Prof. Dr. rer. nat. Matthias Kohl
Fakultät Medical and Life Sciences
Studiendekan Medical Diagnostic Technologies (MDT)
Telefon: 07720 307-4635
Fax: 07720 307-4725
Campus Villingen-Schwenningen, Raum B 2.07

Lehrgebiete:

  • Bioinformatik, Biostatistik
  • Data Mining, Statistiksoftware
  • Biomarker Entwicklung und Validierung
  • Molekulare Diagnostik

 

Aktuelle Projekte:

Publikationen

Matthias Kohl

2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004

2017

Ha-Yeun Chung, Anna S. Kollmey, Andrea Schrepper, Matthias Kohl, Markus Bläss, Sebastian N. Stehr, Amelie Lupp, Markus H. Gräler, Ralf A. Claus Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction
Wolfgang Kemmler, Anja Weissenfels, Michael Bebenek, Michael Fröhlich, Heinz Kleinöder, Matthias Kohl, Simon von Stengel Effects of Whole-Body Electromyostimulation on Low Back Pain in People with Chronic Unspecific Dorsal Pain: A Meta-Analysis of Individual Patient Data from Randomized Controlled WB-EMS Trials
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl Exercise Frequency and Fracture Risk in Older Adults—How Often Is Enough?
Wolfgang Kemmler, Matthias Kohl, Simon von Stengel Long-term effects of exercise in postmenopausal women: 16-year results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)
Markus Bläss, Nelly Bibak, Ralf A. Claus, Matthias Kohl, Gabriel A. Bonaterra, Ralf Kinscherf, Stefan Laufer, Hans-Peter Deigner NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation
Matthias Kohl Package mpe: Multiple Primary Endpoints
Andreas Wittke, Simon von Stengel, Michael Hettchen, Michael Fröhlich, Jürgen Giessing, Michael Lell, Michael Scharf, Michael Bebenek, Matthias Kohl, Wolfgang Kemmler Protein Supplementation to Augment the Effects of High Intensity Resistance Training in Untrained Middle-Aged Males: The Randomized Controlled PUSH Trial
Christoph König, Stephanie Tauchnitz, Heike Kunzelmann, Christian Horn, Frithjof Blessing, Matthias Kohl, Markus Egert Quantification and identification of aerobic bacteria in holy water samples from a German environment
Wolfgang Kemmler, Anja Weissenfels, Marc Teschler, Sebastian Willert, Michael Bebenek, Mahdieh Shojaa, Matthias Kohl, Ellen Freiberger, Cornel Sieber, Simon von Stengel Whole-body electromyostimulation and protein supplementation favorably affect sarcopenic obesity in community-dwelling older men at risk: the randomized controlled FranSO study

