-oxa-5-exo-(N-methylcarbamoyloxy)-tricyclo-[5:2.1.0. 2,6-endo]dec-8-en-3on an der Ratte | Arzneimittel-Forschung = Drug research, 38.1988(3), pp. 359-363, 1988 | BibTeX | RIS |