2016

Marc Teschler, Anja Weissenfels, Michael Froehlich, Matthias Kohl, Michael Bebenek, Simon von Stengel, Wolfgang Kemmler (Very) high creatine kinase (CK) levels after Whole-Body Electromyostimulation. Are there implications for health?
Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Andreas Kortgen, Eva Möller, Karen Felsmann, Jean Marc Cavaillon, Orlando Guntinas-Lichius, Olivier Rutschmann, Andriy Ruryk, Matthias Kohl, Britta Wlotzka, Stefan Rußwurm, John C. Marshall, Konrad Reinhart A Transcriptomic Biomarker to Quantify Systemic Inflammation in Sepsis — A Prospective Multicenter Phase II Diagnostic Study
Anne Jenner, Christian Lappe, Achim Zehender, Christian Horn, Frithjof Blessing, Matthias Kohl, Markus Egert A view to a kill? – ambient bacterial load of frames and lenses of spectacles and evaluation of different cleaning methods
Basri Gülbakan, Riza Köksal Özgül, Ayse Yüzbasioglu, Matthias Kohl, Hans-Peter Deigner, Meral Özgüc Discovery of biomarkers in rare diseases: innovative approaches by predictive and personalized medicine
Wolfgang Kemmler, Matthias Kohl, Simon von Stengel Effects Of High Intensity Resistance Training Versus Whole-Body Electromyostimulation On Cardio-Metabolic Risk Factors In Untrained Middle Aged Males. A Randomized Controlled Trail
Wolfgang Kemmler, Marc Teschler, Anja Weissenfels, Michael Bebenek, Michael Froehlich, Matthias Kohl, Simon von Stengel Effects of Whole-Body Electromyostimulation versus High-Intensity Resistance Exercise on Body Composition and Strength: A Randomized Controlled Study
Matthias Kohl Einführung in das Programmieren mit R
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl Exercise frequency and bone mineral density development in exercising postmenopausal osteopenic women. Is there a critical dose of exercise for affecting bone? Results of the Erlangen Fitness and Osteoporosis Prevention Study
Wolfgang Kemmler, Simon von Stengel, Matthias Kohl, Julia Bauer Impact of exercise changes on body composition during the college years - a five year randomized controlled study
Katharina Wittmann, Cornel Sieber, Simon von Stengel, Matthias Kohl, Ellen Freiberger, Franz Jakob, Michael Lell, Klaus Engelke, Wolfgang Kemmler Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: the randomized controlled FORMOsA sarcopenic obesity study
Christoph Sponholz, Katja Matthes, Dina Rupp, Wolf Backaus, Sebastian Klammt, Diana Karailieva, Astrid Bauschke, Utz Settmacher, Matthias Kohl, Mark G. Clemens, Steffen Mitzner, Michael Bauer, Andreas Kortgen Molecular adsorbent recirculating system and single pass albumin dialysis in liver failure -- a prospective randomized cross-over study
Wolfgang Kemmler, Simon von Stengel, Marc Teschler, Anja Weissenfels, Michael Bebenek, Matthias Kohl, Ellen Freiberger, C. Bollheimer, S. Goisser, Cornel Sieber, L. Seefried, Franz Jakob, Klaus Engelke Whole-body Electromyostimulation and Sarcopenic Obesity: Results of the randomized controlled FORMOsA-Sarcopenic Obesity Study
Wolfgang Kemmler, Marc Teschler, Anja Weissenfels, Michael Bebenek, Simon von Stengel, Matthias Kohl, Ellen Freiberger, S. Goisser, Franz Jakob, Cornel Sieber, Klaus Engelke Whole-body electromyostimulation to fight sarcopenic obesity in community-dwelling older women at risk. Results of the randomized controlled FORMOsA-sarcopenic obesity study

2015

Markus Egert, Kerstin Späth, Karoline Weik, Heike Kunzelmann, Christian Horn, Matthias Kohl, Frithjof Blessing Bacteria on smartphone touchscreens in a German university setting and evaluation of two popular cleaning methods using commercially available cleaning products
Matthias Kohl Einführung in die statistische Datenanalyse mit R
Wolfgang Kemmler, Matthias Kohl, Michael Bebenek, Simon von Stengel Entwicklung von Übergewicht und Adipositas im jungen Erwachsenenalter – Stellenwert berufsbedingter Veränderungen des Sporttreibens auf Fettmasse, fettfreie Masse und Körpermasse bei Studenten
Wolfgang Kemmler, Michael Bebenek, Matthias Kohl, Simon von Stengel Exercise and fractures in postmenopausal women. Final results of the controlled Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)
Wolfgang Kemmler, Marc Teschler, Anja Weissenfels, Michael Froehlich, Matthias Kohl, Simon von Stengel Ganzkörper Elektromyostimulation versus HIT-Krafttraining – Einfluss auf Körperzusammensetzung und Muskelkraft
Wolfgang Kemmler, Michael Bebenek, Simon von Stengel, Matthias Kohl, Julia Bauer Increases of Cardiometabolic Risk in Young Adults. Impact of Exercise Reductions during the College Years
Matthias Kohl Introduction to statistical data analysis with R
Wolfgang Kemmler, Matthias Kohl, Michael Bebenek, Simon von Stengel Körperliche Belastung und kardiometabolisches Risiko bei jungen Erwachsenen
Wolfgang Kemmler, Michael Bebenek, Matthias Kohl, Simon von Stengel Körperliches Training, Fraktur und Knochendichte: Finale Ergebnisse der Erlanger Fitness und Osteoporose-Präventions-Studie (EFOPS)
Daria Pupashenko, Peter Ruckdeschel, Matthias Kohl L2 Differentiability of Generalized Linear Models
Christoph Ruppert, Matthias Kohl, Lisa Jacob, Hans-Peter Deigner Multiplexing in Bioassays
Gordon P. Otto, Jorge Hurtado-Oliverso, Ha-Yeun Chung, Kristin Knoll, Thomas Neumann, Hans J. Müller, Marco Herbsleb, Matthias Kohl, Maik Sossdorf, Ralf A. Claus, Martin Busch Plasma neutrophil gelatinase-associated lipocalin is primarily related to inflammation during sepsis: A translational approach
Markus Bläss, H.P. Le, Ralf A. Claus, Matthias Kohl, Hans-Peter Deigner Stereospecific Induction of Apoptosis in Tumor Cells via Endogenous C16-Ceramide and Distinct Transcripts

2014

James R. Perkins, Ana Antunes-Martins, Margarita Calvo, John Grist, Werner Rust, Ramona Schmid, Tobias Hildebrandt, Matthias Kohl, Christine Orengo, Stephen B. McMahon, David L. Bennett A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat
Matthias W. Sieber, Madlen Guenther, Nadine Jaenisch, Daniela Albrecht-Eckardt, Matthias Kohl, Otto W. Witte, Christiane Frahm Age-specific transcriptional response to stroke
Peter Ruckdeschel, Matthias Kohl General Purpose Convolution Algorithm in S4-Classes by Means of FFT
Kerstin Späth, Karoline Weik, Heike Kunzelmann, Christian Horn, Matthias Kohl, Frithjof Blessing, Markus Egert You will never talk alone: Bacteria on smartphone touchscreens in a German university setting and evaluation of two popular cleaning methods

2013

Matthias Kohl Analyse von Genexpressionsdaten mit R und Bioconductor
Fabienne Flessa, Alexandra Kehl, Matthias Kohl Analysing diversity and community structures using PCR-RFLP: a new software application
T. Peters, A. Ghadiri, Matthias Kohl Betriebliches Gesundheitsmanagement: audiovisuelle Entspannung kann Krankenstand senken
Ole Bayer, Daniel Schwarzkopf, Torsten Doenst, Deborah Cook, Björn Kabisch, Christoph Schelenz, Michael Bauer, Niels C. Riedemann, Yasser Sakr, Matthias Kohl, Konrad Reinhart, Christiane S. Hartog Perioperative Fluid Therapy With Tetrastarch and Gelatin in Cardiac Surgery — A Prospective Sequential Analysis
Maik Sossdorf, Gordon P. Otto, Katja Menge, Ralf A. Claus, Wolfgang Lösche, Björn Kabisch, Matthias Kohl, Ulrich C. Smolenski, Peter Schlattmann, Konrad Reinhart, Johannes Winning Potential effect of physiotherapeutic treatment on mortality rate in patients with severe sepsis and septic shock: A retrospective cohort analysis
Klaus Pöttgen, Matthias Kohl Propriozeption im Fußball

2012

Matthias Kohl Analysis of Microarray Data
James R. Perkins, Nor Izayu Abdul Rahman, Matthias Kohl Analysis of RT-qPCR data
Matthias Kohl Bounded influence estimation for regression and scale
Ole Bayer, Konrad Reinhart, Matthias Kohl, Björn Kabisch, John Marshall, Yasser Sakr, Michael Bauer, Christiane Hartog, Daniel Schwarzkopf, Niels Riedemann Effects of fluid resuscitation with synthetic colloids or crystalloids alone on shock reversal, fluid balance, and patient outcomes in patients with severe sepsis: A prospective sequential analysis
Matthias Kohl Feature Selection in Statistical Classification
Martina Weber, Sandro Lambeck, Nadine Ding, Stefanie Henken, Matthias Kohl, Hans-Peter Deigner, David P. Enot, Ignatius E. Igwe, Lucien Frappart, Michael Kiehntopf, Ralf A. Claus, Thomas Kamradt, Debra Weih, Yoram Vodovotz, David E. Briles, Abiodun D. Ogunniyi, James C. Paton, Ulrich A. Maus, Michael Bauer Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia
Yasser Sakr, Juliana Marques, Stefan Mortsch, Matheus D. Gonsalves, Khosro Hekmat, Björn Kabisch, Matthias Kohl, Konrad Reinhart Is the SAPS II score Valid in Surgical Intensive Care Unit Patients?
Matthias Kohl Performance Measures in Binary Classification
Uwe Kern, Volker Busch, Ruben Müller, Matthias Kohl, Frank Birklein Phantom Limb Pain in Daily Practice—Still a Lot of Work to Do!
James R. Perkins, John M. Dawes, Steve B. McMahon, David L. Bennett, Christine Orengo, Matthias Kohl ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
K.-U. Kern, Matthias Kohl, U. Seifert, T. Schlereth Wirkung von Botulinumtoxin Typ B auf Stumpfschwitzen und Stumpfschmerzen

2011

Christiane S. Hartog, Matthias Kohl, Konrad Reinhart A Systematic Review of Third-Generation Hydroxyethyl Starch (HES 130/0.4) in Resuscitation: Safety Not Adequately Addressed
James Perkins, Matthias Kohl Bioconductor-Package NormqPCR: Functions for normalisation of RT-qPCR data
James Perkins, Matthias Kohl, Nor Izayu Abdul Rahman Bioconductor-Package ReadqPCR: Read qPCR data
Uwe Kern, Matthias Kohl, Ulrich Seifert, Tanja Schlereth Botulinum toxin type B in the treatment of residual limb hyperhidrosis for lower limb amputees: a pilot study.
Matthias Kohl, S. Koch, M. Keller, Hans-Peter Deigner Bright Future in Clinical Dx?
Suzanne Perz, Thomas Uhlig, Matthias Kohl, Donald L. Bredle, Konrad Reinhart, Michael Bauer, Andreas Kortgen Low and “supranormal” central venous oxygen saturation and markers of tissue hypoxia in cardiac surgery patients – a prospective observational study.
Hans-Peter Deigner, Michael Bauer, Matthias Kohl Method for in vitro diagnosing sepsis utilizing biomarker composed of more than two different types of endogenous biomolecules
Ole Bayer, Konrad Reinhart, Yasser Sakr, Björn Kabisch, Matthias Kohl, Niels C. Riedemann, Michael Bauer, Utz Settmacher, Khosro Hekmat, Christiane S. Hartog Renal effects of synthetic colloids and crystalloids in patients with severe sepsis – a prospective sequential comparison
Hans-Peter Deigner, Matthias Kohl, Therese Koal, Ignatius E. Igwe, Guido Dallmann, Michael Bauer, David Enot Use of bile acids for prediction of an onset of sepsis

2010

Julien B. Landré, Markus Bläss, Matthias Kohl, Tina Schlicksbier, Andriy Ruryk, Ralf Kinscherf, Ralf A. Claus, Albin Hermetter, Matthias Keller, Michael Bauer, Hans-Peter Deigner Addressable bipartite molecular hook (ABMH): Immobilized hairpin probes with sensitivity below 50 fM
Johannes Winning, Jens Neumann, Matthias Kohl, Ralf A. Claus, Konrad Reinhart, Michael Bauer, Wolfgang Lösche Antiplatelet drugs and outcome in mixed admissions to an intensive care unit
Matthias Kohl Development and Validation of Predictive Molecular Signatures
Matthias Kohl, Peter Ruckdeschel, Helmut Rieder Infinitesimally Robust estimation in general smoothly parametrized models
M.W. Sieber, M. Günther, Matthias Kohl, O.W. Witte, R.A. Claus, C. Frahm Inter-age variability of bona fide unvaried transcripts: Normalization of quantitative PCR data in ischemic stroke
Uwe Kern, Matthias Kohl, Ralph T. Kiefer Lidocain-Pflaster zur Therapie neuropathischer und nichtneuropathischer Schmerzen
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal, Klaus Weinberger Method for In Vitro Diagnosing a Complex Disease
Hans-Peter Deigner, Matthias Kohl, David Enot, Therese Koal, Matthias Keller Method for Predicting the Likelihood of an Onset of an Inflammation Associated Organ Failure
Hans-Peter Deigner, Matthias Kohl, Matthias Keller, Therese Koal Method for normalization in metabolomics analysis methods with endogenous reference metabolites
Matthias Keller, Hans-Peter Deigner, David Enot, Matthias Kohl, Ronnaug Solberg, Didirik O. Saugstad, Therese Koal Method of Diagnosing Asphyxia
Fabienne Flessa, Alexandra Kehl, Mohamed A. Imtiaz, Matthias Kohl Package RFLPtools: Tools to analyse RFLP data
Matthias Kohl, Hans-Peter Deigner Preprocessing of gene expression data by optimally robust estimators.
Matthias Kohl, Peter Ruckdeschel R Package distrMod:S4 Classes and Methods for Probability Models
William J. Griffiths, Therese Koal, Yuqin Wang, Matthias Kohl, David P. Enot, Hans-Peter Deigner Targeted Metabolomics for Biomarker Discovery
Leming Shi, Gregory Campbell, Wendell D. Jones, Fabien Campagne, Zhining Wen, Stephen J. Walker, Zhenqiang Su, Tzu-Ming Chu, Federico M. Goodsaid, Lajos Pusztai, Matthias Kohl The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
Hans-Peter Deigner, David Enot, Matthias Kohl, Ignatius E. Igwe, Therese Koal, Michael Bauer, Guido Dallmann Use of Endogenous Metabolites for Early Diagnosing Sepsis
David Gräßel, Thomas M. Ringer, Clemens Fitzek, Sabine Fitzek, Matthias Kohl, Werner A. Kaiser, Otto W. Witte, Hubertus Axer Wallerian Degeneration of Pyramidal Tract After Paramedian Pons Infarct

2009

Johannes Winning, Julia Reichel, Yvonne Eisenhut, Jürg Hamacher, Matthias Kohl, Hans-Peter Deigner, Ralf A. Claus, Michael Bauer, Wolfgang Lösche Anti-platelet drugs and outcome in severe infection: Clinical impact and underlying mechanisms
Matthias Kohl Package ROptEstOld: Optimally robust estimation - old version
Matthias Kohl Package RobLoxBioC: Infinitesimally robust estimators for preprocessing omics data
Uwe Kern, Volker Busch, M. Rockland, Matthias Kohl, Frank Birklein Prävalenz und Risikofaktoren von Phantomschmerzen und Phantomwahrnehmungen in Deutschland
Hans-Peter Deigner, Matthias Kohl The molecular sepsis signature

2008

Matthias Kohl Package MKmisc: Miscellaneous Functions from M. Kohl
Matthias Kohl, Peter Ruckdeschel, Myhailo Pupashenko, Gerald Kroisandt Package RobAStBase: Robust Asymptotic Statistics
Matthias Kohl, Peter Ruckdeschel Package distrMod: Object orientated implementation of probability models.
Helmut Rieder, Matthias Kohl, Peter Ruckdeschel The cost of not knowing the radius
Eleonora Feist, Matthias Kohl, Peter Ruckdeschel, Anja Hueller distrTeach: Extensions of Package distr for Teaching Stochastics/Statistics in Secondary School

2007

Matthias Kohl Bioconductor-Package SLqPCR: Functions for analysis of real-time quantitative PCR data at SIRS-Lab GmbH
Matthias Kohl Package ROptEst: Optimally robust estimation
Matthias Kohl, Peter Ruckdeschel Package ROptRegTS: Optimally robust estimation for regressiontype models
Matthias Kohl Package RobRex: Optimally robust influence curves for regression and scale
Matthias Kohl Package SLmisc: Miscellaneous Functions for analysis of gene expression data at SIRS-Lab GmbH

2006

Uwe Kern, Bernd Altkemper, Matthias Kohl Management of Phantom Pain with a Textile, Electromagnetically-Acting Stump Liner: A Randomized, Double-Blind, Crossover Study
Peter Ruckdeschel, Matthias Kohl, Thomas Stabla, Florian Camphausen S4Classes for Distributions
Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla distrDoc: Documentation for packages distr, distrEx, distrSim, distrTEst, distrTeach, distrMod and distrEllipse

2005

Matthias Kohl Numerical Contributions to the Asymptotic Theory of Robustness
Matthias Kohl, Peter Ruckdeschel Package RandVar: Implementation of random variables by means of S4 classes and methods
Matthias Kohl, Peter Ruckdeschel Package distrEx: Extensions of package distr
Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla Package distrSim: Simulation classes based on package distr
Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla Package distrTEst: Estimation and testing classes based on package distr.

2004

Florian Camphausen, Matthias Kohl, Peter Ruckdeschel, Thomas Stabla Package distr: Object orientated implementation of distributions